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Vincent Stroobant

Vincent Stroobant

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
13559
World Ranking
14279
National Ranking
257

Overview

Vincent Stroobant is affiliated with Ludwig Cancer Research in Belgium. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience, with a particular focus on Molecular Biology and Immunology among related subfields.

Their work covers a range of topics, including:

  • Tryptophan and brain disorders
  • Interferon and immune responses
  • Ubiquitin and proteasome pathways
  • Protein kinase regulation and GTPase signaling
  • Bipolar disorder and treatment
  • Gut microbiota and health
  • Stress responses and cortisol

Vincent Stroobant has contributed to multiple research articles published in journals such as the Journal for ImmunoTherapy of Cancer, Scientific Reports, Proceedings of the National Academy of Sciences, and the Journal of Medicinal Chemistry. Notable papers include:

  • "Systemic tryptophan homeostasis" (2022), Frontiers in Molecular Biosciences
  • "Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes" (2023), Journal for ImmunoTherapy of Cancer
  • "Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins" (2020), Scientific Reports
  • "A case of convergent evolution: Several viral and bacterial pathogens hijack RSK kinases through a common linear motif" (2022), Proceedings of the National Academy of Sciences
  • "Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase" (2021), Journal of Medicinal Chemistry

Their frequent co-authors include Benoît J. Van den Eynde, Luc Pilotte, Simon Klaessens, Etienne De Plaen, and Nathalie Vigneron, reflecting collaborative efforts within related domains of study.

Vincent Stroobant's publications appear regularly in venues such as:

  • Journal for ImmunoTherapy of Cancer
  • Scientific Reports
  • Proceedings of the National Academy of Sciences
  • Journal of Medicinal Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Mass Spectrometry: Principles and Applications

    Edmond de Hoffmann;Jean Joseph Charette;Vincent Stroobant;Julie Trottier

  • Tumor-specific shared antigenic peptides recognized by human T cells

    Pierre van der Bruggen;Yi Zhang;Pascal Chaux;Vincent Stroobant

  • An Antigenic Peptide Produced by Peptide Splicing in the Proteasome

    Nathalie Vigneron;Vincent Stroobant;Jacques Chapiro;Annie Ooms

  • Identification of MAGE-3 Epitopes Presented by HLA-DR Molecules to CD4+ T Lymphocytes

    Pascal Chaux;Valérie Vantomme;Vincent Stroobant;Kris Thielemans

  • A new class of phosphotransferases phosphorylated on an aspartate residue in an amino-terminal DXDX(T/V) motif.

    Jean-François Collet;Vincent Stroobant;Michel Pirard;Ghislain Delpierre

  • Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules

    Benoît Guillaume;Jacques Chapiro;Vincent Stroobant;Didier Colau

  • Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes.

    Nathalie Demotte;Nathalie Demotte;Vincent Stroobant;Vincent Stroobant;Pierre J. Courtoy;Patrick Van Der Smissen

  • Antigen Spreading Contributes to MAGE Vaccination-Induced Regression of Melanoma Metastases

    Véronique Corbière;Jacques Chapiro;Vincent Stroobant;Wenbin Ma

  • Database of T cell-defined human tumor antigens: the 2013 update.

    Nathalie Vigneron;Vincent Stroobant;Vincent Stroobant;Benoît J. Van den Eynde;Benoît J. Van den Eynde;Pierre van der Bruggen;Pierre van der Bruggen

  • Blockade of Interleukin-12 Function by Protein Vaccination Attenuates Atherosclerosis

    A.D. Hauer;C. Uyttenhove;P. de Vos;V. Stroobant

  • Molecular Identification of Carnosine Synthase as ATP-grasp Domain-containing Protein 1 (ATPGD1)

    Jakub Drozak;Maria Veiga-da-Cunha;Didier Vertommen;Vincent Stroobant

  • Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators

    Eduard Dolusic;Pierre Larrieu;Laurence Moineaux;Vincent Stroobant

  • Destructive cleavage of antigenic peptides either by the immunoproteasome or by the standard proteasome results in differential antigen presentation.

    Jacques Chapiro;Stéphane Claverol;Fanny Piette;Wenbin Ma

  • Identification of Five MAGE-A1 Epitopes Recognized by Cytolytic T Lymphocytes Obtained by In Vitro Stimulation with Dendritic Cells Transduced with MAGE-A1

    P. Chaux;R. Luiten;N. Demotte;V. Vantomme

  • Rational design of indoleamine 2,3-dioxygenase inhibitors

    Ute F. Röhrig;Ute F. Röhrig;Loay Awad;Loay Awad;Aurélien Grosdidier;Pierre Larrieu;Pierre Larrieu

  • Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase.

    Ghislain Delpierre;Mark H. Rider;Francois Collard;Vincent Stroobant

  • Rational Design of 4-Aryl-1,2,3-Triazoles for Indoleamine 2,3-Dioxygenase 1 Inhibition

    Ute F. Röhrig;Ute F. Röhrig;Somi Reddy Majjigapu;Somi Reddy Majjigapu;Aurélien Grosdidier;Sylvian Bron;Sylvian Bron

  • Constitutive IDO1 Expression in Human Tumors Is Driven by Cyclooxygenase-2 and Mediates Intrinsic Immune Resistance.

    Marc Hennequart;Marc Hennequart;Luc Pilotte;Luc Pilotte;Stefania Cane;Stefania Cane;Delia Hoffmann;Delia Hoffmann

  • An antigenic peptide produced by reverse splicing and double asparagine deamidation

    Alexandre Dalet;Paul F. Robbins;Vincent Stroobant;Nathalie Vigneron

  • Reversal of Tumoral Immune Resistance by Inhibition of Tryptophan 2,3-Dioxygenase (TDO): Design, Synthesis and Preclinical Evaluation of a Novel TDO Inhibitor.

    Eduard Dolušić;Pierre Larrieu;Laurence Moineaux;Vincent Stroobant

Frequent Co-Authors

Benoît Van den Eynde
Benoît Van den Eynde Ludwig Cancer Research
Pierre van der Bruggen
Pierre van der Bruggen Université Catholique de Louvain
Emile Van Schaftingen
Emile Van Schaftingen Université Catholique de Louvain
Thierry Boon
Thierry Boon Ludwig Cancer Research
Johan Wouters
Johan Wouters University of Namur
Laurence Lins
Laurence Lins Gembloux Agro-Bio Tech
Moreno Galleni
Moreno Galleni University of Liège
Jean-François Collet
Jean-François Collet Université Catholique de Louvain
Kris Thielemans
Kris Thielemans Vrije Universiteit Brussel
Catherine Uyttenhove
Catherine Uyttenhove Ludwig Cancer Research

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