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Medicine

D-Index
93
Citations
26751
World Ranking
11006
National Ranking
5664

Overview

Sean M. Ward is affiliated with the University of Nevada Reno in the United States. Their research primarily spans the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Within these domains, their work focuses on several subfields, including Molecular Biology, Gastroenterology, Sensory Systems, Cardiology and Cardiovascular Medicine, and Public Health, Environmental and Occupational Health.

The main topics covered by their research include gastrointestinal motility and disorders, ion channels and receptors, ion channel regulation and function, ion transport and channel regulation, cardiac electrophysiology and arrhythmias, receptor mechanisms and signaling, and reproductive biology and fertility.

Sean M. Ward has published extensively, with recent papers including:

  • Oviductal motile cilia are essential for oocyte pickup but dispensable for sperm and embryo transport (2021, Proceedings of the National Academy of Sciences)
  • Ca2+ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the murine colon (2021, eLife)
  • AKAP5 complex facilitates purinergic modulation of vascular L-type Ca2+ channel CaV1.2 (2020, Nature Communications)
  • Propulsive colonic contractions are mediated by inhibition-driven poststimulus responses that originate in interstitial cells of Cajal (2022, Proceedings of the National Academy of Sciences)
  • The identification of neuronal control pathways supplying effector tissues in the stomach (2020, Cell and Tissue Research)

Their research is often published in prominent venues such as The FASEB Journal, Proceedings of the National Academy of Sciences, The Journal of Physiology, American Journal of Physiology-Gastrointestinal and Liver Physiology, and eLife.

Sean M. Ward has collaborated frequently with several coauthors, including Kenton M. Sanders, Sung Jin Hwang, Salah A. Baker, Bernard T. Drumm, and Kent C. Sasse.

Best Publications

  • Mutation of the proto‐oncogene c‐kit blocks development of interstitial cells and electrical rhythmicity in murine intestine.

    S M Ward;A J Burns;S Torihashi;K M Sanders

  • Nitric oxide as a mediator of nonadrenergic noncholinergic neurotransmission.

    K. M. Sanders;S. M. Ward

  • Interstitial cells of cajal as pacemakers in the gastrointestinal tract.

    Kenton M. Sanders;Sang Don Koh;Sean M. Ward

  • Interstitial cells of Cajal mediate inhibitory neurotransmission in the stomach.

    Alan J. Burns;Alan E. J. Lomax;Shigeko Torihashi;Kenton M. Sanders

  • Interstitial Cells of Cajal Mediate Cholinergic Neurotransmission from Enteric Motor Neurons

    Sean M. Ward;Elizabeth A. H. Beckett;XuanYu Wang;Fred Baker

  • Interstitial Cells: Regulators of Smooth Muscle Function

    Kenton M. Sanders;Sean M. Ward;Sang Don Koh

  • Protein annotation and modelling servers at University College London

    Daniel W. A. Buchan;S. M. Ward;Anna E. Lobley;Timothy Nugent

  • Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles

    Sung Jin Hwang;Peter J. A. Blair;Fiona C. Britton;Kate E. O’Driscoll

  • Regulation of gastrointestinal motility—insights from smooth muscle biology

    Kenton M. Sanders;Sang Don Koh;Seungil Ro;Sean M. Ward

  • Remodeling of networks of interstitial cells of Cajal in a murine model of diabetic gastroparesis.

    Tamas Ördög;Ichiro Takayama;Wai Kwok T. Cheung;Sean M. Ward

  • Development and plasticity of interstitial cells of Cajal.

    Kenton M. Sanders;T. Ördög;S. D. Koh;S. Torihashi

  • Blockade of kit signaling induces transdifferentiation of interstitial cells of Cajal to a smooth muscle phenotype

    Shigeko Torihashi;Katsuhide Nishi;Yoshiko Tokutomi;Tetsuo Nishi

  • c-kit-dependent development of interstitial cells and electrical activity in the murine gastrointestinal tract.

    Shigeko Torihashi;Sean M. Ward;Shin-Ichi Nishikawa;Katsuhide Nishi

  • Pacemaking in interstitial cells of Cajal depends upon calcium handling by endoplasmic reticulum and mitochondria

    S. M. Ward;T. Ördög;S. D. Koh;S. Abu Baker

  • Spontaneous electrical rhythmicity in cultured interstitial cells of Cajal from the murine small intestine

    Sang Don Koh;Kenton M. Sanders;Sean M. Ward

  • Interstitial cells of Cajal mediate enteric inhibitory neurotransmission in the lower esophageal and pyloric sphincters.

    Sean M. Ward;Gerard Morris;Lee Reese;Xuan-Yu Wang

  • Impaired development of interstitial cells and intestinal electrical rhythmicity in steel mutants

    S. M. Ward;A. J. Burns;S. Torihashi;S. C. Harney

  • Development of c-Kit-positive cells and the onset of electrical rhythmicity in murine small intestine

    Shigeko Torihashi;Sean M. Ward;Kenton M. Sanders

  • Interstitial cells of Cajal generate electrical slow waves in the murine stomach

    Tamás Ördög;Sean M. Ward;Kenton M. Sanders

  • A Ca2+-activated Cl− conductance in interstitial cells of Cajal linked to slow wave currents and pacemaker activity

    Mei Hong Zhu;Tae Wan Kim;Seungil Ro;Wei Yan

Frequent Co-Authors

Kenton M. Sanders
Kenton M. Sanders University of Nevada Reno
Tamas Ordog
Tamas Ordog Mayo Clinic
Yataro Daigo
Yataro Daigo Shiga University of Medical Science
Nick J. Spencer
Nick J. Spencer Flinders University
John B. Furness
John B. Furness Florey Institute of Neuroscience and Mental Health
Johannes W. Hell
Johannes W. Hell University of California, Davis
Wei Yan
Wei Yan University of Nevada Reno
William T. Gerthoffer
William T. Gerthoffer University of Nevada Reno
Luis F. Santana
Luis F. Santana University of California, Davis
Bruce A.J. Ponder
Bruce A.J. Ponder University of Cambridge

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