D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 93 Citations 25,789 308 World Ranking 6828 National Ranking 3703
Molecular Biology D-index 94 Citations 26,685 304 World Ranking 383 National Ranking 220

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Internal medicine

Jeffrey S. Chamberlain mostly deals with Duchenne muscular dystrophy, Dystrophin, Muscular dystrophy, Molecular biology and Cell biology. His Duchenne muscular dystrophy research integrates issues from Viral vector, Genetic enhancement and Pathology. His Dystrophin research is multidisciplinary, incorporating perspectives in Sarcolemma and Exon.

His Muscular dystrophy research includes elements of Transgene, Bioinformatics, Anatomy, Skeletal muscle and Side population. His study in Anatomy is interdisciplinary in nature, drawing from both Endocrinology and Internal medicine, Isometric exercise. His Molecular biology research incorporates elements of Cardiac muscle, Regulation of gene expression, Gene, Myocyte and Myosin.

His most cited work include:

  • Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplification (1146 citations)
  • Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells. (828 citations)
  • Systemic delivery of genes to striated muscles using adeno-associated viral vectors. (533 citations)

What are the main themes of his work throughout his whole career to date?

Jeffrey S. Chamberlain mainly investigates Dystrophin, Duchenne muscular dystrophy, Muscular dystrophy, Cell biology and Molecular biology. Jeffrey S. Chamberlain mostly deals with Utrophin in his studies of Dystrophin. His work carried out in the field of Duchenne muscular dystrophy brings together such families of science as Genetic enhancement, Bioinformatics and Skeletal muscle.

His Genetic enhancement research incorporates themes from Vector, Viral vector, Transgene and Virology. His studies deal with areas such as Dystrophy, Pathology, Immunology and Gene delivery as well as Muscular dystrophy. His Molecular biology research includes themes of Gene expression, Transfection, Complementary DNA, Exon and Adenoviridae.

He most often published in these fields:

  • Dystrophin (53.73%)
  • Duchenne muscular dystrophy (51.04%)
  • Muscular dystrophy (35.82%)

What were the highlights of his more recent work (between 2014-2021)?

  • Duchenne muscular dystrophy (51.04%)
  • Dystrophin (53.73%)
  • Genetic enhancement (24.78%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Duchenne muscular dystrophy, Dystrophin, Genetic enhancement, Cell biology and Bioinformatics. His research integrates issues of Adeno-associated virus, Cardiomyopathy, Anatomy, Skeletal muscle and Muscular dystrophy in his study of Duchenne muscular dystrophy. His Muscular dystrophy study combines topics in areas such as Degenerative disease and Pathology.

Jeffrey S. Chamberlain has researched Dystrophin in several fields, including Sarcolemma, Vector and Genome editing. His Genetic enhancement study incorporates themes from Internal medicine, Clinical trial, Viral vector and Virology. His study in the field of Function, Progenitor cell and Myocyte is also linked to topics like Nebulin.

Between 2014 and 2021, his most popular works were:

  • Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy. (206 citations)
  • High levels of AAV vector integration into CRISPR-induced DNA breaks (77 citations)
  • Cas9 immunity creates challenges for CRISPR gene editing therapies. (71 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Internal medicine

The scientist’s investigation covers issues in Dystrophin, Duchenne muscular dystrophy, Genetic enhancement, Muscular dystrophy and Cell biology. The Dystrophin study combines topics in areas such as Exon skipping, Actin cytoskeleton, Spectrin and Gene isoform. His studies in Duchenne muscular dystrophy integrate themes in fields like Adeno-associated virus and CRISPR.

His Genetic enhancement research is multidisciplinary, relying on both Histology, Pathology, Viral vector and Bioinformatics. The various areas that he examines in his Muscular dystrophy study include Ex vivo, Binding site, Muscle contraction and Creatine kinase. His work deals with themes such as Vector, In vivo and Skeletal muscle, which intersect with Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Deletion screening of the Duchenne muscular dystrophy locus via multiplex DNA amplification

Jeffrey S. Chamberlain;Richard A. Gibbs;Joel E. Rainer;Phi Nga Nguyen;Phi Nga Nguyen.
Nucleic Acids Research (1988)

1907 Citations

Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells.

Arianna Dellavalle;Maurilio Sampaolesi;Rossana Tonlorenzi;Enrico Tagliafico.
Nature Cell Biology (2007)

1074 Citations

Systemic delivery of genes to striated muscles using adeno-associated viral vectors.

Paul Gregorevic;Michael J Blankinship;James M Allen;Robert W Crawford.
Nature Medicine (2004)

708 Citations

Modular flexibility of dystrophin: Implications for gene therapy of Duchenne muscular dystrophy

Scott Q. Harper;Michael A. Hauser;Michael A. Hauser;Christiana DelloRusso;Christiana DelloRusso;Dongsheng Duan.
Nature Medicine (2002)

629 Citations

X-linked dilated cardiomyopathy. Molecular genetic evidence of linkage to the Duchenne muscular dystrophy (dystrophin) gene at the Xp21 locus.

J. A. Towbin;J. F. Hejtmancik;P. Brink;B. Gelb.
Circulation (1993)

589 Citations

Animal models for muscular dystrophy show different patterns of sarcolemmal disruption

Volker Straub;Jill A. Rafael;Jeffrey S. Chamberlain;Kevin P. Campbell.
Journal of Cell Biology (1997)

569 Citations

Identification and Characterization of the Dystrophin Anchoring Site on β-Dystroglycan

Daniel Jung;Bin Yang;Bin Yang;Jon Meyer;Jon Meyer;Jeffrey S. Chamberlain.
Journal of Biological Chemistry (1995)

417 Citations

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy

Yi Lai;Gail D. Thomas;Yongping Yue;Hsiao T. Yang.
Journal of Clinical Investigation (2009)

384 Citations

Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity

Gregory A. Cox;Neil M. Cole;Kiichiro Matsumura;Stephanie F. Phelps.
Nature (1993)

359 Citations

rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.

Paul Gregorevic;James M Allen;Elina Minami;Michael J Blankinship.
Nature Medicine (2006)

348 Citations

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