Alvan C. Hengge

Overview

Best Publications

• Enzymatic mechanisms of phosphate and sulfate transfer.

  W. Wallace Cleland;Alvan C. Hengge

  490
  Citations

• Isotope effects in the study of phosphoryl and sulfuryl transfer reactions.

  Alvan C. Hengge

  242
  Citations

• Conformational motions regulate phosphoryl transfer in related protein tyrosine phosphatases

  Sean K. Whittier;Alvan C. Hengge;J. Patrick Loria

  229
  Citations

• Transition-State Structures for Phosphoryl- TransferReactions of p-Nitrophenyl Phosphate

  Alvan C. Hengge;William A. Edens;Hannah Elsing

  198
  Citations

• Nature of the transition state of the protein-tyrosine phosphatase-catalyzed reaction.

  Alvan C. Hengge;Gwendolyn A. Sowa;Li Wu;Zhong-Yin Zhang

  172
  Citations

• Insights into the reaction of protein-tyrosine phosphatase 1B: crystal structures for transition state analogs of both catalytic steps.

  Tiago A.S. Brandão;Alvan C. Hengge;Sean J. Johnson

  168
  Citations

• Mechanisms of phosphoryl and acyl transfer.

  W. W. Cleland;Alvan C. Hengge

  151
  Citations

• Characterization of Transition States in Dichloro (1,4,7-Triazacyclononane) Copper (II)-Catalyzed Activated Phosphate Diester Hydrolysis

  Kim A. Deal;and Alvan C. Hengge;Judith N. Burstyn

  140
  Citations

• CONCERTED OR STEPWISE MECHANISMS FOR ACYL TRANSFER REACTIONS OF P-NITROPHENYL ACETATE ? TRANSITION STATE STRUCTURES FROM ISOTOPE EFFECTS

  Alvan C. Hengge;Robert A. Hess

  139
  Citations

• Mechanistic Studies on Enzyme-Catalyzed Phosphoryl Transfer

  Alvan C. Hengge

  107
  Citations

• Physical Organic Perspectives on Phospho Group Transfer From Phosphates and Phosphinates

  Alvan C. Hengge;I. Onyido

  96
  Citations

• Loop Dynamics and Enzyme Catalysis in Protein Tyrosine Phosphatases

  Rory M. Crean;Michal Biler;Marc W. van der Kamp;Alvan C. Hengge

  92
  Citations

• DIrect measurement of transition-state bond cleavage in hydrolysis of phosphate esters of p-nitrophenol

  Alvan C. Hengge;W. W. Cleland

  91
  Citations

• Mechanism of Rhodium-Catalyzed Carbene Formation from Diazo Compounds

  Freeman M. Wong;Jianbo Wang;Alvan C. Hengge;Weiming Wu

  90
  Citations

• Transition-state structures for the native dual-specific phosphatase VHR and D92N and S131A mutants. Contributions to the driving force for catalysis.

  Alvan C. Hengge;John M. Denu;Jack E. Dixon

  90
  Citations

• An altered mechanism of hydrolysis for a metal-complexed phosphate diester.

  Tim Humphry;Marcello Forconi;Nicholas H. Williams;Alvan C. Hengge

  89
  Citations

• Studies of Transition-State Structures in PhosphorylTransfer Reactions of Phosphodiesters of p-Nitrophenol

  Alvan C. Hengge;Aleksandra E. Tobin;W. W. Cleland

  88
  Citations

• The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B.

  Tiago A.S. Brandão;Sean J. Johnson;Alvan C. Hengge

  88
  Citations

• Probing the origin of the compromised catalysis of E. coli alkaline phosphatase in its promiscuous sulfatase reaction.

  Irina Catrina;Patrick J. O'Brien;Jamie Purcell;Jamie Purcell;Ivana Nikolic-Hughes

  87
  Citations

• A concerted mechanism for the transfer of the thiophosphinoyl group from aryl dimethylphosphinothioate esters to oxyanionic nucleophiles in aqueous solution.

  Ikenna Onyido;Krzysztof Swierczek;Jamie Purcell;Alvan C. Hengge

  87
  Citations

• Altered transition state for the reaction of an RNA model catalyzed by a dinuclear zinc(II) catalyst.

  Tim Humphry;Subashree Iyer;Olga Iranzo;Janet R. Morrow

  86
  Citations

• Substrate Promoted Formation of a Catalytically Competent Binuclear Center and Regulation of Reactivity in a Glycerophosphodiesterase from Enterobacter aerogenes

  Kieran S. Hadler;Eric A. Tanifum;Sylvia Hsu-Chen Yip;Nataša Mitić

  82
  Citations