World's Best Scientists 2026 revealed!

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Chemistry

D-Index
42
Citations
8481
World Ranking
17407
National Ranking
2617

Overview

Yu Zhou is affiliated with the Chinese Academy of Sciences in China and has contributed extensively to the field of Chemistry, with particular emphasis on Organic Chemistry. Their research portfolio spans 185 publications, featuring a strong focus on Organic Chemistry, alongside work in Molecular Biology, Oncology, Inorganic Chemistry, and Pharmacology.

The scientist's main topics of research encompass several specialized areas, including:

  • Catalytic C-H Functionalization Methods
  • Synthesis and Catalytic Reactions
  • Sulfur-Based Synthesis Techniques
  • Cyclopropane Reaction Mechanisms
  • Radical Photochemical Reactions
  • Asymmetric Hydrogenation and Catalysis
  • Catalytic Cross-Coupling Reactions

Yu Zhou's publication record features papers in notable scientific journals, among which the following are highlighted:

  • "Pembrolizumab Versus Placebo as Second-Line Therapy in Patients From Asia With Advanced Hepatocellular Carcinoma: A Randomized, Double-Blind, Phase III Trial," 2022, Journal of Clinical Oncology
  • "Structures of Gi-bound metabotropic glutamate receptors mGlu2 and mGlu4," 2021, Nature
  • "Structures of human mGlu2 and mGlu7 homo- and heterodimers," 2021, Nature
  • "Lateral septum-lateral hypothalamus circuit dysfunction in comorbid pain and anxiety," 2023, Molecular Psychiatry
  • "Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate," 2021, Journal of Medicinal Chemistry

Frequent co-authors collaborating with Yu Zhou include:

  • Hong Liu (43 joint publications)
  • Chunpu Li (11 joint publications)
  • Jianhui Zhou (11 joint publications)
  • Xuewu Liang (8 joint publications)
  • Gen Luo (8 joint publications)

Yu Zhou often publishes in journals with a strong focus on organic and medicinal chemistry, including:

  • Organic Letters (11 publications)
  • The Journal of Organic Chemistry (9 publications)
  • Journal of Medicinal Chemistry (8 publications)
  • Organic Chemistry Frontiers (7 publications)
  • Green Chemistry (4 publications)

This profile illustrates a research career concentrated primarily in chemistry, with integrated contributions to molecular biology and oncology, reflecting interdisciplinary approaches toward synthesis, catalytic methodologies, and biologically relevant molecular structures.

Best Publications

  • Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

    Yu Zhou;Jiang Wang;Zhanni Gu;Shuni Wang

  • Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

    Jing Wang;Cheng Luo;Changliang Shan;Qiancheng You;Qiancheng You

  • Recent advances in the gold-catalyzed additions to C–C multiple bonds

    He Huang;Yu Zhou;Hong Liu

  • Ruthenium-Catalyzed Redox-Neutral [4 + 1] Annulation of Benzamides and Propargyl Alcohols via C–H Bond Activation

    Xiaowei Wu;Bao Wang;Bao Wang;Shengbin Zhou;Yu Zhou

  • Structures of Gi-bound metabotropic glutamate receptors mGlu2 and mGlu4

    Shuling Lin;Shuo Han;Xiaoqing Cai;Qiuxiang Tan

  • Propargyl Alcohols as One-Carbon Synthons: Redox-Neutral Rhodium(III)-Catalyzed C–H Bond Activation for the Synthesis of Isoindolinones Bearing a Quaternary Carbon

    Xiaowei Wu;Bao Wang;Bao Wang;Yu Zhou;Hong Liu

  • Structures of human mGlu2 and mGlu7 homo- and heterodimers

    Juan Du;Dejian Wang;Hongcheng Fan;Chanjuan Xu

  • Rhodium(III)-Catalyzed C-H Activation of Benzoylacetonitriles and Cyclization with Sulfoxonium Ylides to Naphthols

    Chaofan Zhou;Chaofan Zhou;Feifei Fang;Yilang Cheng;Yazhou Li

  • Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D1, D2 and serotonin 5-HT1A multi-action profile

