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Roberta Bianchi

Roberta Bianchi

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
19266
World Ranking
10583
National Ranking
300

Overview

Roberta Bianchi is affiliated with the University of Perugia in Italy and has contributed to research primarily in the fields of Medicine, Biochemistry, Genetics, and Molecular Biology. Their work spans several specialized subfields including Oncology, Immunology, Pathology and Forensic Medicine, Molecular Biology, and Cancer Research.

The scientist's research focuses on multiple main topics, such as:

  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Lymphoma Diagnosis and Treatment
  • Angiogenesis and VEGF in Cancer
  • Cancer, Hypoxia, and Metabolism
  • Lipid metabolism and disorders
  • Cancer, Stress, Anesthesia, and Immune Response

Bianchi has published papers in notable venues including Clinical Cancer Research, Journal of Clinical Investigation, and Cancer Research. Some recent publications include:

  • "Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice," 2020, Journal of Clinical Investigation
  • "Dissecting the Mechanisms Underlying the Cytokine Release Syndrome (CRS) Mediated by T-Cell Bispecific Antibodies," 2023, Clinical Cancer Research
  • "Abstract ND08: FAP-LTBR (RO7567132): a first-in-class bi-specific stromal immunomodulatory agonist designed to enable and enhance efficacy of cancer immunotherapies," 2025, Cancer Research

Frequent collaborators include Sina Nassiri, Pablo Umaña, Gabrielle Leclercq-Cohen, Nathalie Steinhoff, and Llucia Albertí Servera. The number of joint publications ranges mainly from one to two with these coauthors.

Bianchi's contributions intersect interdisciplinary areas related to both basic molecular research and clinical applications with an emphasis on cancer immunotherapy, tumor microenvironment, and immune-related adverse effects associated with advanced therapies.

This profile summarizes the areas of study, collaboration networks, and publication history underpinning Roberta Bianchi's academic output within the biomedical research community.

Best Publications

  • Modulation of tryptophan catabolism by regulatory T cells.

    Francesca Fallarino;Ursula Grohmann;Kwang Woo Hwang;Ciriana Orabona

  • CTLA-4-Ig regulates tryptophan catabolism in vivo.

    Ursula Grohmann;Ciriana Orabona;Francesca Fallarino;Carmine Vacca

  • The Combined Effects of Tryptophan Starvation and Tryptophan Catabolites Down-Regulate T Cell Receptor ζ-Chain and Induce a Regulatory Phenotype in Naive T Cells

    Francesca Fallarino;Ursula Grohmann;Sylvaine You;Barbara C. McGrath

  • T cell apoptosis by tryptophan catabolism.

    Francesca Fallarino;Ursula Grohmann;Carmine Vacca;Roberta Bianchi

  • S100B's double life: Intracellular regulator and extracellular signal

    Rosario Donato;Guglielmo Sorci;Francesca Riuzzi;Cataldo Arcuri

  • Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

    Maria T Pallotta;Ciriana Orabona;Claudia Volpi;Carmine Vacca

  • Aryl hydrocarbon receptor control of a disease tolerance defence pathway

    Alban Bessede;Alban Bessede;Marco Gargaro;Maria T. Pallotta;Davide Matino

  • CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86

    Ciriana Orabona;Ursula Grohmann;Maria Laura Belladonna;Francesca Fallarino

  • Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy.

    Ursula Grohmann;Claudia Volpi;Francesca Fallarino;Silvia Bozza

  • IL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 Production

    Ursula Grohmann;Maria Laura Belladonna;Roberta Bianchi;Ciriana Orabona

  • IL-23 and IL-12 Have Overlapping, but Distinct, Effects on Murine Dendritic Cells

    Maria Laura Belladonna;Jean-Christophe Renauld;Roberta Bianchi;Carmine Vacca

  • A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells.

    Giada Mondanelli;Roberta Bianchi;Maria Teresa Pallotta;Ciriana Orabona

  • Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells

    Francesca Fallarino;Carmine Vacca;Ciriana Orabona;Maria L. Belladonna

  • S100B/RAGE-dependent activation of microglia via NF-kappaB and AP-1 Co-regulation of COX-2 expression by S100B, IL-1beta and TNF-alpha.

    Roberta Bianchi;Ileana Giambanco;Rosario Donato

  • Murine Plasmacytoid Dendritic Cells Initiate the Immunosuppressive Pathway of Tryptophan Catabolism in Response to CD200 Receptor Engagement

    Francesca Fallarino;Carine Asselin-Paturel;Carmine Vacca;Roberta Bianchi

  • S100B protein stimulates microglia migration via RAGE-dependent up-regulation of chemokine expression and release.

    Roberta Bianchi;Eirini Kastrisianaki;Ileana Giambanco;Rosario Donato

  • S100B Protein, a Damage-Associated Molecular Pattern Protein in the Brain and Heart, and Beyond

    Guglielmo Sorci;Roberta Bianchi;Francesca Riuzzi;Claudia Tubaro

  • A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice.

    Ursula Grohmann;Francesca Fallarino;Roberta Bianchi;Ciriana Orabona

  • The Pathophysiological Role of Microglia in Dynamic Surveillance, Phagocytosis and Structural Remodeling of the Developing CNS

    Cataldo Arcuri;Carmen Mecca;Roberta Bianchi;Ileana Giambanco

  • Toward the identification of a tolerogenic signature in IDO-competent dendritic cells.

    Ciriana Orabona;Paolo Puccetti;Paolo Puccetti;Carmine Vacca;Carmine Vacca;Silvio Bicciato;Silvio Bicciato

Frequent Co-Authors

Paolo Puccetti
Paolo Puccetti University of Perugia
Ursula Grohmann
Ursula Grohmann University of Perugia
Maria C. Fioretti
Maria C. Fioretti University of Perugia
Francesca Fallarino
Francesca Fallarino University of Perugia
Ciriana Orabona
Ciriana Orabona University of Perugia
Rosario Donato
Rosario Donato University of Perugia
Carmine Vacca
Carmine Vacca University of Perugia
Luigina Romani
Luigina Romani University of Perugia
Silvio Bicciato
Silvio Bicciato University of Modena and Reggio Emilia
Enzo Bonmassar
Enzo Bonmassar University of Rome Tor Vergata

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