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Shinya Yoshikawa

Shinya Yoshikawa

D-Index & Metrics

Chemistry

D-Index
48
Citations
13483
World Ranking
15049
National Ranking
1173

Overview

Shinya Yoshikawa is affiliated with the University of Hyogo in Japan and focuses their research on biochemistry, genetics, and molecular biology with particular emphasis on molecular biology. Their work encompasses notable subfields including cellular and molecular neuroscience, materials chemistry, surgery, and atomic and molecular physics, and optics.

Their research contributions span several key topics such as photosynthetic processes and mechanisms, photoreceptor and optogenetics research, spectroscopy and quantum chemical studies, mitochondrial function and pathology, electrochemical sensors and biosensors, protein structure and dynamics, and ATP synthase and ATPases research.

Yoshikawa has published extensively, with frequent appearances in the Journal of Biological Chemistry, contributing three papers there. Other publication venues include Frontiers in Chemistry, BBA Advances, Mitochondrion, and Biochemical Journal.

  • X-ray structures of catalytic intermediates of cytochrome c oxidase provide insights into its O2 activation and unidirectional proton-pump mechanisms, 2020, Journal of Biological Chemistry
  • Critical roles of the CuB site in efficient proton pumping as revealed by crystal structures of mammalian cytochrome c oxidase catalytic intermediates, 2021, Journal of Biological Chemistry
  • Recent progress in experimental studies on the catalytic mechanism of cytochrome c oxidase, 2023, Frontiers in Chemistry
  • The 1.3-Å resolution structure of bovine cytochrome c oxidase suggests a dimerization mechanism, 2021, BBA Advances
  • Mitochondrial respiration is controlled by Allostery, Subunit Composition and Phosphorylation Sites of Cytochrome c Oxidase: A trailblazer's tale - Bernhard Kadenbach, 2021, Mitochondrion

Frequent co-authors collaborating with Yoshikawa include Kyoko Shinzawa-Itoh, Tomitake Tsukihara, Atsuhiro Shimada, Eiki Yamashita, and Kazumasa Muramoto.

Best Publications

  • The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A.

    Tomitake Tsukihara;Hiroshi Aoyama;Eiki Yamashita;Takashi Tomizaki

  • Structures of metal sites of oxidized bovine heart cytochrome c oxidase at 2.8 A

    Tomitake Tsukihara;Hiroshi Aoyama;Eiki Yamashita;Takashi Tomizaki

  • Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase.

    Shinya Yoshikawa;Kyoko Shinzawa-Itoh;Ryosuke Nakashima;Rieko Yaono

  • Reaction Mechanism of Cytochrome c Oxidase

    Shinya Yoshikawa;Atsuhiro Shimada

  • The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process

    Tomitake Tsukihara;Kunitoshi Shimokata;Yukie Katayama;Hideo Shimada

  • Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase

    Kyoko Shinzawa-Itoh;Hiroshi Aoyama;Kazumasa Muramoto;Hirohito Terada

  • Determination of damage-free crystal structure of an X-ray-sensitive protein using an XFEL

    Kunio Hirata;Kyoko Shinzawa-Itoh;Naomine Yano;Shuhei Takemura

  • Architecture of helix bundle membrane proteins: An analysis of cytochrome c oxidase from bovine mitochondria

    Erik Wallin;T. Tsukihara;S. Yoshikawa;G. von Heijne

  • Bovine cytochrome c oxidase structures enable O2 reduction with minimization of reactive oxygens and provide a proton-pumping gate

    Kazumasa Muramoto;Kazuhiro Ohta;Kyoko Shinzawa-Itoh;Katsumasa Kanda

  • The proton pumping pathway of bovine heart cytochrome c oxidase

    Kunitoshi Shimokata;Yukie Katayama;Haruka Murayama;Makoto Suematsu

  • Selective resonance Raman observation of the "607 nm" form generated in the reaction of oxidized cytochrome c oxidase with hydrogen peroxide.

    Denis A. Proshlyakov;Takashi Ogura;Kyoko Shinzawa-Itoh;Shinya Yoshikawa

  • A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase.

    Kazumasa Muramoto;Kunio Hirata;Kyoko Shinzawa-Itoh;Shinji Yoko-o

  • A peroxide bridge between Fe and Cu ions in the O2 reduction site of fully oxidized cytochrome c oxidase could suppress the proton pump.

    Hiroshi Aoyama;Kazumasa Muramoto;Kyoko Shinzawa-Itoh;Kunio Hirata

  • ATP and ADP bind to cytochrome c oxidase and regulate its activity.

    Jörg Napiwotzki;Kyoko Shinzawa-Itoh;Shinya Yoshikawa;Bernhard Kadenbach

  • Proton-Pumping Mechanism of Cytochrome c Oxidase

    Shinya Yoshikawa;Kazumasa Muramoto;Kyoko Shinzawa-Itoh

  • Higd1a is a positive regulator of cytochrome c oxidase

    Takaharu Hayashi;Yoshihiro Asano;Yasunori Shintani;Hiroshi Aoyama

  • Time-resolved resonance Raman elucidation of the pathway for dioxygen reduction by cytochrome c oxidase

    Takashi Ogura;Satoshi Takahashi;Shun Hirota;Kyoko Shinzawa-Itoh

  • Complex structure of cytochrome c-cytochrome c oxidase reveals a novel protein-protein interaction mode

    Satoru Shimada;Kyoko Shinzawa‐Itoh;Junpei Baba;Shimpei Aoe

  • Crystal Structure of Bovine Heart Cytochrome c Oxidase at 2.8 Å Resolution

    Shinya Yoshikawa;Kyoko Shinzawa-Itoh;Tomitake Tsukihara

  • Time-Resolved Resonance Raman Evidence for Tight Coupling between Electron Transfer and Proton Pumping of Cytochrome c Oxidase upon the Change from the FeV Oxidation Level to the FeIV Oxidation Level

    Takashi Ogura;Shun Hirota;Denis A. Proshlyakov;Kyoko Shinzawa-Itoh

Frequent Co-Authors

Tomitake Tsukihara
Tomitake Tsukihara University of Hyogo
Eiki Yamashita
Eiki Yamashita Osaka University
Takashi Ogura
Takashi Ogura University of Hyogo
Teizo Kitagawa
Teizo Kitagawa University of Hyogo
Makoto Suematsu
Makoto Suematsu Keio University
Masaki Yamamoto
Masaki Yamamoto University of Hyogo
Min Yao
Min Yao Hokkaido University
Shun Hirota
Shun Hirota Nara Institute of Science and Technology
Satoshi Takahashi
Satoshi Takahashi Tohoku University
Yoshinori Fujiyoshi
Yoshinori Fujiyoshi Nagoya University

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