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Biology and Biochemistry

D-Index
57
Citations
12712
World Ranking
13752
National Ranking
5824

Overview

Maik Hüttemann is affiliated with Wayne State University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their scientific work spans various specialized subfields such as molecular biology, hematology, physiology, cancer research, and radiology, nuclear medicine, and imaging.

The researcher's publication record includes significant contributions on topics related to mitochondrial function and pathology, acute myeloid leukemia research, ATP synthase and ATPases, histone deacetylase inhibitors, cancer, hypoxia, metabolism, protein degradation and inhibitors, as well as photoreceptor and optogenetics research.

Frequent publication venues for their work include:

  • Cells
  • Biochemical Pharmacology
  • Biomolecules
  • Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • Proceedings of the National Academy of Sciences

Co-authors who have collaborated with Maik Hüttemann often include:

  • Paul T. Morse
  • Junmei Wan
  • Tasnim Arroum
  • Hasini A. Kalpage
  • Jeffrey W. Taub

Selected recent papers authored or co-authored by Maik Hüttemann demonstrate engagement with cellular mechanisms and disease pathology:

  • "Targeting multiple signaling pathways: the new approach to acute myeloid leukemia therapy" (2020), published in Signal Transduction and Targeted Therapy
  • "Cytochrome c phosphorylation: Control of mitochondrial electron transport chain flux and apoptosis" (2020), published in The International Journal of Biochemistry & Cell Biology
  • "Diverse functions of cytochrome c in cell death and disease" (2024), published in Cell Death and Differentiation
  • "Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors" (2020), published in Science Signaling
  • "Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis" (2022), published in Proceedings of the National Academy of Sciences

Best Publications

  • Molecular Mechanisms of Ischemia–Reperfusion Injury in Brain: Pivotal Role of the Mitochondrial Membrane Potential in Reactive Oxygen Species Generation

    Thomas H. Sanderson;Christian A. Reynolds;Rita Kumar;Karin Przyklenk

  • The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis.

    Maik Hüttemann;Petr Pecina;Matthew Rainbolt;Thomas H. Sanderson

  • Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model

    Ze Zheng;Xiaohua Xu;Xuebao Zhang;Aixia Wang

  • Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase.

    Bernhard Kadenbach;Maik Hüttemann;Susanne Arnold;Icksoo Lee

  • Regulation of mitochondrial respiration and apoptosis through cell signaling: Cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation

    Maik Hüttemann;Stefan Helling;Thomas H. Sanderson;Christopher Sinkler

  • Cytochrome C oxidase and the regulation of oxidative phosphorylation.

    Bernd Ludwig;Elisabeth Bender;Susanne Arnold;Maik Hüttemann

  • Regulation of mitochondrial oxidative phosphorylation through cell signaling.

    Maik Hüttemann;Icksoo Lee;Lobelia Samavati;Hong Yu

  • The possible role of cytochrome c oxidase in stress-induced apoptosis and degenerative diseases

    Bernhard Kadenbach;Susanne Arnold;Icksoo Lee;Maik Hüttemann

  • Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease.

    Maik Hüttemann;Icksoo Lee;Alena Pecinova;Petr Pecina

  • STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria.

    Lobelia Samavati;Ruchi Rastogi;Ruchi Rastogi;Wenjin Du;Wenjin Du;Maik Hüttemann

  • Molecular Mechanisms and Therapeutic Effects of (−)-Epicatechin and Other Polyphenols in Cancer, Inflammation, Diabetes, and Neurodegeneration

    Joseph Shay;Hosam A. Elbaz;Icksoo Lee;Steven P. Zielske

  • cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity.

    Icksoo Lee;Arthur R. Salomon;Scott Ficarro;Isabella Mathes

  • Metformin, the Aspirin of the 21st Century: Its Role in Gestational Diabetes Mellitus, Prevention of Preeclampsia and Cancer, and the Promotion of Longevity

    Roberto Romero;Offer Erez;Offer Erez;Offer Erez;Maik Hüttemann;Eli Maymon;Eli Maymon;Eli Maymon

  • Mammalian subunit IV isoforms of cytochrome c oxidase.

    Maik Hüttemann;Bernhard Kadenbach;Lawrence I. Grossman

  • Epidermal Growth Factor Receptor Translocation to the Mitochondria: REGULATION AND EFFECT

    Michelle L. Demory;Julie L. Boerner;Julie L. Boerner;Robert Davidson;William Faust

  • The subunit composition and function of mammalian cytochrome c oxidase

    Bernhard Kadenbach;Maik Hüttemann

  • TXNIP Links Innate Host Defense Mechanisms to Oxidative Stress and Inflammation in Retinal Muller Glia under Chronic Hyperglycemia: Implications for Diabetic Retinopathy

    Takhellambam S. Devi;Icksoo Lee;Maik Hüttemann;Ashok Kumar

  • Cardiolipin and mitochondrial phosphatidylethanolamine have overlapping functions in mitochondrial fusion in Saccharomyces cerevisiae.

    Amit S. Joshi;Morgan N. Thompson;Naomi Fei;Maik Hüttemann

  • Tumor necrosis factor alpha inhibits oxidative phosphorylation through tyrosine phosphorylation at subunit I of cytochrome c oxidase

    Lobelia Samavati;Icksoo Lee;Isabella Mathes;Friedrich Lottspeich

  • MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.

    Siddhesh Aras;Minbo Bai;Icksoo Lee;Roger Springett

Frequent Co-Authors

Lawrence I. Grossman
Lawrence I. Grossman Wayne State University
Bernhard Kadenbach
Bernhard Kadenbach Philipp University of Marburg
Miriam L. Greenberg
Miriam L. Greenberg Wayne State University
John Kamholz
John Kamholz University of Iowa Hospitals and Clinics
Valerian E. Kagan
Valerian E. Kagan University of Pittsburgh
Norbert Weissmann
Norbert Weissmann University of Giessen
Offer Erez
Offer Erez Soroka Medical Center
Jeffrey W. Taub
Jeffrey W. Taub Wayne State University
Derek E. Wildman
Derek E. Wildman University of South Florida
Carlos T. Moraes
Carlos T. Moraes University of Miami

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