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Biology and Biochemistry
China
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
106
Citations
34587
World Ranking
1164
National Ranking
690

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in China Leader Award

Overview

C. Yan Cheng is affiliated with Wenzhou Medical University in China and focuses their research on areas within medicine and biochemistry, genetics, and molecular biology. Their scientific contributions emphasize reproductive medicine and molecular biology, with additional work impacting public health, environmental and occupational health, genetics, and cell biology.

Their research topics prominently cover sperm and testicular function, reproductive biology and fertility, genetic and clinical aspects of sex determination and chromosomal abnormalities, microtubule and mitosis dynamics, epigenetics and DNA methylation, renal and related cancers, and testicular diseases and treatments.

Frequent coauthors who have collaborated extensively with C. Yan Cheng include:

  • Fei Sun
  • Xiaolong Wu
  • Lingling Wang
  • Tiao Bu
  • Linxi Li

They have published numerous papers in prominent venues including:

  • Advances in Experimental Medicine and Biology
  • Endocrinology
  • Seminars in Cell and Developmental Biology
  • Frontiers in Immunology
  • The FASEB Journal

Representative papers from their recent research include:

  • Dissecting mammalian spermatogenesis using spatial transcriptomics, 2021, Cell Reports
  • Sperm epigenetic alterations contribute to inter- and transgenerational effects of paternal exposure to long-term psychological stress via evading offspring embryonic reprogramming, 2021, Cell Discovery
  • Whole-exome sequencing of a large Chinese azoospermia and severe oligospermia cohort identifies novel infertility causative variants and genes, 2020, Human Molecular Genetics
  • Reorganized 3D Genome Structures Support Transcriptional Regulation in Mouse Spermatogenesis, 2020, iScience
  • Human obstructive (postvasectomy) and nonobstructive azoospermia - Insights from scRNA-Seq and transcriptome analysis, 2020, Genes & Diseases

Best Publications

  • Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis

    Dolores D. Mruk;C. Yan Cheng

  • The Blood-Testis Barrier and Its Implications for Male Contraception

    C. Yan Cheng;Dolores D. Mruk

  • Cell Junction Dynamics in the Testis: Sertoli-Germ Cell Interactions and Male Contraceptive Development

    C. Yan Cheng;Dolores D. Mruk

  • The Mammalian Blood-Testis Barrier: Its Biology and Regulation

    Dolores D. Mruk;C. Yan Cheng

  • Cadmium-induced testicular injury.

    Erica R. Siu;Dolores D. Mruk;Catarina S. Porto;C. Yan Cheng

  • Antioxidant superoxide dismutase - a review: its function, regulation in the testis, and role in male fertility.

    Dolores D. Mruk;Bruno Silvestrini;Meng-yun Mo;C.Yan Cheng

  • A local autocrine axis in the testes that regulates spermatogenesis

    C. Yan Cheng;Dolores D. Mruk

  • The Interplay of Collagen IV, Tumor Necrosis Factor-α, Gelatinase B (Matrix Metalloprotease-9), and Tissue Inhibitor of Metalloproteases-1 in the Basal Lamina Regulates Sertoli Cell-Tight Junction Dynamics in the Rat Testis

    Michelle K. Y. Siu;Will M. Lee;C. Yan Cheng

  • Impacts of environmental toxicants on male reproductive dysfunction

    Elissa W.P. Wong;C. Yan Cheng

  • Blood-testis barrier dynamics are regulated by testosterone and cytokines via their differential effects on the kinetics of protein endocytosis and recycling in Sertoli cells

    Helen H. N. Yan;Dolores D. Mruk;Will M. Lee;C. Yan Cheng

  • Enhanced chemiluminescence (ECL) for routine immunoblotting: An inexpensive alternative to commercially available kits.

    Dolores D. Mruk;C. Yan Cheng

  • Regulation of blood-testis barrier dynamics: an in vivo study

    Ching-hang Wong;Dolores D. Mruk;Wing-yee Lui;C. Yan Cheng

  • Is cadmium chloride-induced inter-sertoli tight junction permeability barrier disruption a suitable in vitro model to study the events of junction disassembly during spermatogenesis in the rat testis?

    Nancy P. Y. Chung;C. Yan Cheng

  • The blood-testis barrier: its biology, regulation, and physiological role in spermatogenesis.

    Ching-Hang Wong;C Yan Cheng

  • Adhering junction dynamics in the testis are regulated by an interplay of β1-integrin and focal adhesion complex-associated proteins

    Michelle K. Y. Siu;Dolores D. Mruk;Will M. Lee;C. Yan Cheng

  • Interactions of Proteases, Protease Inhibitors, and the β1 Integrin/Laminin γ3 Protein Complex in the Regulation of Ectoplasmic Specialization Dynamics in the Rat Testis

    Michelle K.Y. Siu;C. Yan Cheng

  • Sertoli-Germ Cell Anchoring Junction Dynamics in the Testis Are Regulated by an Interplay of Lipid and Protein Kinases

    Michelle K.Y. Siu;Ching-hang Wong;Will M. Lee;C. Yan Cheng

  • Dynamic cross‐talk between cells and the extracellular matrix in the testis

    Michelle K.Y. Siu;C. Yan Cheng

  • Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis.

    Elissa W.P. Wong;Dolores D. Mruk;C. Yan Cheng

  • Tumor necrosis factor {alpha} reversibly disrupts the blood-testis barrier and impairs Sertoli-germ cell adhesion in the seminiferous epithelium of adult rat testes.

    Michelle W M Li;Weiliang Xia;Dolores D Mruk;Claire Q F Wang

Frequent Co-Authors

Dolores D. Mruk
Dolores D. Mruk Population Council
Will M. Lee
Will M. Lee University of Hong Kong
Chris K.C. Wong
Chris K.C. Wong Hong Kong Baptist University
Weiliang Xia
Weiliang Xia Shanghai Jiao Tong University
Luciano Saso
Luciano Saso Sapienza University of Rome
Moira K O'Bryan
Moira K O'Bryan University of Melbourne
Marco G. Alves
Marco G. Alves University of Aveiro
Peter N. Schlegel
Peter N. Schlegel Cornell University
Mário Sousa
Mário Sousa University of Porto
Yun-Gui Yang
Yun-Gui Yang Chinese Academy of Sciences

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