World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
111
Citations
73081
World Ranking
507
National Ranking
260

Overview

Mark R. Cookson is affiliated with the National Institutes of Health in the United States. Their work spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a strong focus on molecular biology and neurology.

The scientist has contributed notably to research on neurodegenerative diseases, particularly Parkinson's disease mechanisms and treatments. Other key research topics include neurological diseases and metabolism, cellular transport and secretion, lysosomal storage disorders, Alzheimer's disease research and treatments, CRISPR and genetic engineering, and single-cell and spatial transcriptomics.

Frequent co-authors in their collaborative efforts include Andrew Singleton, Cornelis Blauwendraat, J. Raphael Gibbs, Mike A. Nalls, and Alexandra Beilina.

Cookson's recent papers demonstrate involvement in high-impact studies across a range of prestigious journals. These papers include:

  • Hallmarks of neurodegenerative diseases (2023), published in Cell
  • LRRK2 mediates tubulation and vesicle sorting from lysosomes (2020), published in Science Advances
  • A reference human induced pluripotent stem cell line for large-scale collaborative studies (2022), published in Cell Stem Cell
  • Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome (2021), published in Nature Communications
  • Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets (2021), published in JAMA Neurology

The scientist's publications are frequently found in prominent venues such as bioRxiv (Cold Spring Harbor Laboratory), Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Zenodo (CERN European Organization for Nuclear Research), Nature Communications, and the Journal of Parkinson's Disease.

Mark R. Cookson's research primarily intersects the fields of biochemistry, genetics, molecular biology, and medicine, with detailed work in molecular biology and neurology. Subfields include physiology, cell biology, and genetics. Their subject matter expertise clearly spans complex biological systems related to neurodegeneration and cellular transport mechanisms.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • α-Synuclein Locus Triplication Causes Parkinson's Disease

    A. B. Singleton;M. Farrer;J. Johnson;A. Singleton

  • PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.

    Derek P. Narendra;Seok Min Jin;Atsushi Tanaka;Der Fen Suen

  • Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

    Mike A Nalls;Cornelis Blauwendraat;Costanza L Vallerga;Karl Heilbron

  • Genome-wide association study reveals genetic risk underlying Parkinson's disease

    Javier Simón-Sánchez;Claudia Schulte;Jose M Bras;Jose M Bras;Manu Sharma

  • The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.

    Rosa M. Canet-Avilés;Mark A. Wilson;David W. Miller;Rili Ahmad

  • Common genetic variants influence human subcortical brain structures.

    Derrek P. Hibar;Jason L. Stein;Jason L. Stein;Miguel E. Renteria;Alejandro Arias-Vasquez

  • Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

    J. Raphael Gibbs;J. Raphael Gibbs;Marcel P. van der Brug;Marcel P. van der Brug;Dena G. Hernandez;Dena G. Hernandez;Bryan J. Traynor

  • Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.

    Elisa Greggio;Shushant Jain;Ann Kingsbury;Rina Bandopadhyay

  • THE BIOCHEMISTRY OF PARKINSON'S DISEASE*

    Mark R. Cookson

  • The transcriptional landscape of age in human peripheral blood

    Marjolein J. Peters;Roby Joehanes;Luke C. Pilling;Claudia Schurmann;Claudia Schurmann

  • An In Vitro Model of Parkinson's Disease: Linking Mitochondrial Impairment to Altered α-Synuclein Metabolism and Oxidative Damage

    Todd B. Sherer;Ranjita Betarbet;Amy K. Stout;Serena Lund

  • Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons.

    Leonard Petrucelli;Casey O'Farrell;Paul J. Lockhart;Melisa Baptista

  • Genetic variability in the regulation of gene expression in ten regions of the human brain

    Adaikalavan Ramasamy;Adaikalavan Ramasamy;Daniah Trabzuni;Sebastian Guelfi;Vibin Varghese

  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

    Günter U. Höglinger;Nadine M. Melhem;Dennis W. Dickson;Patrick M A Sleiman

  • α-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma

    Omar M. A. El-Agnaf;Sultan A. Salem;Katerina E. Paleologou;Leanne J. Cooper

  • The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson’s disease

    Mark R. Cookson

  • Evidence for natural antisense transcript-mediated inhibition of microRNA function

    Mohammad Ali Faghihi;Ming Zhang;Jia Huang;Farzaneh Modarresi

  • α-Synuclein and neuronal cell death

    Mark R Cookson

Frequent Co-Authors

Andrew B. Singleton
Andrew B. Singleton National Institutes of Health
John Hardy
John Hardy University College London
Dena G. Hernandez
Dena G. Hernandez National Institutes of Health
Patrick A. Lewis
Patrick A. Lewis University College London
J. Raphael Gibbs
J. Raphael Gibbs National Institutes of Health
Mina Ryten
Mina Ryten University College London
Mike A. Nalls
Mike A. Nalls National Institutes of Health
Sonja W. Scholz
Sonja W. Scholz National Institutes of Health
Bryan J. Traynor
Bryan J. Traynor National Institutes of Health
Adaikalavan Ramasamy
Adaikalavan Ramasamy A*STAR - Agency for Science, Technology and Research

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Genetics in the USA can open doors to a diverse range of career pathways, many of which intersect with health sciences and allied healthcare fields. For those interested in combining genetics with patient care, several nursing schools that dont require teas or HESI exams offer flexible entry points, making it easier to begin or advance a nursing career.

For learners aiming to fast-track their education, accelerated lpn programs are a great option—allowing you to qualify quickly for in-demand roles that often interface with genetic counselors and researchers. Leadership-minded students can benefit from mha online programs, which prepare graduates to manage healthcare organizations and contribute to policy making in fields influenced by genetic research.

For advanced research or academic careers, especially in genetic nursing or related specialties, pursuing phd nursing programs can lead to roles in higher education, research, and leadership. Each of these career pathways offers unique opportunities for those passionate about genetics and its impact on health and society.

Best Scientists Citing Mark R. Cookson

Trending Scientists