World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
11183
World Ranking
12669
National Ranking
5403

Overview

William T. Gerthoffer is affiliated with the University of Nevada Reno in the United States. Their research spans multiple fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Within these fields, they have contributed notably to subfields such as Molecular Biology, Cell Biology, Physiology, Immunology, and Neurology.

Their main research topics focus on various aspects of cell and molecular biology and disease mechanisms. Key topics include:

  • Heat shock proteins research
  • Asthma and respiratory diseases
  • Immune Cell Function and Interaction
  • Calpain Protease Function and Regulation
  • Endoplasmic Reticulum Stress and Disease
  • Eosinophilic Esophagitis
  • Pulmonary Hypertension Research and Treatments

William T. Gerthoffer has coauthored multiple publications alongside several frequent collaborators including Jingti Deng, Catherine Diao, Nadia Maarouf, Matthew Rosin, and Vipul Shrivastava.

Their recent published papers provide insight into their research focus and interdisciplinary approach:

  • Nanoparticle Delivery of Anti-inflammatory LNA Oligonucleotides Prevents Airway Inflammation in a HDM Model of Asthma, 2020, Molecular Therapy - Nucleic Acids
  • HSP25 Vaccination Attenuates Atherogenesis via Upregulation of LDLR Expression, Lowering of PCSK9 Levels and Curbing of Inflammation, 2021, Arteriosclerosis Thrombosis and Vascular Biology
  • Epigenetic Targets for Oligonucleotide Therapies of Pulmonary Arterial Hypertension, 2020, International Journal of Molecular Sciences
  • Heat Shock Protein 27 Immune Complex Upregulates LDLR Expression Thereby Reducing Plasma Cholesterol and Atherogenesis, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Novel in vivo Assessment of Unruptured Intracranial Aneurysm Inflammatory Factors, 2020, Frontiers in Neurology

The scientist's frequent publication venues reflect their interdisciplinary approach, including journals focused on vascular biology, molecular therapy, neurology, and preprint platforms:

  • Arteriosclerosis Thrombosis and Vascular Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Therapy - Nucleic Acids
  • International Journal of Molecular Sciences
  • Frontiers in Neurology

Best Publications

  • Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

    Joe G.N. Garcia;Feng Liu;Alexander D. Verin;Anna Birukova

  • Universal physical responses to stretch in the living cell

    Xavier Trepat;Linhong Deng;Linhong Deng;Steven S. An;Steven S. An;Daniel Navajas

  • Airway smooth muscle dynamics: A common pathway of airway obstruction in asthma

    S S An;T R Bai;J H T Bates;J L Black

  • Mechanisms of Vascular Smooth Muscle Cell Migration

    William T. Gerthoffer

  • A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell Migration

    Jason C. Hedges;Melissa A. Dechert;Ilia A. Yamboliev;Jody L. Martin

  • Invited review: focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle.

    William T. Gerthoffer;Susan J. Gunst

  • Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle.

    Reinoud Gosens;Gerald L Stelmack;Gordon Dueck;Karol D McNeill

  • Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration.

    David S. Weber;Yoshihiro Taniyama;Petra Rocic;Puvi N. Seshiah

  • Phosphorylation of the 27-kDa heat shock protein via p38 MAP kinase and MAPKAP kinase in smooth muscle

    Janice K. Larsen;Ilia A. Yamboliev;Lee A. Weber;William T. Gerthoffer

  • Evidence for modulation of smooth muscle force by the p38 MAP kinase/HSP27 pathway.

    Ilia A. Yamboliev;Jason C. Hedges;Jack L.-M. Mutnick;Leonard P. Adam

  • MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype.

    Andrew R. Kuhn;Karen Schlauch;Ronna Lao;Andrew J. Halayko

  • Mitogen-Activated Protein Kinases Regulate Cytokine Gene Expression in Human Airway Myocytes

    Jason C. Hedges;Cherie A. Singer;William T. Gerthoffer

  • MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle

    Brian S Comer;Blanca Camoretti-Mercado;Paul C. Kogut;Andrew John Halayko

  • Myocardin Is Sufficient for a Smooth Muscle-Like Contractile Phenotype

    Xiaochun Long;Robert D. Bell;William T. Gerthoffer;Berislav V. Zlokovic

  • Small Heat Shock Proteins in Smooth Muscle

    Sonemany Salinthone;Manoj Tyagi;William T. Gerthoffer

  • p38 MAPK and NF-κB mediate COX-2 expression in human airway myocytes

    Cherie A. Singer;Kimberly J. Baker;Alan McCaffrey;David P. AuCoin

  • p21-activated kinase 1 participates in tracheal smooth muscle cell migration by signaling to p38 MAPK

    Melissa A. Dechert;Jennifer M. Holder;William T. Gerthoffer

  • Signal-transduction pathways that regulate visceral smooth muscle function. III. Coupling of muscarinic receptors to signaling kinases and effector proteins in gastrointestinal smooth muscles.

    William T. Gerthoffer

  • Migration of Airway Smooth Muscle Cells

    William T. Gerthoffer

  • Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension

    Jared M. McLendon;Sachindra R. Joshi;Jeff Sparks;Majed Matar

Frequent Co-Authors

Andrew J. Halayko
Andrew J. Halayko University of Manitoba
Kenton M. Sanders
Kenton M. Sanders University of Nevada Reno
Julian Solway
Julian Solway University of Chicago
Ivan F. McMurtry
Ivan F. McMurtry University of South Alabama
Reinoud Gosens
Reinoud Gosens University of Groningen
Jeffrey J. Fredberg
Jeffrey J. Fredberg Harvard University
Johan Zaagsma
Johan Zaagsma University of Groningen
Sean M. Ward
Sean M. Ward University of Nevada Reno
Ben Fabry
Ben Fabry University of Erlangen-Nuremberg
Bernard P. Leung
Bernard P. Leung Singapore Institute of Technology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Biology and Biochemistry opens a wide range of rewarding career opportunities in the expanding healthcare sector. With the rise of remote learning, students now have more flexibility to pursue specialized roles through online programs tailored to the dynamic needs of the industry.

For those interested in health support services, the medical billing and coding outlook is positive, with ongoing demand for professionals adept at handling sensitive patient data and insurance processes. If you are seeking administrative roles in healthcare, it is worth exploring health information management online programs, which combine technology, data management, and patient care.

Those passionate about nutrition can advance their careers and expertise through nutrition masters online, providing a deeper understanding of biochemistry applied to diet and wellness. Additionally, students interested in diagnostic healthcare can consider flexible ultrasound tech programs online that blend scientific knowledge with hands-on skills.

These online degree options not only enhance career prospects but also support work-life balance and accessibility for students everywhere.

Best Scientists Citing William T. Gerthoffer

Trending Scientists

Recently Published Articles