World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
68
Citations
14953
World Ranking
1525
National Ranking
772

Overview

Wei Yan is affiliated with the Lundquist Institute in the United States and has a research profile primarily focused on medicine as well as biochemistry, genetics, and molecular biology. Their work intersects multiple subfields, with a notable emphasis on molecular biology, cancer research, epidemiology, public health, environmental and occupational health, and pediatrics, perinatology, and child health.

The areas of research Wei Yan has contributed to include:

  • MicroRNA in disease regulation
  • Reproductive biology and fertility
  • Epigenetics and DNA methylation
  • Sperm and testicular function
  • Assisted reproductive technology and twin pregnancy
  • RNA modifications and cancer
  • Birth, development, and health

Wei Yan has published extensively in several notable venues. The most frequent publication sources for their work are:

  • Biology of Reproduction
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The American Journal of Gastroenterology
  • Proceedings of the National Academy of Sciences
  • SSRN Electronic Journal

They have collaborated regularly with several researchers, including Zhuqing Wang, Huili Zheng, Shuiqiao Yuan, Yeming Xie, and Hayden McSwiggin, indicating active research partnerships and frequent co-authorship in their field.

Some of Wei Yan's recent papers provide a view into their research topics and scientific contributions:

  • "m6A-dependent biogenesis of circular RNAs in male germ cells," 2020, Cell Research
  • "Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates," 2021, Nature Communications
  • "Oviductal motile cilia are essential for oocyte pickup but dispensable for sperm and embryo transport," 2021, Proceedings of the National Academy of Sciences
  • "Elimination of Calm1 long 3'-UTR mRNA isoform by CRISPR-Cas9 gene editing impairs dorsal root ganglion development and hippocampal neuron activation in mice," 2020, RNA
  • "AASRA: an anchor alignment-based small RNA annotation pipeline†," 2021, Biology of Reproduction

Wei Yan's research emphasizes molecular mechanisms relevant to reproductive biology and fertility, with additional focus in epigenetics and RNA biology. Their work incorporates experimental approaches in genetics and molecular biology techniques, often addressing cellular and developmental processes in mammalian systems.

Best Publications

  • Epigenetic inheritance of acquired traits through sperm RNAs and sperm RNA modifications

    Qi Chen;Wei Yan;Enkui Duan

  • ALKBH5-dependent m6A demethylation controls splicing and stability of long 3′-UTR mRNAs in male germ cells

    Chong Tang;Rachel Klukovich;Hongying Peng;Zhuqing Wang

  • Tissue-dependent paired expression of miRNAs

    Seungil Ro;Chanjae Park;David Young;Kenton M. Sanders

  • Whole-Genome Sequencing Analysis Reveals High Specificity of CRISPR/Cas9 and TALEN-Based Genome Editing in Human iPSCs

    Cory Smith;Athurva Gore;Wei Yan;Leire Abalde-Atristain

  • Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs.

    Yunfang Zhang;Yunfang Zhang;Xudong Zhang;Junchao Shi;Francesca Tuorto

  • A Ca2+-activated Cl− conductance in interstitial cells of Cajal linked to slow wave currents and pacemaker activity

    Mei Hong Zhu;Tae Wan Kim;Seungil Ro;Wei Yan

  • Cloning and expression profiling of testis-expressed microRNAs

    Seungil Ro;Chanjae Park;Kenton M. Sanders;John R. McCarrey

  • TEX14 is essential for intercellular bridges and fertility in male mice

    Michael P. Greenbaum;Wei Yan;Meng-Hsieh Wu;Yi-Nan Lin

  • Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis

    Jingwen Wu;Jianqiang Bao;Minkyung Kim;Shuiqiao Yuan

  • Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development.

    Shuiqiao Yuan;Andrew Schuster;Chong Tang;Tian Yu

  • Loss of Zona Pellucida Binding Proteins in the Acrosomal Matrix Disrupts Acrosome Biogenesis and Sperm Morphogenesis

    Yi Nan Lin;Angshumoy Roy;Wei Yan;Kathleen H. Burns

  • MicroRNA-449 and MicroRNA-34b/c Function Redundantly in Murine Testes by Targeting E2F Transcription Factor-Retinoblastoma Protein (E2F-pRb) Pathway

    Jianqiang Bao;Ding Li;Li Wang;Jingwen Wu

  • Stem cell factor protects germ cells from apoptosis in vitro.

    Wei Yan;Janne Suominen;Jorma Toppari

  • Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation.

    Xiaosong Huang;Ying Wang;Wei Yan;Cory Smith

  • Cloning and expression profiling of small RNAs expressed in the mouse ovary

    Seungil Ro;Rui Song;Chanjae Park;Huili Zheng

  • Male infertility caused by spermiogenic defects: lessons from gene knockouts.

    Wei Yan

  • HILS1 is a spermatid-specific linker histone H1-like protein implicated in chromatin remodeling during mammalian spermiogenesis.

    Wei Yan;Lang Ma;Kathleen H. Burns;Martin M. Matzuk

  • Many X-linked microRNAs escape meiotic sex chromosome inactivation

    Rui Song;Seungil Ro;Jason D Michaels;Chanjae Park

  • The RNase III Enzyme DROSHA Is Essential for MicroRNA Production and Spermatogenesis

    Qiuxia Wu;Rui Song;Nicole Ortogero;Huili Zheng

  • Sertoli cell Dicer is essential for spermatogenesis in mice.

    Marilena D. Papaioannou;Jean-Luc Pitetti;Seungil Ro;Chanjae Park

Frequent Co-Authors

Martin M. Matzuk
Martin M. Matzuk Baylor College of Medicine
Jorma Toppari
Jorma Toppari University of Turku
Kenton M. Sanders
Kenton M. Sanders University of Nevada Reno
Kathleen H. Burns
Kathleen H. Burns Harvard University
John R. McCarrey
John R. McCarrey The University of Texas at San Antonio
Michael K. Skinner
Michael K. Skinner Washington State University
Olli A. Jänne
Olli A. Jänne University of Helsinki
Aleksandar Rajkovic
Aleksandar Rajkovic University of California, San Francisco
Ryuzo Yanagimachi
Ryuzo Yanagimachi University of Hawaii at Manoa
Sean M. Ward
Sean M. Ward University of Nevada Reno

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