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Medicine

D-Index
147
Citations
74765
World Ranking
1299
National Ranking
136

Overview

Anthony Howell is affiliated with the University of Manchester in the United Kingdom. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. The scientist's work is concentrated in several subfields including Genetics, Oncology, Cancer Research, Public Health, Environmental and Occupational Health, and Molecular Biology.

The scientist's research covers a range of topics primarily focused on breast cancer and genetic risk factors. Main topics of study include:

  • BRCA gene mutations in cancer
  • Cancer Risks and Factors
  • Global Cancer Incidence and Screening
  • Genetic Associations and Epidemiology
  • Breast Cancer Treatment Studies
  • Cancer Genomics and Diagnostics
  • Nutritional Studies and Diet

Anthony Howell has contributed to several recent publications, highlighting ongoing work in cancer genetics and epidemiology. Some of their recent papers include:

  • Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women, 2021, New England Journal of Medicine
  • What are the benefits and harms of risk stratified screening as part of the NHS breast screening Programme? Study protocol for a multi-site non-randomised comparison of BC-predict versus usual screening (NCT04359420), 2020, BMC Cancer
  • Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study, 2022, British Journal of Sports Medicine
  • Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk, 2020, JNCI Journal of the National Cancer Institute
  • Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk, 2020, The American Journal of Human Genetics

The scientist frequently collaborates with other researchers in the field. Key co-authors include:

  • D. Gareth Evans
  • Sacha J. Howell
  • Elaine F. Harkness
  • Manjeet K. Bolla
  • William G. Newman

Publications by Anthony Howell appear often in well-known venues related to oncology and genetics. Frequent venues for publication include:

  • British Journal of Cancer
  • Cancers
  • Journal of Medical Genetics
  • Research Square (Research Square)
  • Genetics in Medicine

Best Publications

  • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

    O. Abe;R. Abe;K. Enomoto;K. Kikuchi

  • Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Early Breast Cancer Trialists' Collaborative Group.

    Anthony Howell;G Ribeiro;Ric Swindell

  • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer

    Anthony Howell

  • Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial.

    Jack Cuzick;Ivana Sestak;Michael Baum;Aman U Buzdar

  • Adjuvant docetaxel for node-positive breast cancer.

    Miguel Martin;Tadeusz Pienkowski;John R Mackey;Marek Pawlicki

  • Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: a phase III, double-blind, comparative trial.

    Lee S. Rosen;David Gordon;Mary Kaminski;Anthony Howell

  • Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses

    M Baum;A Buzdar;J Cuzick;J Forbes

  • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial.

    Lee S Rosen;David Gordon;Mary Kaminski;Anthony Howell

  • The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

    Michelle N. Harvie;Mary Pegington;Mark P. Mattson;Jan Frystyk

  • Prognostic Value of a Combined Estrogen Receptor, Progesterone Receptor, Ki-67, and Human Epidermal Growth Factor Receptor 2 Immunohistochemical Score and Comparison With the Genomic Health Recurrence Score in Early Breast Cancer

    Jack Cuzick;Mitch Dowsett;Silvia Pineda;Christopher Wale

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Prediction of Risk of Distant Recurrence Using the 21-Gene Recurrence Score in Node-Negative and Node-Positive Postmenopausal Patients With Breast Cancer Treated With Anastrozole or Tamoxifen: A TransATAC Study

    Mitch Dowsett;Jack Cuzick;Christopher Wale;John Forbes

  • First results from the International Breast Cancer Intervention Study (IBIS-I): a randomised prevention trial.

    J Cuzick;J Forbes;R Edwards;M Baum

  • Fulvestrant, Formerly ICI 182,780, Is as Effective as Anastrozole in Postmenopausal Women With Advanced Breast Cancer Progressing After Prior Endocrine Treatment

    Anthony Howell;John F R Robertson;J Quaresma Albano;A Aschermannova

  • Dissociation between Steroid Receptor Expression and Cell Proliferation in the Human Breast

    Robert B. Clarke;Anthony Howell;Christopher S. Potten;Elizabeth Anderson

  • Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women

    Leila Dorling;Sara Carvalho;Jamie Allen

  • Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

    Gloria Bonuccelli;Aristotelis Tsirigos;Diana Whitaker-Menezes;Stephanos Pavlides

  • Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases: A double-blind, randomized dose-response study

    James R. Berenson;Lee S. Rosen;Anthony Howell;Lester Porter

  • Effects of radiotherapy and surgery in early breast cancer. An overview of the randomized trials. Early Breast Cancer Trialists' Collaborative Group.

    Anthony Howell;G Ribeiro;Ric Swindell

  • Long-Term Results of Tamoxifen Prophylaxis for Breast Cancer—96-Month Follow-up of the Randomized IBIS-I Trial

    Jack Cuzick;John F. Forbes;Ivana Sestak;Simon Cawthorn

Frequent Co-Authors

D. Gareth Evans
D. Gareth Evans University of Manchester
Jack Cuzick
Jack Cuzick Queen Mary University of London
Michael P. Lisanti
Michael P. Lisanti University of Salford
Federica Sotgia
Federica Sotgia University of Salford
Fiona Lalloo
Fiona Lalloo University of Manchester
Robert Clarke
Robert Clarke University of Oxford
Ubaldo E. Martinez-Outschoorn
Ubaldo E. Martinez-Outschoorn Thomas Jefferson University
Richard G. Pestell
Richard G. Pestell The Wistar Institute
John F. Forbes
John F. Forbes University of Limerick
Diana Whitaker-Menezes
Diana Whitaker-Menezes Thomas Jefferson University

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