Jianhua Li

Overview

Best Publications

• Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation.

  Hong Wang;Man Yu;Mahendar Ochani;Carol Ann Amella

  4010
  Citations

• Reversing established sepsis with antagonists of endogenous high-mobility group box 1

  Huan Yang;Mahendar Ochani;Jianhua Li;Xiaoling Qiang

  1448
  Citations

• The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

  Allan Tsung;Rohit Sahai;Hiroyuki Tanaka;Atsunori Nakao

  1442
  Citations

• A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

  Huan Yang;Hulda S. Hreggvidsdottir;Karin Palmblad;Haichao Wang

  947
  Citations

• Novel role of PKR in inflammasome activation and HMGB1 release

  Ben Lu;Takahisa Nakamura;Karen Inouye;Jianhua Li

  861
  Citations

• High Mobility Group Box Protein 1: An Endogenous Signal for Dendritic Cell Maturation and Th1 Polarization

  Davorka Messmer;Huan Yang;Huan Yang;Gloria Telusma;Faye Knoll

  603
  Citations

• The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis

  Meihong Deng;Yiting Tang;Wenbo Li;Xiangyu Wang

  566
  Citations

• Structural basis for the proinflammatory cytokine activity of high mobility group box 1.

  Jianhua Li;Riikka Kokkola;Siamak Tabibzadeh;Runkuan Yang

  546
  Citations

• IFN-γ Induces High Mobility Group Box 1 Protein Release Partly Through a TNF-Dependent Mechanism

  Beatriz Rendon-Mitchell;Mahendar Ochani;Jianhua Li;Jialian Han

  416
  Citations

• JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

  Ben Lu;Daniel J. Antoine;Kevin Kwan;Peter Lundbäck

  403
  Citations

• MD-2 is required for disulfide HMGB1-dependent TLR4 signaling

  Huan Yang;Haichao Wang;Zhongliang Ju;Ahmed A. Ragab

  389
  Citations

• Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms.

  Guoqian Chen;Jianhua Li;Mahendar Ochani;Beatriz Rendon-Mitchell

  263
  Citations

• HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells

  Katherine H. Parker;Pratima Sinha;Lucas A. Horn;Virginia K. Clements

  228
  Citations

• α7 Nicotinic Acetylcholine Receptor Signaling Inhibits Inflammasome Activation by Preventing Mitochondrial DNA Release

  Ben Lu;Kevin Kwan;Yaakov A. Levine;Peder S. Olofsson

  215
  Citations

• EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages.

  Wei Li;Shu Zhu;Shu Zhu;Jianhua Li;Andrei Assa

  211
  Citations

• Recombinant HMGB1 with cytokine-stimulating activity.

  Jianhua Li;Haichao Wang;James M Mason;Jacob Levine

  200
  Citations

• A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1

  Wei Li;Mala Ashok;Jianhua Li;Huan Yang

  191
  Citations

• A Cardiovascular Drug Rescues Mice from Lethal Sepsis by Selectively Attenuating a Late-Acting Proinflammatory Mediator, High Mobility Group Box 1

  Wei Li;Jianhua Li;Mala Ashok;Rongqian Wu

  184
  Citations

• A Hepatic Protein, Fetuin-A, Occupies a Protective Role in Lethal Systemic Inflammation

  Wei Li;Wei Li;Shu Zhu;Shu Zhu;Jianhua Li;Yan Huang;Yan Huang

  168
  Citations

• Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury.

  Kunihiko Izuishi;Allan Tsung;Geetha Jeyabalan;Nathan D. Critchlow

  167
  Citations