World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
73
Citations
27595
World Ranking
5817
National Ranking
2752

Research.com Recognitions

  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

J. Marie Hardwick is affiliated with Johns Hopkins University in the United States and has contributed extensively to research in the fields of medicine, biochemistry, genetics, molecular biology, agricultural and biological sciences. Their research spans several key subfields including epidemiology, plant science, molecular biology, immunology, and infectious diseases.

The scientist's work often intersects with topics related to fungal infections and studies, antifungal resistance and susceptibility, plant-microbe interactions and immunity, plant disease resistance and genetics, phytoplasmas and hemiptera pathogens, invertebrate immune response mechanisms, and toxin mechanisms and immunotoxins.

Recent publications by Hardwick include:

  • Apoptotic cell death in disease-Current understanding of the NCCD 2023, 2023, published in Cell Death and Differentiation
  • Galleria mellonella immune melanization is fungicidal during infection, 2022, published in Communications Biology
  • Yeast cell death pathway requiring AP-3 vesicle trafficking leads to vacuole/lysosome membrane permeabilization, 2022, published in Cell Reports
  • Programmed Cell Death in Unicellular Versus Multicellular Organisms, 2023, published in Annual Review of Genetics
  • Cryptococcus neoformans rapidly invades the murine brain by sequential breaching of airway and endothelial tissues barriers, followed by engulfment by microglia, 2024, published in mBio

Hardwick frequently collaborates with other researchers, with notable co-authors being Madhura Kulkarni, Arturo Casadevall, Daniel F. Q. Smith, Quigly Dragotakes, and Xinchen Teng.

Their publications appear primarily in venues such as bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, Cell Death and Differentiation, Communications Biology, and Annual Review of Genetics.

Hardwick has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS), an award received in 2004.

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Conversion of Bcl-2 to a Bax-like Death Effector by Caspases

    Emily H.-Y. Cheng;Emily H.-Y. Cheng;David G. Kirsch;David G. Kirsch;Rollie J. Clem;Rollie J. Clem;Rajani Ravi;Rajani Ravi

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.

    C S Duckett;V E Nava;R W Gedrich;R J Clem

  • Multiple Functions of BCL-2 Family Proteins

    J. Marie Hardwick;Lucian Soane

  • Modulation of cell death by Bcl-XL through caspase interaction.

    Rollie J. Clem;Rollie J. Clem;Emily H.-Y. Cheng;Emily H.-Y. Cheng;Christopher L. Karp;David G. Kirsch

  • Caspase-3-dependent Cleavage of Bcl-2 Promotes Release of Cytochrome c

    David G. Kirsch;Andrea Doseff;B. Nelson Chau;Dae-Sik Lim

  • Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene

    B. Levine;Qi Huang;J. T. Isaacs;J. C. Reed

  • Bax-independent inhibition of apoptosis by Bcl-XL

    Emily H Y Cheng;Beth Levine;Lawrence H. Boise;Craig B. Thompson

  • A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak

    Emily H.Y. Cheng;John Nicholas;David S. Bellows;Gary S. Hayward

  • Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria

    Brian M. Polster;Brian M. Polster;Gorka Basañez;Aitor Etxebarria;J. Marie Hardwick

  • Antibody-mediated clearance of alphavirus infection from neurons.

    Beth Levine;J. Marie Hardwick;Bruce D. Trapp;Thomas O. Crawford

  • Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

    R K Srivastava;Q S Mi;J M Hardwick;D L Longo

  • Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase

    Kambiz N. Alavian;Hongmei Li;Leon Collis;Laura Bonanni

  • Mitochondrial fission proteins regulate programmed cell death in yeast

    Yihru Fannjiang;Wen Chih Cheng;Sarah J. Lee;Bing Qi

  • Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1.

    B.Nelson Chau;Emily H.-Y. Cheng;Douglas A. Kerr;J.Marie Hardwick

  • Bax-type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer Curvature

    Gorka Basañez;Juanita C. Sharpe;Jennifer Galanis;Teresa B. Brandt

  • Bcl-XL induces Drp1-dependent synapse formation in cultured hippocampal neurons

    Hongmei Li;Yingbei Chen;Adrienne F. Jones;Richard H. Sanger

  • Bcl-xL increases mitochondrial fission, fusion, and biomass in neurons

    Sarah B. Berman;Sarah B. Berman;Ying Bei Chen;Bing Qi;J. Michael McCaffery

  • Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins

    Tae Woo Kim;Chien Fu Hung;Morris Ling;Jeremy Juang

Frequent Co-Authors

Emily H. Cheng
Emily H. Cheng Memorial Sloan Kettering Cancer Center
Leonard K. Kaczmarek
Leonard K. Kaczmarek Yale University
Diane E. Griffin
Diane E. Griffin Johns Hopkins University
Michael J. Betenbaugh
Michael J. Betenbaugh Johns Hopkins University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Rollie J. Clem
Rollie J. Clem Kansas State University
Peter Smith
Peter Smith University of Aberdeen
Stuart A. Lipton
Stuart A. Lipton Scripps Research Institute
Laura Bonanni
Laura Bonanni University of Chieti-Pescara
Valina L. Dawson
Valina L. Dawson Johns Hopkins University School of Medicine

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