World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
88
Citations
24822
World Ranking
1180
National Ranking
13

Medicine

D-Index
88
Citations
24822
World Ranking
13287
National Ranking
162

Overview

Kris Thielemans is affiliated with Vrije Universiteit Brussel in Belgium. Their research focuses primarily on medicine, immunology and microbiology, as well as biochemistry, genetics, and molecular biology.

The scientist's main fields of study cover the following areas:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Within these, Thielemans has contributed significantly to several subfields, including:

  • Immunology
  • Oncology
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging
  • Infectious Diseases

The core topics of their work are largely centered on immunotherapy and related mechanisms:

  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • RNA Interference and Gene Delivery
  • Immune Cell Function and Interaction
  • RNA and protein synthesis mechanisms
  • Vaccines and immunoinformatics approaches

Thielemans has published numerous papers, some of the recent ones include:

  • Functional Th1-oriented T follicular helper cells that infiltrate human breast cancer promote effective adaptive immunity, 2021, Journal of Clinical Investigation
  • TriMix and tumor antigen mRNA electroporated dendritic cell vaccination plus ipilimumab: link between T-cell activation and clinical responses in advanced melanoma, 2020, Journal for ImmunoTherapy of Cancer
  • Challenges in neoantigen-directed therapeutics, 2022, Cancer Cell
  • Trial watch: Dendritic cell (DC)-based immunotherapy for cancer, 2022, OncoImmunology
  • Neo-Antigen mRNA Vaccines, 2020, Vaccines

Frequent co-authors collaborating with Kris Thielemans include:

  • Karine Breckpot
  • Lorenzo Franceschini
  • Arthur Esprit
  • Hanne Locy
  • Wout de Mey

The scientist's published work appears in a range of journals, with multiple publications in:

  • Frontiers in Immunology
  • Vaccines
  • Molecular Therapy - Nucleic Acids
  • Journal of Clinical Investigation
  • Journal for ImmunoTherapy of Cancer

Best Publications

  • CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo.

    Roberto Maldonado-López;Thibaut De Smedt;Patrick Michel;Jacques Godfroid

  • Clinical Significance of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia

    Cavé H;van der Werff ten Bosch J;Suciu S;Guidal C

  • Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation

    Bart N. Lambrecht;Marijke De Veerman;Anthony J. Coyle;Jose-Carlos Gutierrez-Ramos

  • A clinical trial of anti-idiotype therapy for B cell malignancy.

    Timothy C. Meeker;James Lowder;David G. Maloney;Richard A. Miller

  • Clearance of influenza virus from the lung depends on migratory langerin+CD11b− but not plasmacytoid dendritic cells

    Corine H. GeurtsvanKessel;Monique A.M. Willart;Leonie S. van Rijt;Femke Muskens

  • Lung-resident eosinophils represent a distinct regulatory eosinophil subset

    Claire Mesnil;Stéfanie Raulier;Geneviève Paulissen;Xue Xiao

  • Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation

    M. H. C. Bakkus;C. Heirman;I. Van Riet;B. Van Camp

  • Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas

    Guoying Zhou;Dave Sprengers;Patrick P.C. Boor;Michail Doukas

  • Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo.

    VéRonique Flamand;Thierry Sornasse;Kris Thielemans;Christian Demanet

  • The B-cell surface protein CD72/Lyb-2 is the ligand for CD5.

    Hilde Van de Velde;Ilka von Hoegen;Wei Luo;Jane R. Parnes

  • Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects

    Christophe Borg;Magali Terme;Julien Taïeb;Cédric Ménard

  • Interleukin-10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin-4 and granulocyte/macrophage-colony-stimulating factor

    Christel Buelens;Valérie Verhasselt;Donat De Groote;Kris M. Thielemans

  • Identification of MAGE-3 Epitopes Presented by HLA-DR Molecules to CD4+ T Lymphocytes

    Pascal Chaux;Valérie Vantomme;Vincent Stroobant;Kris Thielemans

  • B Lymphocytes Regulate Dendritic Cell (Dc) Function in Vivo: Increased Interleukin 12 Production by DCs from B Cell–Deficient Mice Results in T Helper Cell Type 1 Deviation

    Véronique Moulin;Fabienne Andris;Kris M. Thielemans;Charles Maliszewski

  • Immunomodulation of the Tumor Microenvironment: Turn Foe Into Friend

    Hanne Locy;Sven de Mey;Wout de Mey;Mark De Ridder

  • Phase II Study of Autologous Monocyte-Derived mRNA Electroporated Dendritic Cells (TriMixDC-MEL) Plus Ipilimumab in Patients With Pretreated Advanced Melanoma

    Sofie Wilgenhof;Jurgen Corthals;Carlo Heirman;Nicolas van Baren

  • CD83 expression on dendritic cells and T cells: correlation with effective immune responses.

    Cindy Aerts-Toegaert;Carlo Heirman;Sandra Tuyaerts;Jurgen Corthals

  • Genes encoding tumor-specific antigens are expressed in human myeloma cells

    N. Van Baren;F. Brasseur;D. Godelaine;G. Hames

  • Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules.

    Aude Bonehill;Carlo Heirman;Sandra Tuyaerts;Annelies Michiels

  • Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients

    Aude Bonehill;An M.T. Van Nuffel;Jurgen Corthals;Sandra Tuyaerts

  • Human dendritic cell responses to lipopolysaccharide and CD40 ligation are differentially regulated by interleukin-10

    Christel Buelens;Valérie Verhasselt;Donat De Groote;Kris Thielemans

Frequent Co-Authors

Carlo Heirman
Carlo Heirman Vrije Universiteit Brussel
Karine Breckpot
Karine Breckpot Vrije Universiteit Brussel
Muriel Moser
Muriel Moser Université Libre de Bruxelles
Oberdan Leo
Oberdan Leo Université Libre de Bruxelles
Pierre van der Bruggen
Pierre van der Bruggen Université Catholique de Louvain
Michel Goldman
Michel Goldman Université Libre de Bruxelles
Jacques Urbain
Jacques Urbain Université Libre de Bruxelles
Vincent Stroobant
Vincent Stroobant Ludwig Cancer Research
Thierry Boon
Thierry Boon Ludwig Cancer Research
Francis Brasseur
Francis Brasseur Ludwig Cancer Research

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