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Overview

Mitch Dowsett is affiliated with the Breast Cancer Research Foundation in the United States. Their research primarily spans the intersection of biochemistry, genetics, molecular biology, and medicine, with a significant focus on cancer research and oncology. Their work includes substantial contributions in subfields such as cancer research, genetics, pulmonary and respiratory medicine, and molecular biology.

Their publication record includes 111 works in both biochemistry, genetics and molecular biology, and medicine. Within these disciplines, Dowsett has concentrated on key themes related to breast cancer treatment and its underlying biological mechanisms.

Frequent topics in Dowsett's research include:

  • Breast Cancer Treatment Studies
  • Advanced Breast Cancer Therapies
  • Estrogen and related hormone effects
  • HER2/EGFR in Cancer Research
  • Cancer Genomics and Diagnostics
  • Breast Lesions and Carcinomas
  • Cancer Risks and Factors

Dowsett has collaborated extensively with other researchers, with noted frequent co-authors being:

  • Judith M. Bliss
  • Eugene F. Schuster
  • Jack Cuzick
  • J.F.R. Robertson
  • Maggie C.U. Cheang

Their work appears prominently in several publication venues, including:

  • Cancer Research (30 publications)
  • Journal of Clinical Oncology (9 publications)
  • Clinical Cancer Research (6 publications)
  • npj Breast Cancer (4 publications)
  • Breast Cancer Research (4 publications)

Selected recent papers authored or co-authored by Mitch Dowsett include:

  • Estrogen and Progesterone Receptor Testing in Breast Cancer: ASCO/CAP Guideline Update, 2020, Journal of Clinical Oncology
  • Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group, 2020, JNCI Journal of the National Cancer Institute
  • Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: ASCO-College of American Pathologists Guideline Update, 2023, Journal of Clinical Oncology
  • Estrogen and Progesterone Receptor Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Guideline Update, 2020, Archives of Pathology & Laboratory Medicine
  • Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13,864 women in seven randomised trials, 2021, The Lancet Oncology

Best Publications

  • American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer

    M. Elizabeth H. Hammond;Daniel F Hayes;Mitch Dowsett;D Craig Allred

  • Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

    Martine J. Piccart-Gebhart;Marion Procter;Brian Leyland-Jones;Aron Goldhirsch

  • American society of clinical oncology/college of american pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer

    Antonio C. Wolff;M. Elizabeth H. Hammond;Jared N. Schwartz;Karen L. Hagerty

  • Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer

    Antonio C Wolff;M Elizabeth Hale Hammond;Kimberly H Allison;Brittany E Harvey

  • Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update.

    Antonio C. Wolff;M. Elizabeth H Hammond;David G. Hicks;Mitch Dowsett

  • Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials

    C Davies;J Godwin;Richard Gray

  • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer

    Anthony Howell

  • Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group

    Mitch Dowsett;Torsten O. Nielsen;Roger A’Hern;John Bartlett

  • 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial

    Ian Smith;Marion Procter;Richard D Gelber;Sébastien Guillaume

  • Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

    Georgios Vlachogiannis;Somaieh Hedayat;Alexandra Vatsiou;Yann Jamin

  • Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial.

    Jack Cuzick;Ivana Sestak;Michael Baum;Aman U Buzdar

  • Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women.

    T J Key;P N Appleby;G K Reeves;A Roddam

  • 20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years.

    Hongchao Pan;Richard Gray;Jeremy Braybrooke;Christina Davies

  • Aromatase Inhibitors in Breast Cancer

    Ian E. Smith;Mitch Dowsett

  • Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial

    Trevor Powles;Ros Eeles;Sue Ashley;Doug Easton

  • Mutation Tracking in Circulating Tumor DNA Predicts Relapse in Early Breast Cancer

    Isaac Garcia-Murillas;Gaia Schiavon;Gaia Schiavon;Britta Weigelt;Charlotte Ng

  • Proliferation Marker Ki-67 in Early Breast Cancer

    Ander Urruticoechea;Ian E. Smith;Mitch Dowsett

  • Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials

    M Dowsett;JF Forbes;JF Forbes;Matti Hakama

  • Phase I Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone Acetate, Confirms That Castration-Resistant Prostate Cancer Commonly Remains Hormone Driven

    Gerhardt Attard;Alison H.M. Reid;Timothy A. Yap;Florence Raynaud

  • Neoadjuvant Treatment of Postmenopausal Breast Cancer With Anastrozole, Tamoxifen, or Both in Combination: The Immediate Preoperative Anastrozole, Tamoxifen, or Combined With Tamoxifen (IMPACT) Multicenter Double-Blind Randomized Trial

    Ian E. Smith;Mitch Dowsett;Stephen R. Ebbs;J. Michael Dixon

Frequent Co-Authors

Jack Cuzick
Jack Cuzick Queen Mary University of London
Judith M. Bliss
Judith M. Bliss Institute of Cancer Research
Nicholas C. Turner
Nicholas C. Turner Royal Marsden NHS Foundation Trust
Giuseppe Viale
Giuseppe Viale University of Milan
John F. Forbes
John F. Forbes University of Limerick
Roger A'Hern
Roger A'Hern Royal Marsden NHS Foundation Trust
Daniel F. Hayes
Daniel F. Hayes University of Michigan–Ann Arbor
Anthony Howell
Anthony Howell University of Manchester
Per Eystein Lønning
Per Eystein Lønning Haukeland University Hospital
Alan Ashworth
Alan Ashworth University of California, San Francisco

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