World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
14764
World Ranking
5756
National Ranking
135

Overview

Moira K O'Bryan is affiliated with the University of Melbourne in Australia, with a research focus spanning medicine and biochemistry, genetics, and molecular biology. Their work predominantly intersects reproductive medicine, molecular biology, public health, genetics, and cell biology.

Their main research topics include:

  • Sperm and testicular function
  • Reproductive biology and fertility
  • Genetic and clinical aspects of sex determination and chromosomal abnormalities
  • Microtubule and mitosis dynamics
  • CRISPR and genetic engineering
  • Chromosomal and genetic variations
  • Micro and nano robotics

O'Bryan has published extensively, with major contributions appearing in venues such as bioRxiv (Cold Spring Harbor Laboratory), Human Reproduction, Nature Communications, Human Reproduction Update, and Nature Reviews Urology. These platforms collectively reflect the scientist's concentration on reproductive biology and related genetic studies.

Their recent notable papers include:

  • "Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials" (2021) - Nature Microbiology
  • "A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene-disease relationships" (2021) - Human Reproduction Update
  • "Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility" (2021) - The American Journal of Human Genetics
  • "A de novo paradigm for male infertility" (2022) - Nature Communications
  • "Haploid male germ cells-the Grand Central Station of protein transport" (2020) - Human Reproduction Update

Frequent collaborators documented alongside O'Bryan include Brendan J. Houston, Jessica E. M. Dunleavy, Anne E. O'Connor, Donald F. Conrad, and D. Jo Merriner. These coauthors collectively contribute to a body of work focused on reproductive health and genetics.

The scientist's research aligns closely with understanding male infertility and the genetic, molecular, and cellular mechanisms involved in reproductive function. The work reflects a blend of fundamental biological studies and applied medical research relevant to fertility and associated genetic conditions.

Best Publications

  • The CAP Superfamily: Cysteine-Rich Secretory Proteins, Antigen 5, and Pathogenesis-Related 1 Proteins—Roles in Reproduction, Cancer, and Immune Defense

    Gerard Mark Gibbs;Kim Roelants;Moira Kathleen O'Bryan;Moira Kathleen O'Bryan

  • Spermiation: The process of sperm release.

    Liza O'Donnell;Peter K. Nicholls;Moira K. O’Bryan;Robert I. McLachlan

  • Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis

    Kylie E Webster;Moira Kathleen O'Bryan;Stephen Fletcher;Pauline E Crewther

  • The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis.

    Gabrielle C Douglas;Moira K O'Bryan;Mark Peter Hedger;David K L Lee

  • Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials.

    Fernando Gordillo Altamirano;John H Forsyth;Ruzeen Patwa;Xenia Kostoulias

  • Immunohistochemical localization of endothelial nitric oxide synthase in human testis, epididymis, and vas deferens suggests a possible role for nitric oxide in spermatogenesis, sperm maturation, and programmed cell death.

    Armand Zini;Armand Zini;Moira K. O'Bryan;Margret S. Magid;Peter N. Schlegel;Peter N. Schlegel

  • Bacterial lipopolysaccharide-induced inflammation compromises testicular function at multiple levels in vivo.

    Moira K O'Bryan;Stefan Schlatt;David James Phillips;David M de Kretser

  • Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring.

    A.K. Short;K.A. Fennell;K.A. Fennell;Victoria M Perreau;A. Fox

  • State of the Art for Genetic Testing of Infertile Men

    Robert I McLachlan;Moira Kathleen O'Bryan

  • Regulation of germ cell and Sertoli cell development by activin, follistatin, and FSH.

    Terri Meehan;Stefan Schlatt;Moira K. O'Bryan;David M. de Kretser

  • Microtubules and spermatogenesis.

    Liza O'Donnell;Moira Kathleen O'Bryan

  • Modifiers of epigenetic reprogramming show paternal effects in the mouse

    Suyinn Chong;Nicola Vickaryous;Alyson Ashe;Natasha Marie Zamudio

  • Developmental Expression of Thyroid Hormone Receptors in the Rat Testis

    Jeremy J. Buzzard;John R. Morrison;Moira K. O'Bryan;Qing Song

  • Inducible Nitric Oxide Synthase in the Rat Testis: Evidence for Potential Roles in Both Normal Function and Inflammation-Mediated Infertility

    Moira K O'Bryan;Stefan Schlatt;Orapin Gerdprasert;David James Phillips

  • A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene-disease relationships.

    Brendan J Houston;Antoni Riera-Escamilla;Margot J Wyrwoll;Albert Salas-Huetos;Albert Salas-Huetos

  • Fat Aussie—A New Alström Syndrome Mouse Showing a Critical Role for ALMS1 in Obesity, Diabetes, and Spermatogenesis

    Todor Arsov;Diego G. Silva;Moira K. O’Bryan;Amanda Sainsbury

  • Human seminal clusterin (SP-40,40). Isolation and characterization

    M. K. O'bryan;H. W. G. Baker;J. R. Saunders;L. Kirszbaum

  • The Cysteine-rich Secretory Protein Domain of Tpx-1 Is Related to Ion Channel Toxins and Regulates Ryanodine Receptor Ca2+ Signaling

    Gerard Mark Gibbs;Martin J Scanlon;James David Swarbrick;Suzanne Curtis

  • The Identification of Mouse Sperm-Surface-Associated Proteins and Characterization of Their Ability to Act as Decapacitation Factors

    Brett Nixon;David A. MacIntyre;David A. MacIntyre;Lisa A. Mitchell;Gerard M. Gibbs

  • Cellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction.

    Leanne Maree Cotton;Moira Kathleen O'Bryan;Barry T Hinton

Frequent Co-Authors

D. M. de Kretser
D. M. de Kretser Monash University
Robert I McLachlan
Robert I McLachlan Monash University
Mark P. Hedger
Mark P. Hedger Hudson Institute of Medical Research
Christopher C. Goodnow
Christopher C. Goodnow Garvan Institute of Medical Research
Joris A. Veltman
Joris A. Veltman University of Edinburgh
Kate L Loveland
Kate L Loveland Hudson Institute of Medical Research
R. John Aitken
R. John Aitken University of Newcastle Australia
Brett Nixon
Brett Nixon University of Newcastle Australia
Hamish S. Scott
Hamish S. Scott University of Adelaide
Eileen A. McLaughlin
Eileen A. McLaughlin University of Wollongong

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Moira K O'Bryan

Trending Scientists