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D-Index & Metrics

Chemistry

D-Index
112
Citations
44163
World Ranking
741
National Ranking
35

Overview

Mark S.P. Sansom is affiliated with the University of Oxford in the United Kingdom. Their research primarily focuses on areas within Biochemistry, Genetics, and Molecular Biology, with a strong emphasis on Molecular Biology.

They explore several specialized subfields including Molecular Biology, Biomedical Engineering, Cellular and Molecular Neuroscience, Atomic and Molecular Physics and Optics, and Genetics.

Their work addresses multiple key topics, such as:

  • Lipid Membrane Structure and Behavior
  • Protein Structure and Dynamics
  • Nanopore and Nanochannel Transport Studies
  • Spectroscopy and Quantum Chemical Studies
  • RNA and protein synthesis mechanisms
  • Ion channel regulation and function
  • Neuroscience and Neuropharmacology Research

Mark S.P. Sansom has published extensively in several scientific venues. Their most frequent publication venues include:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Journal of Chemical Theory and Computation
  • ACS Nano

Their notable recent papers include:

  • "Water in Nanopores and Biological Channels: A Molecular Simulation Perspective," 2020, Chemical Reviews
  • "PyLipID: A Python Package for Analysis of Protein-Lipid Interactions from Molecular Dynamics Simulations," 2022, Journal of Chemical Theory and Computation
  • "Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs," 2020, Nature Communications
  • "Defining how multiple lipid species interact with inward rectifier potassium (Kir2) channels," 2020, Proceedings of the National Academy of Sciences
  • "Identification and assessment of cardiolipin interactions with E. coli inner membrane proteins," 2021, Science Advances

Frequent co-authors in Sansom's research include Robin A. Corey, T. Bertie Ansell, Phillip J. Stansfeld, Wanling Song, and Anna L. Duncan, indicating active collaboration in related fields.

Best Publications

  • HOLE: a program for the analysis of the pore dimensions of ion channel structural models.

    Oliver S. Smart;Joseph G. Neduvelil;Xiaonan Wang;B.A. Wallace

  • Computational Modeling of Realistic Cell Membranes

    Siewert J. Marrink;Valentina Corradi;Paulo C.T. Souza;Helgi I. Ingólfsson

  • The biophysics of peptide models of ion channels.

    Mark S. Sansom

  • Liquid–vapor oscillations of water in hydrophobic nanopores

    Oliver Beckstein;Mark S. P. Sansom

  • Amino acid distributions in integral membrane protein structures

    Martin B. Ulmschneider;Mark S.P. Sansom

  • Acquisition of siderophores in gram-negative bacteria

    José D. Faraldo-Gómez;Mark S. P. Sansom

  • Proline-induced Distortions of Transmembrane Helices

    Frank S. Cordes;Joanne N. Bright;Mark S.P. Sansom

  • Insertion and assembly of membrane proteins via simulation.

    Peter J. Bond;Mark S.P. Sansom

  • Coarse-grained molecular dynamics simulations of membrane proteins and peptides

    Peter J. Bond;John Holyoake;Anthony Ivetac;Syma Khalid

  • Membrane proteins: molecular dynamics simulations.

    Erik Lindahl;Mark S. P. Sansom

  • Structural basis of Smoothened regulation by its extracellular domains

    Eamon F. X. Byrne;Ria Sircar;Paul S. Miller;George Hedger

  • Structure and orientation of the mammalian antibacterial peptide cecropin P1 within phospholipid membranes.

    Ehud Gazit;Israel R. Miller;Israel R. Miller;Phil C. Biggin;Phil C. Biggin;Mark S.P. Sansom;Mark S.P. Sansom

  • Hinges, swivels and switches: the role of prolines in signalling via transmembrane α-helices

    Mark S.P. Sansom;Harel Weinstein

  • PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling

    Hsin-Yung Yen;Kin Kuan Hoi;Idlir Liko;George Hedger

  • Crystal structure of a prokaryotic homologue of the mammalian oligopeptide–proton symporters, PepT1 and PepT2

    Simon Newstead;David Drew;Alexander D Cameron;Vincent L G Postis

  • Simulations of Ion Permeation Through a Potassium Channel: Molecular Dynamics of KcsA in a Phospholipid Bilayer

    Indira H. Shrivastava;Mark S.P. Sansom

  • K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac

    Yin Yao Dong;Ashley C. W. Pike;Alexandra Mackenzie;Alexandra Mackenzie;Conor McClenaghan

  • A Hydrophobic Gating Mechanism for Nanopores

    Oliver Beckstein;Philip C. Biggin;Mark S. P. Sansom

  • Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1

    Tatsuro Shimamura;Tatsuro Shimamura;Simone Weyand;Oliver Beckstein;Nicholas G. Rutherford

  • MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes.

    Phillip J. Stansfeld;Joseph E. Goose;Martin Caffrey;Elisabeth P. Carpenter

  • The influence of geometry, surface character, and flexibility on the permeation of ions and water through biological pores.

    Oliver Beckstein;Mark S P Sansom

  • Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states

    Chitra A. Shintre;Ashley C. W. Pike;Qiuhong Li;Jung-In Kim

  • Hydrophobic gating in ion channels.

    Prafulla Aryal;Mark S.P. Sansom;Stephen J. Tucker

Frequent Co-Authors

Phillip J. Stansfeld
Phillip J. Stansfeld University of Warwick
Stephen J. Tucker
Stephen J. Tucker University of Oxford
Peter J. Bond
Peter J. Bond Agency for Science, Technology and Research
Frances M. Ashcroft
Frances M. Ashcroft University of Oxford
So Iwata
So Iwata Kyoto University
Jonathan W. Essex
Jonathan W. Essex University of Southampton
Alexander D. Cameron
Alexander D. Cameron University of Warwick
Carol V. Robinson
Carol V. Robinson University of Oxford
Christian Siebold
Christian Siebold University of Oxford
Frank Ball
Frank Ball University of Nottingham

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