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Medicine

D-Index
82
Citations
21404
World Ranking
16274
National Ranking
8182

Overview

Ivan F. McMurtry is affiliated with the University of South Alabama in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Pulmonary and Respiratory Medicine, Molecular Biology, Surgery, Biomedical Engineering, and Physical and Theoretical Chemistry.

McMurtry's investigation centers around several main topics, including:

  • Pulmonary Hypertension Research and Treatments
  • Epigenetics and DNA Methylation
  • Transplantation: Methods and Outcomes
  • Organ Transplantation Techniques and Outcomes
  • 3D Printing in Biomedical Research
  • Thermodynamics and Calorimetric Analyses
  • PARP Inhibition in Cancer Therapy

Their recent published papers include:

  • Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation (2020), published in the American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Pulmonary-arterial-hypertension (PAH)-on-a-chip: fabrication, validation and application (2020), published in Lab on a Chip
  • Inhibition of Glucose-6-Phosphate Dehydrogenase Activity Attenuates Right Ventricle Pressure and Hypertrophy Elicited by VEGFR Inhibitor + Hypoxia (2021), published in the Journal of Pharmacology and Experimental Therapeutics
  • Pluripotent hematopoietic stem cells augment α-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension (2020), published in the American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Pharmacologic and genetic inhibition of G6PD activity attenuates right ventricle pressure and hypertrophy elicited by hypoxia and VEGF inhibitor+hypoxia (2020), published in Authorea

Frequent co-authors collaborating with McMurtry include:

  • Allan M. Jordan
  • Ian D. Waddell
  • Sachin A. Gupte
  • A. Kitagawa
  • Christina Jacob

McMurtry has consistently published in the following venues:

  • American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Lab on a Chip
  • Journal of Pharmacology and Experimental Therapeutics
  • Authorea

The scope of their work integrates cellular and molecular mechanisms underlying pulmonary hypertension, the use of experimental models such as PAH-on-a-chip technologies, and the inhibition of glucose-6-phosphate dehydrogenase activity to study cardiac and vascular physiology. Their research also explores genetic and pharmacologic methods to modulate disease processes related to hypoxia and vascular function.

Best Publications

  • Cellular and molecular basis of pulmonary arterial hypertension.

    Nicholas W. Morrell;Serge Adnot;Stephen L. Archer;Jocelyn Dupuis

  • Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure

    Kurt R. Stenmark;Barbara Meyrick;Nazzareno Galie;Wolter J. Mooi

  • Formation of plexiform lesions in experimental severe pulmonary arterial hypertension

    Kohtaro Abe;Michie Toba;Abdallah Alzoubi;Masako Ito

  • Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth.

    S. H. Abman;B. A. Chatfield;S. L. Hall;I. F. McMurtry

  • Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs.

    I F McMurtry;A B Davidson;J T Reeves;R F Grover

  • Reperfusion after acute coronary occlusion in dogs impairs endothelium-dependent relaxation to acetylcholine and augments contractile reactivity in vitro.

    K M VanBenthuysen;I F McMurtry;L D Horwitz

  • Granulocytes mediate acute edematous lung injury in rabbits and in isolated rabbit lungs perfused with phorbol myristate acetate: role of oxygen radicals.

    D. Michael Shasby;Karyl M. Vanbenthuysen;Robert M. Tate;Sandra S. Shasby

  • Rho Kinase–Mediated Vasoconstriction Is Important in Severe Occlusive Pulmonary Arterial Hypertension in Rats

    Masahiko Oka;Noriyuki Homma;Laimute Taraseviciene-Stewart;Kenneth G. Morris

  • Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase.

    Karen A. Fagan;Masahiko Oka;Natalie R. Bauer;Sarah A. Gebb

  • The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia

    Karen A. Fagan;Brian W. Fouty;Robert C. Tyler;Kenneth G. Morris

  • Role of endothelin-1 in lung disease

    Karen A Fagan;Ivan F McMurtry;David M Rodman

  • Oxygen-Radical-Mediated Permeability Edema and Vasoconstriction in Isolated Perfused Rabbit Lungs1–4

    Robert M. Tate;Karyl M. Vanbenthuysen;D. Michael Shasby;Ivan F. McMurtry

  • Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension.

    Tetsutaro Nagaoka;Karen A. Fagan;Sarah A. Gebb;Kenneth G. Morris

  • Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats.

    Tetsutaro Nagaoka;Yoshiteru Morio;Nina Casanova;Natalie Bauer

  • Lung vascular smooth muscle as a determinant of pulmonary hypertension at high altitude

    A Tucker;IF McMurtry;JT Reeves;AF Alexander

  • Endothelial cells in culture produce a vasoconstrictor substance.

    Richard F. O'Brien;Richard J. Robbins;Ivan F. McMurtry

  • Sustained coronary vasoconstriction provoked by a peptidergic substance released from endothelial cells in culture.

    M N Gillespie;J O Owasoyo;I F McMurtry;R F O'Brien

  • Effects of birth-related stimuli on L-arginine-dependent pulmonary vasodilation in ovine fetus.

    D. N. Cornfield;B. A. Chatfield;J. A. McQueston;I. F. McMurtry

  • Normalization of nitric oxide production corrects arterial vasodilation and hyperdynamic circulation in cirrhotic rats

    Michel Niederberger;Pierre-Yves Martin;Pere Ginès;Kenneth Morris

  • Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats : Rho GTPases in lung physiology and disease

    Tetsutaro Nagaoka;Yoshiteru Morio;Nina Casanova;Natalie Bauer

Frequent Co-Authors

John T. Reeves
John T. Reeves University of Colorado Anschutz Medical Campus
Steven H. Abman
Steven H. Abman University of Colorado Denver
John E. Repine
John E. Repine University of Colorado Denver
Norbert F. Voelkel
Norbert F. Voelkel Virginia Commonwealth University
Kurt R. Stenmark
Kurt R. Stenmark University of Colorado Anschutz Medical Campus
D. Dunbar Ivy
D. Dunbar Ivy University of Colorado Denver
William T. Gerthoffer
William T. Gerthoffer University of Nevada Reno
Troy Stevens
Troy Stevens University of South Alabama
Robert W. Schrier
Robert W. Schrier University of Colorado Denver
Erkki Ruoslahti
Erkki Ruoslahti Sanford Burnham Prebys Medical Discovery Institute

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