World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
56
Citations
10935
World Ranking
2207
National Ranking
54

Overview

Paul Gregorevic is affiliated with the University of Melbourne in Australia. Their research spans multiple disciplines within biochemistry, genetics, molecular biology, and medicine. The scientist has contributed extensively to both main and subfields, focusing particularly on molecular biology, cardiology and cardiovascular medicine, physiology, genetics, and surgery.

Their work covers key topics including muscle physiology and disorders, adipose tissue and metabolism, ubiquitin and proteasome pathways, nutrition and health in aging, RNA research and splicing, RNA modifications and cancer, as well as pancreatic function and diabetes.

Paul Gregorevic has published in a variety of scientific venues, frequently contributing to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Physiology-Cell Physiology
  • Molecular & Cellular Proteomics
  • Heart Lung and Circulation
  • Nature Communications

The scientist has collaborated regularly with several coauthors, including:

  • Hongwei Qian
  • Kevin I. Watt
  • Craig A. Goodman
  • Helen Kiriazis
  • Benjamin L. Parker

Notable recent publications include:

  • "Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia," 2021, published in Science Translational Medicine
  • "Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function," 2022, published in Cell Metabolism
  • "Fine-tuning the cardiac O-GlcNAcylation regulatory enzymes governs the functional and structural phenotype of the diabetic heart," 2021, published in Cardiovascular Research
  • "Sex-Specific Control of Human Heart Maturation by the Progesterone Receptor," 2021, published in Circulation
  • "Integrated Glycoproteomics Identifies a Role of N-Glycosylation and Galectin-1 on Myogenesis and Muscle Development," 2020, published in Molecular & Cellular Proteomics

Best Publications

  • Systemic delivery of genes to striated muscles using adeno-associated viral vectors.

    Paul Gregorevic;Michael J Blankinship;James M Allen;Robert W Crawford

  • Suppression of microRNA-29 expression by TGF-β1 promotes collagen expression and renal fibrosis.

    Bo Wang;Radko Komers;Rosemarie Carew;Catherine E. Winbanks

  • Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise

    Martin Whitham;Martin Whitham;Benjamin L. Parker;Martin Friedrichsen;Janne R. Hingst

  • Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

    Bianca C Bernardo;Xiao Ming Gao;Catherine E Winbanks;Esther J H Boey

  • Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

    Richard J. Mills;Drew M. Titmarsh;Xaver Koenig;Xaver Koenig;Benjamin L. Parker

  • rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice.

    Paul Gregorevic;James M Allen;Elina Minami;Michael J Blankinship

  • Efficient transduction of skeletal muscle using vectors based on adeno-associated virus serotype 6.

    Michael J. Blankinship;Paul Gregorevic;James M. Allen;Scott Q. Harper

  • TGF-β Regulates miR-206 and miR-29 to Control Myogenic Differentiation through Regulation of HDAC4

    Catherine E. Winbanks;Bo Wang;Claudia Beyer;Phillip Koh

  • Sustained AAV-mediated dystrophin expression in a canine model of Duchenne muscular dystrophy with a brief course of immunosuppression

    Zejing Wang;Christian S Kuhr;Christian S Kuhr;James M Allen;Michael Blankinship

  • Design of tissue-specific regulatory cassettes for high-level rAAV-mediated expression in skeletal and cardiac muscle.

    Maja Z. Salva;Charis L. Himeda;Phillip W L Tai;Eiko Nishiuchi

  • miR-21 promotes renal fibrosis in diabetic nephropathy by targeting PTEN and SMAD7

    Aaron D McClelland;Aaron D McClelland;Michal Herman-Edelstein;Radko Komers;Jay Chandra Jha

  • Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

    Catherine E. Winbanks;Kate L. Weeks;Rachel E. Thomson;Patricio V. Sepulveda;Patricio V. Sepulveda

  • The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

    Catherine E Winbanks;Justin Chen;Justin Chen;Justin Chen;Hongwei Qian;Yingying Liu

  • TGFβ and BMP signaling in skeletal muscle: potential significance for muscle-related disease

    Roberta Sartori;Paul Gregorevic;Marco Sandri

  • Elevated expression of activins promotes muscle wasting and cachexia

    Justin L. Chen;Justin L. Chen;Kelly L. Walton;Catherine E. Winbanks;Kate T. Murphy

  • ACTN3 genotype influences muscle performance through the regulation of calcineurin signaling.

    Jane T. Seto;Kate G.R. Quinlan;Monkol Lek;Xi Fiona Zheng

  • Systemic Microdystrophin Gene Delivery Improves Skeletal Muscle Structure and Function in Old Dystrophic mdx Mice

    Paul Gregorevic;Michael J Blankinship;James M Allen;Jeffrey S Chamberlain

  • The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size

    Kevin I. Watt;Bradley J. Turner;Adam Hagg;Xuehua Zhang

  • Systemic administration of micro-dystrophin restores cardiac geometry and prevents dobutamine-induced cardiac pump failure.

    De Wayne Townsend;Michael J. Blankinship;James M. Allen;Paul Gregorevic

  • Immunity to adeno-associated virus-mediated gene transfer in a random-bred canine model of Duchenne muscular dystrophy.

    Zejing Wang;James M Allen;Stanley R Riddell;Paul Gregorevic

Frequent Co-Authors

Jeffrey S. Chamberlain
Jeffrey S. Chamberlain University of Washington
Craig A. Harrison
Craig A. Harrison Monash University
Mark A. Febbraio
Mark A. Febbraio Monash University
David A. Williams
David A. Williams Boston Children's Hospital
Kathryn N. North
Kathryn N. North University of Melbourne
Martin N. Sillence
Martin N. Sillence Queensland University of Technology
David E. James
David E. James University of Sydney
Kate L Loveland
Kate L Loveland Hudson Institute of Medical Research
Peter J. Meikle
Peter J. Meikle Baker IDI Heart and Diabetes Institute
Stephen J. Tapscott
Stephen J. Tapscott Fred Hutchinson Cancer Research Center

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