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Magnus Ingelman-Sundberg

Magnus Ingelman-Sundberg

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Biology and Biochemistry
Sweden
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
134
Citations
60561
World Ranking
363
National Ranking
7

Medicine

D-Index
133
Citations
60323
World Ranking
2247
National Ranking
40

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2025 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2022 - Research.com Biology and Biochemistry in Sweden Leader Award

Overview

Magnus Ingelman-Sundberg is affiliated with the Karolinska Institute in Sweden. Their research spans several interconnected fields, focusing primarily on medicine and pharmacology, toxicology, and pharmaceutics. Over their career, they have contributed extensively to pharmacogenetics and drug metabolism, schizophrenia research and treatment, and the treatment of major depression, alongside topics related to liver disease diagnosis and treatment as well as liver physiology and pathology.

Their published work includes research on molecular biology, psychiatry and mental health, epidemiology, and oncology, reflecting a multi-disciplinary approach in biomedical sciences. More specifically, their subfields of study are pharmacology, psychiatry and mental health, molecular biology, epidemiology, and oncology.

Magnus Ingelman-Sundberg's frequent co-authors include Marin M. Jukić, Espen Molden, F. Milosavljević, Inger Johansson, and Čedo Miljević. These collaborations have contributed to consolidating their research output and presence in their primary areas of expertise.

The scientist has published multiple articles in well-regarded venues. Their frequent publication outlets include Clinical Pharmacology & Therapeutics, Neuroscience Applied, European Neuropsychopharmacology, Cells, and Trends in Pharmacological Sciences.

Recent papers authored or co-authored by Magnus Ingelman-Sundberg demonstrate a focus on pharmacogenetics and clinical applications. Notable papers include:

  • A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study (2023, The Lancet)
  • CYP2E1 in Alcoholic and Non-Alcoholic Liver Injury. Roles of ROS, Reactive Intermediates and Lipid Overload (2021, International Journal of Molecular Sciences)
  • Association of CYP2C19 and CYP2D6 Poor and Intermediate Metabolizer Status With Antidepressant and Antipsychotic Exposure (2020, JAMA Psychiatry)
  • Pharmacogenomics of Antidepressant and Antipsychotic Treatment: How Far Have We Got and Where Are We Going? (2020, Frontiers in Psychiatry)
  • Pharmacogenetics in Psychiatry: An Update on Clinical Usability (2020, Frontiers in Pharmacology)

Best Publications

  • Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects

    Magnus Ingelman-Sundberg;Sarah C. Sim;Alvin Gomez;Cristina Rodriguez-Antona

  • Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity

    M Ingelman-Sundberg

  • Dietary long-chain n−3 fatty acids for the prevention of cancer: a review of potential mechanisms

    Susanna C Larsson;Maria Kumlin;Magnus Ingelman-Sundberg;Alicja Wolk

  • Metabolic gene polymorphism frequencies in control populations.

    S. Garte;L. Gaspari;A.K. Alexandrie;C. Ambrosone

  • A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants.

    Sarah C. Sim;Sarah C. Sim;Carl Risinger;Carl Risinger;Marja‐Liisa Dahl;Marja‐Liisa Dahl;Eleni Aklillu;Eleni Aklillu

  • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine

    Inger Johansson;Eva Lundqvist;Leif Bertilsson;Marja-Liisa Dahl

  • Pharmacogenomics and Individualized Drug Therapy

    Michel Eichelbaum;Magnus Ingelman-Sundberg;William E. Evans

  • Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future

    Magnus Ingelman-Sundberg

  • Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatment.

    Magnus Ingelman-Sundberg;Mikael Oscarson;Roman A McLellan

  • Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

    Martin D. Weltman;Geoffrey C. Farrell;Pauline Hall;Magnus Ingelman‐Sundberg

  • Cytochrome P450 pharmacogenetics and cancer.

    C Rodriguez-Antona;M Ingelman-Sundberg

  • Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1).

    Gunilla Ekström;Magnus Ingelman-Sundberg

  • Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

    Catherine C. Bell;Delilah F. G. Hendriks;Sabrina M. L. Moro;Ewa Ellis

  • Nomenclature for human CYP2D6 alleles.

    A K Daly;J Brockmoller;F Broly;M Eichelbaum

  • Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.

    I. Johansson;M. Oscarson;Qun-Ying Yue;L. Bertilsson

  • Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects.

    Yitian Zhou;Magnus Ingelman‐Sundberg;Volker M. Lauschke

  • Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles.

    E Aklillu;I Persson;L Bertilsson;I Johansson

  • Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms

    Magnus Ingelman-Sundberg

  • Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis.

    M L Dahl;I Johansson;L Bertilsson;M Ingelman-Sundberg

  • Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies.

    Johansson I;Ekström G;Scholte B;Puzycki D

Frequent Co-Authors

Inger Johansson
Inger Johansson Karolinska Institute
Volker M. Lauschke
Volker M. Lauschke Karolinska Institute
Leif Bertilsson
Leif Bertilsson Karolinska University Hospital
Jan-Åke Gustafsson
Jan-Åke Gustafsson University of Houston
Tommy B. Andersson
Tommy B. Andersson AstraZeneca (United Kingdom)
Marja-Liisa Dahl
Marja-Liisa Dahl Karolinska University Hospital
Emanuele Albano
Emanuele Albano University of Eastern Piedmont Amadeo Avogadro
Cristina Rodríguez-Antona
Cristina Rodríguez-Antona Alberto Sols Biomedical Research Institute
Thomas M. Badger
Thomas M. Badger University of Arkansas for Medical Sciences
Martin J. J. Ronis
Martin J. J. Ronis Louisiana State University Health Sciences Center New Orleans

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