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Molecular Biology

D-Index
63
Citations
22030
World Ranking
1777
National Ranking
890

Overview

Stephen N. Jones is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with contributions also in Medicine.

Their work covers several specialized subfields, including Molecular Biology, Oncology, Cancer Research, Cardiology and Cardiovascular Medicine, and Hematology. The main topics explored in their publications encompass:

  • Cancer-related Molecular Pathways
  • Cancer, Hypoxia, and Metabolism
  • Retinoids in leukemia and cellular processes
  • Lipid metabolism and disorders
  • Blood Coagulation and Thrombosis Mechanisms
  • Protist diversity and phylogeny
  • Microtubule and mitosis dynamics

Stephen N. Jones has published research in several venues, including:

  • UNC Libraries
  • Proceedings of the National Academy of Sciences
  • Environmental Research Letters

Some of their recent papers are:

  • Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis, 2021, Proceedings of the National Academy of Sciences
  • Human Genome-Wide Association and Mouse Knockout Approaches Identify Platelet Supervillin as an Inhibitor of Thrombus Formation Under Shear Stress, 2020, UNC Libraries
  • Conditional Aurora A deficiency differentially affects early mouse embryo patterning, 2020, UNC Libraries
  • Identifying parameters impacting WASH STEM education across the globe, 2024, Environmental Research Letters

The scientist has frequently collaborated with several co-authors, including:

  • Loretah Chibaya
  • Baktiar Karim
  • Hong Zhang
  • Leonard C. Edelstein
  • Elizabeth J. Luna

Best Publications

  • Regulation of p53 stability by Mdm2

    Michael H. G. Kubbutat;Stephen N. Jones;Karen H. Vousden

  • Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway

    Cathy Tournier;Patricia M. Hess;Derek D. Yang;Jie Xu

  • p53 mutant mice that display early ageing-associated phenotypes

    Stuart D. Tyner;Sundaresan Venkatachalam;Jene Choi;Stephen Jones

  • Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

    Stephen N. Jones;Amy E. Roe;Lawrence A. Donehower;Allan Bradley

  • Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation.

    Sundaresan Venkatachalam;Yu‐Ping Shi;Stephen N. Jones;Hannes Vogel

  • MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

    Cathy Tournier;Chen Dong;Tod K. Turner;Stephen N. Jones

  • JNK targets p53 ubiquitination and degradation in nonstressed cells

    Serge Y. Fuchs;Victor Adler;Thomas Buschmann;Zhimin Yin

  • Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

    Stephen N. Jones;Amy R. Hancock;Hannes Vogel;Lawrence A. Donehower

  • Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue.

    Huiling Liang;Qin Chen;Andrew H. Coles;Stephen J. Anderson

  • Disruption of Ini1 Leads to Peri-Implantation Lethality and Tumorigenesis in Mice

    Cynthia J. Guidi;Arthur T. Sands;Brian P. Zambrowicz;Tod K. Turner

  • Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice

    Scott Houghtaling;Cynthia Timmers;Meenakshi Noll;Milton J. Finegold

  • The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.

    Xiongbin Lu;Ou Ma;Thuy Ai Nguyen;Stephen N. Jones

  • Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development.

    Je Yong Choi;Je Yong Choi;Jitesh Pratap;Amjad Javed;S. Kaleem Zaidi

  • Requirement of the JIP1 scaffold protein for stress-induced JNK activation

    Alan J. Whitmarsh;Chia-Yi Kuan;Norman J. Kennedy;Nyaya Kelkar

  • Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene.

    Hicham Drissi;Quyen Luc;A. Rauf Shakoori;Susana Chuva De Sousa Lopes

  • Osteoblast differentiation and skeletal development are regulated by Mdm2–p53 signaling

    Christopher J. Lengner;Heather Anne Steinman;James Gagnon;Thomas W. Smith

  • Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

    Rajini R. Mudhasani;Zhiqing Zhu;Gyorgy Hutvagner;Christine M. Eischen

  • Phosphorylation of Serine 18 Regulates Distinct p53 Functions in Mice

    Hayla Karen Sluss;Heather L. Armata;Judith Gallant;Stephen N. Jones

  • Suppression of Ras-stimulated transformation by the JNK signal transduction pathway

    Norman J. Kennedy;Hayla Karen Sluss;Stephen N. Jones;Dafna Bar-Sagi

  • Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice

    JongDae Shin;Michael Bossenz;Michael Bossenz;Young Chung;Hong Ma

Frequent Co-Authors

Gary S. Stein
Gary S. Stein University of Vermont
Jane B. Lian
Jane B. Lian University of Vermont
Janet L. Stein
Janet L. Stein University of Vermont
Anthony N. Imbalzano
Anthony N. Imbalzano University of Massachusetts Chan Medical School
Lawrence A. Donehower
Lawrence A. Donehower Baylor College of Medicine
Andre J. Van Wijnen
Andre J. Van Wijnen University of Connecticut Health Center
Allan Bradley
Allan Bradley University of Cambridge
Xiongbin Lu
Xiongbin Lu Indiana University
Markus Grompe
Markus Grompe Oregon Health & Science University
C. Thomas Caskey
C. Thomas Caskey Baylor College of Medicine

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