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Catherine Uyttenhove

Catherine Uyttenhove

D-Index & Metrics

Immunology

D-Index
54
Citations
15569
World Ranking
3845
National Ranking
57

Overview

Catherine Uyttenhove is affiliated with Ludwig Cancer Research in Belgium. Their research primarily focuses on the biochemical and molecular mechanisms underlying cancer, with significant intersections in immunology and medicine. The scientist's work spans several main fields of study including Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. They have contributed to subfields such as Molecular Biology, Immunology, Immunology and Allergy, Oncology, and Pulmonary and Respiratory Medicine.

The main topics addressed in their research include:

  • TGF-β signaling in diseases
  • Cell Adhesion Molecules Research
  • Cancer-related gene regulation
  • Cancer Cells and Metastasis
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction

Their recent publications highlight a focus on immune modulation and cancer therapy strategies. Key papers include:

  • "TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism," 2021, Journal for ImmunoTherapy of Cancer
  • "Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of cancer," 2021, Communications Biology
  • "Novel antibodies that selectively block mouse IL-12 enable the re-evaluation of the role of IL-12 in immune protection and pathology," 2021, European Journal of Immunology
  • "Lactate dehydrogenase-elevating virus enhances natural killer cell-mediated immunosurveillance of mouse mesothelioma development," 2020, Infectious Agents and Cancer
  • "567 Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of stroma poor cancers," 2021, Regular and Young Investigator Award Abstracts

Frequent co-authors in their publications include:

  • Jacques Van Snick
  • Aditi Gupta
  • Sadna Budhu
  • Rachel Giese
  • Adam O. Michel

Their research outputs have appeared across a variety of publication venues such as:

  • Journal for ImmunoTherapy of Cancer
  • Communications Biology
  • European Journal of Immunology
  • Infectious Agents and Cancer
  • Regular and Young Investigator Award Abstracts

Best Publications

  • Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

    Catherine Uyttenhove;Luc Pilotte;Ivan Théate;Ivan Théate;Vincent Stroobant

  • Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset

    Marc Veldhoen;Catherine Uyttenhove;Jacques van Snick;Helena Helmby

  • IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

    Wassim Elyaman;Elizabeth M. Bradshaw;Catherine Uyttenhove;Valérie Dardalhon

  • Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

    David Bending;Hugo De La Peña;Marc Veldhoen;Jenny M. Phillips

  • Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

    Luc Pilotte;Pierre Larrieu;Vincent Stroobant;Didier Colau

  • B cell depletion reduces the development of atherosclerosis in mice

    Hafid Ait-Oufella;Olivier Herbin;Jean-David Bouaziz;Jean-David Bouaziz;Christoph J. Binder

  • Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

    Soraya Taleb;Mélissa Romain;Bhama Ramkhelawon;Catherine Uyttenhove

  • Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity

    C Uyttenhove;R J Simpson;J Van Snick

  • Mast cell growth-enhancing activity (MEA) is structurally related and functionally identical to the novel mouse T cell growth factor P40/TCGFIII (interleukin 9).

    Lothar Hültner;Catherine Druez;Jochen Moeller;Catherine Uyttenhove

  • Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression.

    Catherine Uyttenhove;Janet Maryanski;Thierry Boon

  • T cell growth and differentiation induced by interleukin-HP1/IL-6, the murine hybridoma/plasmacytoma growth factor.

    C Uyttenhove;P G Coulie;J Van Snick

  • Genes coding for tumor-antigens recognized by cytolytic T-lymphocytes

    Aline Van Pel;Pierre Van Der Bruggen;Pierre G. Coulie;Vincent G. Brichard

  • Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes.

    Jingjing Zhu;Jingjing Zhu;Céline G. Powis de Tenbossche;Céline G. Powis de Tenbossche;Stefania Cané;Stefania Cané;Didier Colau;Didier Colau

  • Expression cloning of the murine and human interleukin 9 receptor cDNAs.

    J C Renauld;C Druez;A Kermouni;F Houssiau

  • Blockade of Interleukin-12 Function by Protein Vaccination Attenuates Atherosclerosis

    A.D. Hauer;C. Uyttenhove;P. de Vos;V. Stroobant

  • Cloning and Characterization of a Cdna for a New Mouse T-cell Growth-factor (p40)

    J Van Snick;A Goethals;J C Renauld;E Van Roost

  • A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9.

    J B Demoulin;C Uyttenhove;E Van Roost;B DeLestré

  • Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. II. T lymphocyte-mediated cytolysis.

    T Boon;J Van Snick;A Van Pel;C Uyttenhove

  • Development of an anti-IL-17A auto-vaccine that prevents experimental auto-immune encephalomyelitis.

    Catherine Uyttenhove;Jacques Van Snick;Jacques Van Snick

  • IL-6 Inhibits the Tolerogenic Function of CD8α+ Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase

    Ursula Grohmann;Francesca Fallarino;Roberta Bianchi;Maria Laura Belladonna

  • Purification and NH2-terminal Amino-acid-sequence of a New T-cell Derived Lymphokine With Growth-factor Activity for B-cell Hybridomas

    Jacques Van Snick;S. Cayphas;A. Vink;Catherine Uyttenhove

Frequent Co-Authors

Jacques Van Snick
Jacques Van Snick Université Catholique de Louvain
Thierry Boon
Thierry Boon Ludwig Cancer Research
Jean-Christophe Renauld
Jean-Christophe Renauld Université Catholique de Louvain
Benoît Van den Eynde
Benoît Van den Eynde Ludwig Cancer Research
J Van Snick
J Van Snick Université Catholique de Louvain
Pierre Coulie
Pierre Coulie Université Catholique de Louvain
Bernhard Ryffel
Bernhard Ryffel University of Orléans
Francesca Fallarino
Francesca Fallarino University of Perugia
Vincent Stroobant
Vincent Stroobant Ludwig Cancer Research
Laure Dumoutier
Laure Dumoutier Université Catholique de Louvain

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