Diomedes E. Logothetis

Overview

Best Publications

• Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms

  David K Welsh;Diomedes E Logothetis;Markus Meister;Steven M Reppert

  1863
  Citations

• The βγ subunits of GTP-binding proteins activate the muscarinic K + channel in heart

  Diomedes E. Logothetis;Yoshihisa Kurachi;Jonas Galper;Eva J. Neer

  1553
  Citations

• Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons

  Mark R. Plummer;Diomedes E. Logothetis;Peter Hess

  782
  Citations

• PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain.

  Tibor Rohács;Tibor Rohács;Coeli M B Lopes;Ioannis Michailidis;Diomedes E Logothetis

  720
  Citations

• PIP2 Activates KCNQ Channels, and Its Hydrolysis Underlies Receptor-Mediated Inhibition of M Currents

  Hailin Zhang;Liviu C Craciun;Tooraj Mirshahi;Tibor Rohács

  623
  Citations

• Alterations in conserved Kir channel-PIP2 interactions underlie channelopathies.

  Coeli M.B. Lopes;Hailin Zhang;Tibor Rohacs;Taihao Jin

  470
  Citations

• Activation of inwardly rectifying K+ channels by distinct PtdIns(4,5)P2 interactions.

  Hailin Zhang;Cheng He;Xixin Yan;Tooraj Mirshahi

  386
  Citations

• Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs

  Miguel Fribourg;José L. Moreno;Terrell Holloway;Davide Provasi

  344
  Citations

• A region of adenylyl cyclase 2 critical for regulation by G protein beta gamma subunits

  Jianqiang Chen;Michael DeVivo;Jane Dingus;Anya Harry

  324
  Citations

• Activation of the atrial KACh channel by the βγ subunits of G proteins or intracellular Na+ ions depends on the presence of phosphatidylinositol phosphates

  Jin Liang Sui;Jérôme Petit-Jacques;Diomedes E. Logothetis

  285
  Citations

• Receptor-mediated hydrolysis of plasma membrane messenger PIP2 leads to K+-current desensitization.

  Evgeny Kobrinsky;Tooraj Mirshahi;Hailin Zhang;Taihao Jin

  258
  Citations

• Specificity of activation by phosphoinositides determines lipid regulation of Kir channels

  Tibor Rohács;Coeli M. B. Lopes;Taihao Jin;Pavan P. Ramdya

  232
  Citations

• Distinct specificities of inwardly rectifying K(+) channels for phosphoinositides.

  Tibor Rohács;Jian Chen;Glenn D. Prestwich;Diomedes E. Logothetis

  229
  Citations

• Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of Kir channels by diverse modulators

  Xiaona Du;Hailin Zhang;Hailin Zhang;Coeli M. B. Lopes;Tooraj Mirshahi

  226
  Citations

• PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels

  Coeli M. B. Lopes;Tibor Rohács;Gábor Czirják;Tamás Balla

  217
  Citations

• N‐terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits

  Kim W. Chan;Kim W. Chan;Hailin Zhang;Diomedes E. Logothetis

  212
  Citations

• Specificity of action of guanine nucleotide-binding regulatory protein subunits on the cardiac muscarinic K+ channel

  Diomedes E. Logothetis;Donghee Kim;John K. Northup;Eva J. Neer

  201
  Citations

• Incremental reductions of positive charge within the S4 region of a voltage-gated K+ channel result in corresponding decreases in gating charge.

  Diomedes E. Logothetis;Shahla Movahedi;Carol Satler;Klaus Lindpaintner

  199
  Citations

• Visualization of a Functional Gαq-Green Fluorescent Protein Fusion in Living Cells ASSOCIATION WITH THE PLASMA MEMBRANE IS DISRUPTED BY MUTATIONAL ACTIVATION AND BY ELIMINATION OF PALMITOYLATION SITES, BUT NOT BY ACTIVATION MEDIATED BY RECEPTORS OR AlF4 −

  Thomas E. Hughes;Hailin Zhang;Diomedes E. Logothetis;Catherine H. Berlot

  186
  Citations

• Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants.

  Michel Vivaudou;Kim W. Chan;Jin-Liang Sui;Lily Y. Jan

  177
  Citations