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Chemistry

D-Index
84
Citations
25752
World Ranking
2816
National Ranking
160

Overview

Norio Shibata is affiliated with the Nagoya Institute of Technology in Japan. Their research primarily focuses on the field of Chemistry, with a significant output in Organic Chemistry, Materials Chemistry, and Pharmaceutical Science. Additional subfields of study include Molecular Biology and Inorganic Chemistry.

The scientist's main research topics cover areas related to fluorine chemistry and crystallography. These topics include:

  • Fluorine in Organic Chemistry
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Inorganic Fluorides and Related Compounds
  • Catalytic C-H Functionalization Methods
  • Chemical Synthesis and Analysis
  • Sulfur-Based Synthesis Techniques

Shibata has published extensively in various scientific venues. Frequent publication venues include:

  • The Cambridge Structural Database
  • Organic Letters
  • The Journal of Organic Chemistry
  • Nature Communications
  • Chemical Science

Their recent papers demonstrate involvement in organic fluorine chemistry and related pharmaceutical and agrochemical applications. Notable recent publications include:

  • "Contribution of Organofluorine Compounds to Pharmaceuticals" (2020), ACS Omega
  • "Current Contributions of Organofluorine Compounds to the Agrochemical Industry" (2020), iScience
  • "Structural bases of IMiD selectivity that emerges by 5-hydroxythalidomide" (2020), Nature Communications
  • "A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues" (2022), Nature Communications
  • "Thalidomide and its metabolite 5-hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF" (2021), The EMBO Journal

Shibata frequently collaborates with other researchers. Among frequent co-authors are Hiroto Uno, Yuji Sumii, Koki Kawai, Zhengyu Zhao, and Motoo Shiro.

Best Publications

  • Contribution of Organofluorine Compounds to Pharmaceuticals.

    Munenori Inoue;Yuji Sumii;Norio Shibata;Norio Shibata

  • Current Contributions of Organofluorine Compounds to the Agrochemical Industry.

    Yuta Ogawa;Etsuko Tokunaga;Osamu Kobayashi;Kenji Hirai

  • Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions

    Xiu-Hua Xu;Kohei Matsuzaki;Norio Shibata

  • Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

    Yi Zhu;Jianlin Han;Jiandong Wang;Norio Shibata

  • Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.

    Peter L. Roach;Ian J. Clifton;Charles M. H. Hensgens;Norio Shibata

  • Recent advances in enantioselective trifluoromethylation reactions

    Norio Shibata;Satoshi Mizuta;Hiroyuki Kawai

  • Cinchona Alkaloid Catalyzed Enantioselective Fluorination of Allyl Silanes, Silyl Enol Ethers, and Oxindoles

    Takehisa Ishimaru;Norio Shibata;Takao Horikawa;Naomi Yasuda

  • Highly Enantioselective Catalytic Fluorination and Chlorination Reactions of Carbonyl Compounds Capable of Two‐Point Binding

    Norio Shibata;Junji Kohno;Kazumi Takai;Takehisa Ishimaru

  • Trifluoromethanesulfonyl hypervalent iodonium ylide for copper-catalyzed trifluoromethylthiolation of enamines, indoles, and β-keto esters.

    Yu-Dong Yang;Ayaka Azuma;Etsuko Tokunaga;Mikio Yamasaki

  • Recent Advances in Enantioselective Trifluoromethylation Reactions

    Norio Shibata;Satoshi Mizuta;Takeshi Toru

  • Lewis Acid-Catalyzed Enantioselective Hydroxylation Reactions of Oxindoles and β-Keto Esters Using DBFOX Ligand

    Takehisa Ishimaru;Norio Shibata;Jun Nagai;Shuichi Nakamura

  • Shelf-stable electrophilic trifluoromethylating reagents: A brief historical perspective

    Norio Shibata;Andrej Matsnev;Dominique Cahard

  • Enantioselective Fluorination Mediated by Cinchona Alkaloid Derivatives/Selectfluor Combinations: Reaction Scope and Structural Information for N-Fluorocinchona Alkaloids

    Norio Shibata;Emiko Suzuki;Toru Asahi;Motoo Shiro

  • A Fundamentally New Approach to Enantioselective Fluorination Based on Cinchona Alkaloid Derivatives/Selectfluor Combination

    Norio Shibata;and Emiko Suzuki;Yoshio Takeuchi

  • Fluorinated Johnson Reagent for Transfer-Trifluoromethylation to Carbon Nucleophiles

    Shun Noritake;Norio Shibata;Shuichi Nakamura;Takeshi Toru

  • Iodoarene-catalyzed fluorination and aminofluorination by an Ar-I/HF·pyridine/mCPBA system

    Satoru Suzuki;Tomohiro Kamo;Kazunobu Fukushi;Takaaki Hiramatsu

  • Enantioselective Synthesis of AG‐041R by using N‐Heteroarenesulfonyl Cinchona Alkaloid Amides as Organocatalysts

    Noriyuki Hara;Shuichi Nakamura;Masahide Sano;Ryota Tamura

  • Cinchona-alkaloid-catalyzed enantioselective direct aldol-type reaction of oxindoles with ethyl trifluoropyruvate.

    Shinichi Ogawa;Norio Shibata;Junji Inagaki;Shuichi Nakamura

  • Fluorobis(phenylsulfonyl)methane: a fluoromethide equivalent and palladium-catalyzed enantioselective allylic monofluoromethylation.

    Takeo Fukuzumi;Norio Shibata;Masayoshi Sugiura;Hiroyuki Yasui

  • Catalytic Enantioselective Trifluoromethylation of Azomethine Imines with Trimethyl(trifluoromethyl)silane

    Hiroyuki Kawai;Akihiro Kusuda;Shuichi Nakamura;Motoo Shiro

Frequent Co-Authors

Shuichi Nakamura
Shuichi Nakamura Nagoya Institute of Technology
Motoo Shiro
Motoo Shiro Nagoya Institute of Technology
Yasuyuki Kita
Yasuyuki Kita Ritsumeikan University
Dominique Cahard
Dominique Cahard Centre national de la recherche scientifique, CNRS
F. Peter Guengerich
F. Peter Guengerich Vanderbilt University
Hiroshi Yamazaki
Hiroshi Yamazaki Showa Pharmaceutical University
Hiroyasu Sato
Hiroyasu Sato Mie University
Seiji Tsuzuki
Seiji Tsuzuki University of Tokyo
Kenneth L. Kirk
Kenneth L. Kirk National Institutes of Health
Jack E. Baldwin
Jack E. Baldwin University of Oxford

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