World's Best Scientists 2026 revealed!
Lawrence I. Grossman

Lawrence I. Grossman

D-Index & Metrics

Molecular Biology

D-Index
71
Citations
16019
World Ranking
1383
National Ranking
703

Overview

Lawrence I. Grossman is affiliated with Wayne State University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions also in Medicine.

The scientist's work encompasses several subfields, including Molecular Biology, Epidemiology, Cancer Research, Pulmonary and Respiratory Medicine, and Physiology. Their research topics focus on mitochondrial function and pathology, ATP synthase and ATPases research, preterm birth and chorioamnionitis, cancer, hypoxia, and metabolism, neonatal respiratory health research, birth, development, and health, as well as pregnancy and preeclampsia studies.

Recent publications from Lawrence I. Grossman demonstrate a concentration on mitochondrial biology and cellular mechanisms relevant to health and disease. Notable papers include:

  • "Cytochrome c phosphorylation: Control of mitochondrial electron transport chain flux and apoptosis," 2020, The International Journal of Biochemistry & Cell Biology
  • "Acute O 2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors," 2020, Science Signaling
  • "Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms," 2020, Proceedings of the National Academy of Sciences
  • "Fetal and maternal NLRP3 signaling is required for preterm labor and birth," 2022, JCI Insight
  • "Regulation of mitochondrial oxidative phosphorylation through tight control of cytochrome c oxidase in health and disease - Implications for ischemia/reperfusion injury, inflammatory diseases, diabetes, and cancer," 2024, Redox Biology

Frequent collaborators in their research include Siddhesh Aras, Neeraja Purandare, Maik Hüttemann, Roberto Romero, and Nardhy Gomez-Lopez.

Lawrence I. Grossman publishes often in journals and venues such as Biochimica et Biophysica Acta (BBA) - Bioenergetics, bioRxiv (Cold Spring Harbor Laboratory), The Journal of Maternal-Fetal & Neonatal Medicine, Proceedings of the National Academy of Sciences, and Cells.

Best Publications

  • Brain ischemia and reperfusion: Molecular mechanisms of neuronal injury

    Blaine C White;Jonathon M Sullivan;Donald J DeGracia;Brian J O’Neil

  • Metabolic costs and evolutionary implications of human brain development

    Christopher W. Kuzawa;Harry T. Chugani;Lawrence I. Grossman;Leonard Lipovich

  • The petite mutation in yeast. Loss of mitochondrial deoxyribonucleic acid during induction of petites with ethidium bromide.

    Elizabeth S. Goldring;Lawrence I. Grossman;Deborah Krupnick;Dennis R. Cryer

  • Evolution of increased glia-neuron ratios in the human frontal cortex.

    Chet C. Sherwood;Cheryl D. Stimpson;Mary Ann Raghanti;Derek E. Wildman

  • Implications of natural selection in shaping 99.4% nonsynonymous DNA identity between humans and chimpanzees: Enlarging genus Homo

    Derek E. Wildman;Monica Uddin;Guozhen Liu;Lawrence I. Grossman

  • Electrophoresis of DNA in agarose gels. Optimizing separations of conformational isomers of double- and single-stranded DNAs

    Paul H. Johnson;Lawrence I. Grossman

  • Evolution of the mammalian placenta revealed by phylogenetic analysis

    Derek E. Wildman;Caoyi Chen;Offer Erez;Offer Erez;Lawrence I. Grossman

  • Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model

    Ze Zheng;Xiaohua Xu;Xuebao Zhang;Aixia Wang

  • Regulation of mitochondrial respiration and apoptosis through cell signaling: Cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation

    Maik Hüttemann;Stefan Helling;Thomas H. Sanderson;Christopher Sinkler

  • Sister grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profiles

    Monica Uddin;Derek E. Wildman;Guozhen Liu;Wenbo Xu

  • cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity.

    Icksoo Lee;Arthur R. Salomon;Scott Ficarro;Isabella Mathes

  • Mammalian subunit IV isoforms of cytochrome c oxidase.

    Maik Hüttemann;Bernhard Kadenbach;Lawrence I. Grossman

  • A primate subfamily of galectins expressed at the maternal–fetal interface that promote immune cell death

    Nandor Gabor Than;Roberto Romero;Morris Goodman;Amy Weckle

  • Accelerated evolution of the electron transport chain in anthropoid primates.

    Lawrence I. Grossman;Derek E. Wildman;Timothy R. Schmidt;Morris Goodman

  • Mitochondrial DNA in Yeast and Some Mammalian Species

    Gianmarco Corneo;Cyril Moore;D. Rao Sanadi;Lawrence I. Grossman

  • Location and structure of the var1 gene on yeast mitochondrial DNA: nucleotide sequence of the 40.0 allele.

    Michael E.S. Hudspeth;W.Michael Ainley;Deborah S. Shumard;Ronald A. Butow

  • The reaction of formaldehyde with nucleotides and T2 bacteriophage DNA.

    Lawrence Grossman;Stephen S. Levine;William S. Allison

  • Brain injury by global ischemia and reperfusion: A theoretical perspective on membrane damage and repair

    Blaine C. White;Lawrence I. Grossman;Gary S. Krause

  • Starch-gel electrophoresis of malate dehydrogenase.

    C.J.R. Thorne;L.I. Grossman;N.O. Kaplan

  • Proapoptotic BAX and BAK Modulate the Unfolded Protein Response by a Direct Interaction with IRE1a

    L. I. Grossman;D. E. Wildman;T. R. Schmidt;M. Goodman

Frequent Co-Authors

Maik Hüttemann
Maik Hüttemann Wayne State University
Derek E. Wildman
Derek E. Wildman University of South Florida
Morris Goodman
Morris Goodman Wayne State University
Chet C. Sherwood
Chet C. Sherwood George Washington University
Roberto Romero
Roberto Romero National Institutes of Health
Patrick R. Hof
Patrick R. Hof Icahn School of Medicine at Mount Sinai
Offer Erez
Offer Erez Soroka Medical Center
Leonard Lipovich
Leonard Lipovich Wayne State University
John Kamholz
John Kamholz University of Iowa Hospitals and Clinics
Norbert Weissmann
Norbert Weissmann University of Giessen

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Molecular Biology in the USA opens doors to a wide range of interdisciplinary careers and further study opportunities. As the demand for specialized and flexible education grows, many students are considering online degree programs to complement or expand their science background.

For those interested in supporting communities or individuals, a human services bachelors degree online can provide a strong foundation in people-centered roles, complementing scientific expertise. Another compelling route involves communication sciences; professionals seeking a new direction may pursue a transition from educator to clinician by exploring how to move from teacher to speech and language therapist, often through specialized online programs.

Molecular Biology majors with an interest in structural and spatial design can consider integrating their knowledge with an architecture online degree, opening pathways in bioengineering and biotechnology facilities. Additionally, strong analytical and quantitative skills are essential in today’s scientific landscape—earning a bachelor in mathematics online can help you stand out for both research and industry roles.

Best Scientists Citing Lawrence I. Grossman

Trending Scientists

Recently Published Articles