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Chemistry
Japan
2026

D-Index & Metrics

Chemistry

D-Index
95
Citations
35651
World Ranking
1608
National Ranking
75

Research.com Recognitions

  • 2026 - Research.com Chemistry in Japan Leader Award
  • 2025 - Research.com Chemistry in Japan Leader Award
  • 2022 - Research.com Chemistry in Japan Leader Award

Overview

Hiroshi Yamazaki is affiliated with Showa Pharmaceutical University in Japan. Their research spans multiple fields, primarily focusing on engineering and medicine. Their work integrates various subfields including inorganic chemistry, mechanical engineering, catalysis, biomedical engineering, and toxicology.

Their research covers several specific topics, prominently focusing on zeolite catalysis and synthesis, catalysis and hydrodesulfurization studies, catalysis and oxidation reactions, catalysis for biomass conversion, pharmacovigilance and adverse drug reactions, drug-induced adverse reactions, and electroconvulsive therapy studies.

Yamazaki has published in a diverse set of academic journals. Frequent publication venues include:

  • Applied Catalysis A General
  • Catalysis Communications
  • In Vivo
  • The Journal Of Hand Surgery
  • Frontiers in Pharmacology

Their recent notable papers are:

  • Al ion-exchanged USY in FCC catalyst for high LPG yield, 2021, Catalysis Communications
  • Effects of the FCC catalyst binder type on propylene production during catalytic cracking of VGO, 2023, Applied Catalysis A General
  • Time-to-onset Analysis of Rhabdomyolysis due to Different Proton Pump Inhibitors Using a Pharmacovigilance Database, 2024, In Vivo
  • Regulatory-required post-marketing database studies in Japan could be leveraged to assess important potential risks as well as identified risks, 2025, Frontiers in Pharmacology
  • Table of Contents, 2020, The Journal Of Hand Surgery

Yamazaki collaborates frequently with colleagues including Takaki Mizuno, Yusuke Takamiya, Hiroki Hasegawa, Chisuzu Tanaka, and Tomohiro Mitsui. Each of these collaborators has worked with Yamazaki on multiple occasions, suggesting ongoing research partnerships.

Best Publications

  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

    T Shimada;H Yamazaki;M Mimura;Y Inui

  • Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1

    Tsutomu Shimada;Carrie L. Hayes;Hiroshi Yamazaki;Shantu Amin

  • Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

    H. Yamazaki;Y. Inui;Chul-Ho Yun;F. P. Guengerich

  • Activation and detoxication of aflatoxin B1

    Guengerich Fp;Johnson Ww;Shimada T;Ueng Yf

  • Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.

    Hiroshi Yamazaki;Tsutomu Shimada

  • Regio- and stereocontrolled dimerization of tert-butylacetylene to (Z)-1,4-di-tert-butylbutatriene by ruthenium catalysis. Reaction mechanism involving alkynyl-vinylidene coupling and rearrangement of the metal-bound C4 unit

    Yasuo Wakatsuki;Hiroshi Yamazaki;Nami Kumegawa;Toshiaki Satoh

  • Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population

    Genta Sawada;Genta Sawada;Atsushi Niida;Ryutaro Uchi;Hidenari Hirata

  • Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.

    T. Shimada;H. Yamazaki;M. Mimura;N. Wakamiya

  • Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens.

    T. Shimada;Chul-Ho Yun;H. Yamazaki;J.-C. Gautier

  • Oxidation of aflatoxin B1 by bacterial recombinant human cytochrome P450 enzymes.

    Yune-Fang Ueng;T. Shimada;H. Yamazaki;F. P. Guengerich

  • Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli.

    Hiroshi Yamazaki;Mami Nakamura;Tomoko Komatsu;Katsuhiro Ohyama

  • Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes.

    Hiroshi Yamazaki;Kiyoshi Inoue;Masafumi Hashimoto;Tsutomu Shimada

  • Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1.

    Shimada T;Yamazaki H;Foroozesh M;Hopkins Ne

  • Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.

    Hiroshi Yamazaki;William W. Johnson;Yune-Fang Ueng;Tsutomu Shimada

  • Heterogeneous Ni Catalyst for Direct Synthesis of Primary Amines from Alcohols and Ammonia

    Ken-ichi Shimizu;Kenichi Kon;Wataru Onodera;Hiroshi Yamazaki

  • Inhibitory effects of amiodarone and its N‐deethylated metabolite on human cytochrome P450 activities: Prediction of in vivo drug interactions

    K. Ohyama;M. Nakajima;M. Suzuki;N. Shimada

  • Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers

    Masaki Fujieda;Hiroshi Yamazaki;Tetsuya Saito;Kazuma Kiyotani

  • Roles of Cytochromes P450 1A2 and 3A4 in the Oxidation of Estradiol and Estrone in Human Liver Microsomes

    H Yamazaki;P M Shaw;F P Guengerich;T Shimada

  • High-risk and multiple human papillomavirus infections associated with cervical abnormalities in Japanese women.

    Toshiyuki Sasagawa;Walid Basha;Hiroshi Yamazaki;Masaki Inoue

  • Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans

    Tsutomu Shimada;Mayumi Mimura;Kiyoshi Inoue;Sei-ichi Nakamura

  • Acetylene .pi.-Coordination, Slippage to .sigma.-Coordination, and 1,2-Hydrogen Migration Taking Place on a Transition Metal. The case of a Ru(II) Complex as Studied by Experiment and ab Initio Molecular Orbital Simulations

    Yasuo Wakatsuki;Nobuaki Koga;Hiroshi Yamazaki;Keiji Morokuma

Frequent Co-Authors

Tsutomu Shimada
Tsutomu Shimada Osaka Metropolitan University
F. Peter Guengerich
F. Peter Guengerich Vanderbilt University
Yasuo Wakatsuki
Yasuo Wakatsuki Bridgestone (Japan)
Tetsuya Kamataki
Tetsuya Kamataki Hokkaido University
Miki Nakajima
Miki Nakajima Kanazawa University
Tsuyoshi Yokoi
Tsuyoshi Yokoi Nagoya University
Hiroyuki Kato
Hiroyuki Kato Massachusetts General Hospital
Norio Shibata
Norio Shibata Nagoya Institute of Technology
Junko N. Kondo
Junko N. Kondo Tokyo Institute of Technology
Yoshihiko Funae
Yoshihiko Funae Osaka Metropolitan University

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