World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
12606
World Ranking
11402
National Ranking
218

Overview

Cristina Rodríguez-Antona is affiliated with the Alberto Sols Biomedical Research Institute in Spain. Their research spans multiple fields, predominantly in Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions in Molecular Biology, Pulmonary and Respiratory Medicine, Oncology, Cancer Research, and Surgery.

Their work includes a significant focus on topics related to renal cell carcinoma treatment, renal and related cancers, cancer genomics and diagnostics, ovarian cancer diagnosis and treatment, pharmacogenetics and drug metabolism, cancer, hypoxia, and metabolism, and bladder and urothelial cancer treatments.

Rodríguez-Antona has published extensively in various scientific journals. Frequent publication venues include:

  • Cancers
  • Clinical Pharmacology & Therapeutics
  • Journal of Clinical Oncology
  • Annals of Oncology
  • Clinical Cancer Research

Recent papers representing the scope and themes of their research include:

  • Effect of the Most Relevant CYP3A4 and CYP3A5 Polymorphisms on the Pharmacokinetic Parameters of 10 CYP3A Substrates, 2020, Biomedicines
  • Clinical Pharmacogenetics Implementation Consortium Guideline for the Use of Aminoglycosides Based on MT-RNR1 Genotype, 2021, Clinical Pharmacology & Therapeutics
  • Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma, 2023, Nature Communications
  • Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE), 2020, Clinical Cancer Research
  • Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma, 2024, Nature Cancer

Their research has involved collaborations with several frequent co-authors, including:

  • Mercedes Robledo
  • Jesús García-Donás
  • Javier Lanillos
  • María Santos
  • Alberto Cascón

Cristina Rodríguez-Antona's work contributes to advancing understanding and treatment approaches within oncology and pharmacogenetics, particularly regarding cancer metabolism, diagnostics, and therapeutic strategies. Their research outputs reflect integration of molecular biology and clinical applications across various cancer types and related diseases.

Best Publications

  • Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects

    Magnus Ingelman-Sundberg;Sarah C. Sim;Alvin Gomez;Cristina Rodriguez-Antona

  • Cytochrome P450 pharmacogenetics and cancer.

    C Rodriguez-Antona;M Ingelman-Sundberg

  • Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma

    Iñaki Comino-Méndez;Francisco J Gracia-Aznárez;Francesca Schiavi;Iñigo Landa

  • Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells.

    C. Rodríguez-Antona;M. T. Donato;A. Boobis;R. J. Edwards

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study

    Jesus Garcia-Donas;Emilio Esteban;Luis Javier Leandro-García;Daniel E Castellano

  • Tumoral and tissue-specific expression of the major human beta-tubulin isotypes.

    Luis J. Leandro-García;Susanna Leskelä;Iñigo Landa;Cristina Montero-Conde

  • The miR-200 family controls beta-tubulin III expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients.

    Susanna Leskelä;Luis J Leandro-García;Marta Mendiola;Jorge Barriuso

  • Whole-Exome Sequencing Identifies MDH2 as a New Familial Paraganglioma Gene

    Alberto Cascón;Iñaki Comino-Méndez;María Currás-Freixes;Aguirre A. de Cubas

  • Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas

    Elena López-Jiménez;Gonzalo Gómez-López;L Javier Leandro-García;Iván Muñoz

  • Pharmacogenetics of drug-metabolizing enzymes: implications for a safer and more effective drug therapy

    Magnus Ingelman-Sundberg;Cristina Rodriguez-Antona

  • The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

    Iñigo Landa;Sergio Ruiz-Llorente;Cristina Montero-Conde;Lucía Inglada-Pérez

  • Cytochrome P-450 mRNA expression in human liver and its relationship with enzyme activity.

    Cristina Rodríguez-Antona;M.Teresa Donato;Eugenia Pareja;Maria-José Gómez-Lechón

  • Tumoral EPAS1 (HIF2A) mutations explain sporadic pheochromocytoma and paraganglioma in the absence of erythrocytosis

    Iñaki Comino-Méndez;Aguirre A. de Cubas;Carmen Bernal;Cristina Álvarez-Escolá

  • Genetics of pheochromocytoma and paraganglioma in Spanish patients.

    Alberto Cascón;Guillermo Pita;Nelly Burnichon;Iñigo Landa

  • Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity

    S Leskelä;C Jara;L J Leandro-García;A Martínez

  • Pazopanib in pretreated advanced neuroendocrine tumors: a phase II, open-label trial of the Spanish Task Force Group for Neuroendocrine Tumors (GETNE)

    E. Grande;J. Capdevila;D. Castellano;A. Teulé

  • Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.

    Maria Karlgren;Alvin Gomez;Katarina Stark;Jenny Svärd

  • Phenotype-genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles.

    Cristina Rodríguez-Antona;Jane G. Sayi;Lars L. Gustafsson;Leif Bertilsson

  • Overexpression and activation of EGFR and VEGFR2 in medullary thyroid carcinomas is related to metastasis

    Cristina Rodríguez-Antona;Judith Pallares;Cristina Montero-Conde;Lucia Inglada-Pérez

Frequent Co-Authors

Magnus Ingelman-Sundberg
Magnus Ingelman-Sundberg Karolinska Institute
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Peter A. Fasching
Peter A. Fasching University of Erlangen-Nuremberg
Graham G. Giles
Graham G. Giles University of Melbourne
Javier Benitez
Javier Benitez Instituto de Salud Carlos III
Hans Gelderblom
Hans Gelderblom Leiden University Medical Center
Henk-Jan Guchelaar
Henk-Jan Guchelaar Leiden University Medical Center
Brian I. Rini
Brian I. Rini Vanderbilt University Medical Center
Susan J. Ramus
Susan J. Ramus University of New South Wales
Felix Beuschlein
Felix Beuschlein University of Zurich

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