Alan Bernstein

Overview

Best Publications

• The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus.

  Benoit Chabot;Dennis A. Stephenson;Verne M. Chapman;Peter Besmer

  1766
  Citations

• W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity

  J D Huizinga;L Thuneberg;M Klüppel;M Klüppel;J Malysz

  1658
  Citations

• RNA tumor viruses

  Robin Weiss;A. Bernstein

  1337
  Citations

• A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis.

  Fouad Shalaby;Jacqueline Ho;William L. Stanford;Klaus Dieter Fischer

  1192
  Citations

• Grand challenges in chronic non-communicable diseases

  Abdallah S. Daar;Peter A. Singer;Deepa Leah Persad;Stig K. Pramming

  893
  Citations

• Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells.

  Seiji Hitoshi;Tania Alexson;Vincent Tropepe;Dorit Donoviel

  862
  Citations

• p53 Mutations increase resistance to ionizing radiation

  Jonathan M. Lee;Alan Bernstein

  819
  Citations

• Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice

  John E. Dick;Maria Cristina Magli;Dennis Huszar;Robert A. Phillips

  809
  Citations

• THE RECEPTOR TYROSINE KINASE TIE IS REQUIRED FOR INTEGRITY AND SURVIVAL OF VASCULAR ENDOTHELIAL-CELLS

  M C Puri;J Rossant;K Alitalo;A Bernstein

  642
  Citations

• Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice.

  K Nocka;S Majumder;B Chabot;P Ray

  595
  Citations

• Mice lacking both presenilin genes exhibit early embryonic patterning defects.

  Dorit B. Donoviel;Anna-Katerina Hadjantonakis;Masaki Ikeda;Hui Zheng

  594
  Citations

• Presenilins are required for γ -secretase cleavage of β -APP and transmembrane cleavage of Notch-1

  Zhuohua Zhang;Philip Nadeau;Weihong Song;Dorit Donoviel

  537
  Citations

• Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor.

  K.-D. Fischer;Y.-Y. Kong;H. Nishina;K. Tedford

  507
  Citations

• High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene.

  A Lavigueur;V Maltby;D Mock;J Rossant

  491
  Citations

• Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1.

  Y Ben-David;E B Giddens;K Letwin;A Bernstein

  487
  Citations

• Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus

  Michael Mowat;Michael Mowat;Ambrose Cheng;Ambrose Cheng;Nobuhiro Kimura;Nobuhiro Kimura;Alan Bernstein;Alan Bernstein

  451
  Citations

• Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

  Hiroshi Nishina;Klaus D. Fischer;Klaus D. Fischer;Laszlo Radvanyi;Arda Shahinian

  436
  Citations

• Fli-1 Is Required for Murine Vascular and Megakaryocytic Development and Is Hemizygously Deleted in Patients with Thrombocytopenia

  Adam Hart;Fabrice Melet;Paul Grossfeld;Kenneth Chien

  432
  Citations

• W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor

  A D Reith;R Rottapel;E Giddens;C Brady

  374
  Citations

• The c-kit receptor ligand functions as a mast cell chemoattractant.

  Cynthia J. Meininger;Hiroshi Yano;Robert Rottapel;Alan Bernstein

  365
  Citations