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Nathan Dascal

Nathan Dascal

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
9860
World Ranking
12800
National Ranking
121

Overview

Nathan Dascal is affiliated with Tel Aviv University in Israel and specializes in the field of Biochemistry, Genetics, and Molecular Biology. Their research primarily focuses on molecular biology, cellular and molecular neuroscience, cardiology and cardiovascular medicine, physiology, and psychiatry and mental health.

The main topics of Nathan Dascal's work include:

  • Ion channel regulation and function
  • Receptor mechanisms and signaling
  • Neuroscience and neuropharmacology research
  • Cardiac electrophysiology and arrhythmias
  • Ion transport and channel regulation
  • Protein kinase regulation and GTPase signaling
  • Neuroscience and neural engineering

Recent publications by Nathan Dascal demonstrate diverse aspects of ion channel regulation and neuroscience. These include:

  • Reconstitution of β-adrenergic regulation of Ca V 1.2: Rad-dependent and Rad-independent protein kinase A mechanisms (2021), published in Proceedings of the National Academy of Sciences
  • Andersen-Tawil Syndrome Is Associated With Impaired PIP2 Regulation of the Potassium Channel Kir2.1 (2020), published in Frontiers in Pharmacology
  • A novel small-molecule selective activator of homomeric GIRK4 channels (2022), published in Journal of Biological Chemistry
  • Encephalopathy-causing mutations in Gβ1 (GNB1) alter regulation of neuronal GIRK channels (2021), published in iScience
  • Epilepsy in a mouse model of GNB1 encephalopathy arises from altered potassium (GIRK) channel signaling and is alleviated by a GIRK inhibitor (2023), published in Frontiers in Cellular Neuroscience

Nathan Dascal frequently collaborates with several researchers, including:

  • Boris Shalomov
  • Haritha P. Reddy
  • Anna Stary-Weinzinger
  • Daniel Yakubovich
  • Theres Friesacher

The scientist's work has been prominently featured in several publication venues, with multiple contributions to:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Frontiers in Pharmacology
  • IBRO Neuroscience Reports

Best Publications

  • cAMP-Dependent Regulation of Cardiac L-Type Ca2+ Channels Requires Membrane Targeting of PKA and Phosphorylation of Channel Subunits

    Tianyan Gao;Atsuko Yatani;Mark L Dell'Acqua;Hidenori Sako

  • Atrial G protein-activated K+ channel: expression cloning and molecular properties.

    N Dascal;W Schreibmayer;N F Lim;W Wang

  • Expression and modulation of voltage-gated calcium channels after RNA injection in Xenopus oocytes

    Nathan Dascal;Terry P. Snutch;Hermann Lübbert;Norman Davidson

  • Primary structure and functional expression of a cyclic nucleotidegated channel from rabbit aorta

    Martin Biel;Wolfram Altenhofen;Roger Hullin;Jost Ludwig

  • The M2 muscarinic G-protein-coupled receptor is voltage-sensitive.

    Yair Ben-Chaim;Oded Tour;Nathan Dascal;Itzchak Parnas

  • Voltage clamping of xenopus laevis oocytes utilizing agarose-cushion electrodes

    Wolfgang Schreibmayer;Henry A. Lester;Nathan Dascal

  • Role of calcium mobilization in mediation of acetylcholine-evoked chloride currents in Xenopus laevis oocytes.

    N Dascal;B Gillo;Y Lass

  • Activation of protein kinase C alters voltage dependence of a Na+ channel.

    Nathan Dascal;Ilana Lotan

  • Inhibition of an inwardly rectifying K + channel by G-protein α-subunits

    Wolfgang Schreibmayer;Carmen W. Dessauer;Dmitry Vorobiov;Alfred G. Gilman

  • Tissue-specific expression of high-voltage-activated dihydropyridine-sensitive L-type calcium channels.

    Martin Biel;Martin Biel;Roger Hullin;Roger Hullin;Stefanie Freundner;Dafna Singer

  • Protein kinase A reduces voltage-dependent Na+ current in Xenopus oocytes.

    E Gershon;L Weigl;I Lotan;W Schreibmayer

  • Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes

    Nathan Dascal;Nancy F. Lim;Wolfgang Schreibmayer;Weizhen Wang

  • Regulation of cardiac L-type Ca²⁺ channel CaV1.2 via the β-adrenergic-cAMP-protein kinase A pathway: old dogmas, advances, and new uncertainties.

    Sharon Weiss;Shimrit Oz;Adva Benmocha;Nathan Dascal

  • Rat brain 5-HT1C receptors are encoded by a 5-6 kbase mRNA size class and are functionally expressed in injected Xenopus oocytes

    H Lubbert;TP Snutch;N Dascal;HA Lester

  • Distribution and localization of a G protein-coupled inwardly rectifying K+ channel in the rat

    Christine Karschin;Wolfgang Schreibmayer;Nathan Dascal;Henry Lester

  • Adenosine-induced slow ionic currents in the Xenopus oocyte.

    Ilana Lotan;Nathan Dascal;Sasson Cohen;Yoram Lass

  • A potential site of functional modulation by protein kinase A in the cardiac Ca2+ channel alpha 1C subunit.

    Tuvia Perets;Yakov Blumenstein;Elena Shistik;Ilana Lotan

  • Modulation of cardiac Ca2+ channels in Xenopus oocytes by protein kinase C.

    Dafna Singer-Lahat;Eli Gershon;Ilana Lotan;Roger Hullin

  • Expression of Exogenous Ion Channels and Neurotransmitter Receptors in RNA-Injected Xenopus Oocytes

    Nathan Dascal;Ilana Lotan

  • Phosphorylation by protein kinase A of RCK1 K+ channels expressed in Xenopus oocytes.

    Tatiana Ivanina;Tuvia Perets;William B. Thornhill;Gal Levin

Frequent Co-Authors

Henry A. Lester
Henry A. Lester California Institute of Technology
Norman Davidson
Norman Davidson California Institute of Technology
Veit Flockerzi
Veit Flockerzi Saarland University
Martin Biel
Martin Biel Ludwig-Maximilians-Universität München
Franz Hofmann
Franz Hofmann Technical University of Munich
Alfred G. Gilman
Alfred G. Gilman The University of Texas Southwestern Medical Center
Rudolf Zechner
Rudolf Zechner University of Graz
Arnold Schwartz
Arnold Schwartz University of Cincinnati
Oleg Krishtal
Oleg Krishtal National Academy of Sciences of Ukraine
Charles Chavkin
Charles Chavkin University of Washington

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