D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 98 Citations 56,024 170 World Ranking 450 National Ranking 265

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Apoptosis

His primary areas of investigation include Cell biology, Mitochondrion, Apoptosis, mitochondrial fusion and Mitochondrial fission. His Cell biology study combines topics in areas such as Molecular biology, Programmed cell death, Mitophagy and Bcl-2-associated X protein. Richard J. Youle combines subjects such as Parkin and Unfolded protein response with his study of Mitophagy.

In his research, Flip, Cytoplasm and Transport protein is intimately related to Bacterial outer membrane, which falls under the overarching field of Mitochondrion. The mitochondrial fusion study combines topics in areas such as Translocase of the inner membrane and Mitochondrial carrier. His research in Mitochondrial fission focuses on subjects like FIS1, which are connected to MFN1, DNM1L and DNAJA3.

His most cited work include:

  • The BCL-2 protein family: opposing activities that mediate cell death (3340 citations)
  • Guidelines for the use and interpretation of assays for monitoring autophagy (3242 citations)
  • Parkin is recruited selectively to impaired mitochondria and promotes their autophagy (2609 citations)

What are the main themes of his work throughout his whole career to date?

Richard J. Youle focuses on Cell biology, Mitochondrion, Molecular biology, Biochemistry and Apoptosis. His Cell biology research incorporates elements of mitochondrial fusion, Programmed cell death, Mitophagy and Parkin. His research investigates the connection between Mitochondrion and topics such as Bcl-2-associated X protein that intersect with problems in Bcl-2 Homologous Antagonist-Killer Protein.

The study incorporates disciplines such as Transferrin receptor, Immunotoxin, Cytotoxicity and Ricin in addition to Molecular biology. His Immunotoxin study incorporates themes from Pharmacology, Diphtheria toxin and Pathology. In his study, Mitochondrial membrane transport protein is inextricably linked to DNAJA3, which falls within the broad field of Mitochondrial fission.

He most often published in these fields:

  • Cell biology (56.98%)
  • Mitochondrion (36.60%)
  • Molecular biology (21.51%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cell biology (56.98%)
  • Mitochondrion (36.60%)
  • Mitophagy (16.60%)

In recent papers he was focusing on the following fields of study:

Cell biology, Mitochondrion, Mitophagy, Parkin and PINK1 are his primary areas of study. His Cell biology study integrates concerns from other disciplines, such as Autophagy, Autophagosome and Biogenesis. His Mitochondrion study combines topics in areas such as Genome, Mitochondrial Degradation, Mitochondrial DNA and Cytosol.

His research in Mitophagy intersects with topics in Mutation, Unfolded protein response, Mitochondrial matrix and Rab. His Parkin research integrates issues from Ubiquitin ligase and White. His studies in PINK1 integrate themes in fields like Endogeny, Chaperone and In vivo.

Between 2012 and 2021, his most popular works were:

  • The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy (1129 citations)
  • The Roles of PINK1, Parkin and Mitochondrial Fidelity in Parkinson's Disease (980 citations)
  • PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity (670 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

Richard J. Youle mostly deals with Cell biology, Mitophagy, PINK1, Parkin and Mitochondrion. Richard J. Youle has included themes like Autophagy and FIS1 in his Cell biology study. His Mitophagy study combines topics from a wide range of disciplines, such as Genome and Bioinformatics.

His PINK1 research is multidisciplinary, relying on both Cancer research and Transcription factor, TFEB. His research in Parkin focuses on subjects like Ubiquitin ligase, which are connected to Substantia nigra, Parkinsonism, Microphthalmia-associated transcription factor and ATG5. The concepts of his Mitochondrion study are interwoven with issues in Cell, Mitochondrial Degradation, Cytosol, Unfolded protein response and Programmed cell death.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Autophagy (2012)

7068 Citations

The BCL-2 protein family: opposing activities that mediate cell death

Richard J. Youle;Andreas Strasser.
Nature Reviews Molecular Cell Biology (2008)

4689 Citations

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Derek P. Narendra;Atsushi Tanaka;Der-Fen Suen;Richard J Youle.
Journal of Cell Biology (2008)

3244 Citations

Movement of Bax from the Cytosol to Mitochondria during Apoptosis

Keith G. Wolter;Yi-Te Hsu;Carolyn L. Smith;Amotz Nechushtan.
Journal of Cell Biology (1997)

2628 Citations

Mitochondrial Fission, Fusion, and Stress

Richard J. Youle;Alexander M. van der Bliek.
Science (2012)

2608 Citations

Mechanisms of mitophagy

Richard J. Youle;Derek P. Narendra;Derek P. Narendra.
Nature Reviews Molecular Cell Biology (2011)

2492 Citations

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.

Derek P. Narendra;Seok Min Jin;Atsushi Tanaka;Der Fen Suen.
PLOS Biology (2010)

2284 Citations

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis.

Stephan Frank;Brigitte Gaume;Elke S. Bergmann-Leitner;Wolfgang W. Leitner.
Developmental Cell (2001)

2049 Citations

Cytosol-to-membrane redistribution of Bax and Bcl-XL during apoptosis

Yi-Te Hsu;Keith G. Wolter;Richard J. Youle.
Proceedings of the National Academy of Sciences of the United States of America (1997)

1579 Citations

The Role of Mitochondria in Apoptosis

Chunxin Wang;Richard J. Youle.
Annual Review of Genetics (2009)

1509 Citations

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