    Haifeng Sun;Liyuan Zhu;Huicui Yang;Wangke Qian

  • Ruthenium(II)-catalyzed selective C–H bond activation of imidamides and coupling with sulfoxonium ylides: an efficient approach for the synthesis of highly functional 3-ketoindoles

    Chenglin Wu;Chenglin Wu;Jianhui Zhou;Guoxue He;Huihui Li

  • Gold-catalyzed intramolecular hydroamination of terminal alkynes in aqueous media: efficient and regioselective synthesis of indole-1-carboxamides

    Deju Ye;Jinfang Wang;Xu Zhang;Xu Zhang;Yu Zhou

  • Ligand-free iron/copper cocatalyzed N-arylations of aryl halides with amines under microwave irradiation

    Diliang Guo;Diliang Guo;He Huang;Yu Zhou;Jinyi Xu

  • An expedient Pd/DBU mediated cyanation of aryl/heteroaryl bromides with K4[Fe(CN)6]

    Dengyou Zhang;Haifeng Sun;Lei Zhang;Yu Zhou

  • Regioselective synthesis of 3-benzazepinones and unexpected 5-bromo-3-benzazepinones.

    Lei Zhang;Deju Ye;Yu Zhou;Guannan Liu

  • Catalytic and catalyst-free diboration of alkynes

    Fei Zhao;Xiuwen Jia;Pinyi Li;Jingwei Zhao

  • A Mannich/cyclization cascade process for the asymmetric synthesis of spirocyclic thioimidazolidineoxindoles

    Hao Cai;Hao Cai;Yu Zhou;Dong Zhang;Dong Zhang;Jinyi Xu

  • Gold-Catalyzed One-Pot Cascade Construction of Highly Functionalized Pyrrolo[1,2-a]quinolin-1(2H)-ones

    Yu Zhou;Enguang Feng;Guannan Liu;Deju Ye

  • Metal-free tandem reaction in water: An efficient and regioselective synthesis of 3-hydroxyisoindolin-1-ones

    Yu Zhou;Yun Zhai;Jian Li;Deju Ye

  • Gold(I)‐Catalyzed One‐Pot Tandem Coupling/Cyclization: An Efficient Synthesis of Pyrrolo‐/Pyrido[2,1‐b]benzo[d][1,3]oxazin‐ 1‐ones

    Yu Zhou;Yun Zhai;Xun Ji;Xun Ji;Guannan Liu

  • Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist.

    Wanchao Yin;X. Edward Zhou;X. Edward Zhou;Dehua Yang;Parker W. de Waal

  • Rh(III)-Catalyzed C-H Activation of Benzoylacetonitriles and Tandem Cyclization with Diazo Compounds to Substituted Benzo[ de]chromenes.

    Feifei Fang;Feifei Fang;Chunmei Zhang;Chaofan Zhou;Yazhou Li

  • Metal-Free Synthesis of 2-Substituted (N, O, C) Benzothiazoles via an Intramolecular C-S Bond Formation

    Enguang Feng;He Huang;Yu Zhou;Deju Ye

  • Gold(I)-Catalyzed Tandem Transformation: A Simple Approach for the Synthesis of Pyrrolo/Pyrido[2,1-a][1,3]benzoxazinones and Pyrrolo/Pyrido[2,1-a]quinazolinones

    Enguang Feng;Yu Zhou;Dengyou Zhang;Lei Zhang

Frequent Co-Authors

Hong Liu
Hong Liu Shandong University
Hualiang Jiang
Hualiang Jiang Chinese Academy of Sciences
Deju Ye
Deju Ye Nanjing University
Kaixian Chen
Kaixian Chen Chinese Academy of Sciences
Jinyi Xu
Jinyi Xu China Pharmaceutical University
Jian Li
Jian Li ShanghaiTech University
Xiaomin Luo
Xiaomin Luo Chinese Academy of Sciences
Cheng Luo
Cheng Luo Chinese Academy of Sciences
Xuechu Zhen
Xuechu Zhen Soochow University
Hui Wang
Hui Wang Chinese Academy of Sciences

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