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Genetics

D-Index
101
Citations
46226
World Ranking
720
National Ranking
365

Research.com Recognitions

  • 2010 - Fellow of the Royal Society of Canada Academy of Science
  • 1993 - Member of the National Academy of Sciences
  • 1990 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1989 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

C. Thomas Caskey was affiliated with Baylor College of Medicine in the United States. Their research primarily spanned the fields of biochemistry, genetics, and molecular biology, with a focus on genetics and molecular biology subfields. Other areas of study included cellular and molecular neuroscience, cardiology and cardiovascular medicine, and cognitive neuroscience.

Their scientific work covered a range of topics, including:

  • Metabolomics and mass spectrometry studies
  • Genomics and rare diseases
  • Bioinformatics and genomic networks
  • Genetic associations and epidemiology
  • Gut microbiota and health
  • Nutrition, genetics, and disease
  • Genetic neurodegenerative diseases

Caskey's publication record included several papers, among them:

  • Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging (2020), published in Proceedings of the National Academy of Sciences
  • An unsupervised learning approach to identify novel signatures of health and disease from multimodal data (2020), published in Genome Medicine
  • 2021 Allan Award (2022), published in The American Journal of Human Genetics
  • Stephen T. Warren: Human geneticist who advanced understanding of mutational mechanisms and developmental disorders (2021), published in Proceedings of the National Academy of Sciences

Frequent co-authors of Caskey included:

  • Ying-Chen Claire Hou
  • Hung-Chun Yu
  • Elizabeth T. Cirulli
  • Natalie M. Schenker-Ahmed
  • Michael Hicks

The majority of their publications appeared in the following venues:

  • Proceedings of the National Academy of Sciences
  • Genome Medicine
  • The American Journal of Human Genetics

Throughout their career, Caskey received several recognitions:

  • Member of the National Academy of Sciences (1993)
  • Member of the National Academy of Medicine (NAM) (1989)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1990)
  • Fellow of the Royal Society of Canada (2010)
  • Member of the Association of American Physicians

Best Publications

  • Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

    Annemiske J.M.H. Verkerk;Maura Pieretti;James S. Sutcliffe;Ying-Hui Fu

  • Variation of the CGG repeat at the fragile X site results in genetic instability: resolution of the Sherman paradox.

    Ying-Hui Fu;Derek P.A. Kuhl;Antonio Pizzuti;Maura Pieretti

  • Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups.

    Al Edwards;Holly A. Hammond;Li Jin;C.Thomas Caskey;C.Thomas Caskey

  • DNA typing and genetic mapping with trimeric and tetrameric tandem repeats.

    A. I. Edwards;A. Civitello;H. A. Hammond;C. T. Caskey

  • An unstable triplet repeat in a gene related to myotonic muscular dystrophy.

    Y. H. Fu;A. Pizzuti;R. G. Fenwick;J. King

  • Absence of expression of the FMR-1 gene in fragile X syndrome.

    Maura Pieretti;Fuping Zhang;Ying-Hui Fu;Stephen T. Warren

  • Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeats

    Orly Reiner;Romeo Carrozzo;Ying Shen;Manfred Wehnert

  • DNA methylation represses FMR-1 transcription in fragile X syndrome

    Sutcliffe Js;Nelson Dl;Zhang F;Pieretti M

  • Identification of the gene responsible for Best macular dystrophy

    K. Petrukhin;M. J. Koisti;B. Bakall;Wen Li

  • Alu polymerase chain reaction: a method for rapid isolation of human-specific sequences from complex DNA sources.

    D L Nelson;S A Ledbetter;L Corbo;M F Victoria

  • A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase

    S Kochanek;P R Clemens;K Mitani;H H Chen

  • Two independent mutational events in the loss of urate oxidase during hominoid evolution.

    Xiangwei Wu;D. M. Muzny;Cheng Chi Lee;C. T. Caskey

  • Evaluation of 13 short tandem repeat loci for use in personal identification applications.

    H. A. Hammond;Li Jin;Y. Zhong;C. T. Caskey

  • Identification of receptors for neuromedin U and its role in feeding

    Andrew D. Howard;Ruiping Wang;Sheng-Shung Pong;Theodore N. Mellin

  • Identification of a (CUG)n Triplet Repeat RNA-Binding Protein and Its Expression in Myotonic Dystrophy

    Lubov T. Timchenko;Jill W. Miller;Nikolaj A. Timchenko;Druery R. DeVore

  • Triplet Repeat Mutations in Human Disease

    C. T. Caskey;A. Pizzuti;Ying-Hui Fu;R. G. Fenwick

  • Generation of cDNA probes directed by amino acid sequence: cloning of urate oxidase

    Cheng Chi Lee;Xiangwei Wu;Richard A. Gibbs;Richard G. Cook

  • Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.

    D W Melton;D S Konecki;J Brennand;C T Caskey

  • Automated DNA sequencing of the human HPRT locus

    A Edwards;H Voss;P Rice;A Civitello

  • Urate oxidase: primary structure and evolutionary implications.

    Xiangwei Wu;Cheng Chi Lee;D. M. Muzny;C. T. Caskey

Frequent Co-Authors

J. Craig Venter
J. Craig Venter J. Craig Venter Institute
John W. Belmont
John W. Belmont Baylor College of Medicine
Ewen F. Kirkness
Ewen F. Kirkness J. Craig Venter Institute
David L. Nelson
David L. Nelson Baylor College of Medicine
Amalio Telenti
Amalio Telenti VIR Biotechnology (United States)
Jeffrey S. Chamberlain
Jeffrey S. Chamberlain University of Washington
Elizabeth T. Cirulli
Elizabeth T. Cirulli Duke University
Stephen T. Warren
Stephen T. Warren Emory University
Richard A. Gibbs
Richard A. Gibbs Baylor College of Medicine
Tim D. Spector
Tim D. Spector King's College London

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