World's Best Scientists 2026 revealed!
Frances M. Ashcroft

Frances M. Ashcroft

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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
110
Citations
51504
World Ranking
880
National Ranking
88

Medicine

D-Index
112
Citations
52638
World Ranking
5107
National Ranking
502

Frances M. Ashcroft publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Frances M. Ashcroft sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 511 publications — 60th percentile

60% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Frances M. Ashcroft D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Frances M. Ashcroft sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 112 D-Index — 75th percentile

75% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2001 - Member of Academia Europaea
  • 1999 - Fellow of the Royal Society, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Frances M. Ashcroft is affiliated with the University of Oxford in the United Kingdom and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work focuses primarily on molecular biology, surgery, endocrinology, diabetes, metabolism, pathology, forensic medicine, and public health.

The scientist's main research topics include pancreatic function and diabetes, cardiac ischemia and reperfusion, ion channel regulation and function, hyperglycemia and glycemic control in critically ill and hospitalized patients, metabolism related to diabetes and cancer, diabetes management and research, as well as lipid membrane structure and behavior.

Frequent coauthors in their publications are Elizabeth Haythorne, Tanadet Pipatpolkai, Samuel Usher, Phillip J. Stansfeld, and Peter Proks.

Research papers authored or coauthored by Frances M. Ashcroft feature in notable venues such as:

  • Nature Reviews Endocrinology
  • Nature Communications
  • Trends in Endocrinology and Metabolism
  • Proceedings of the National Academy of Sciences
  • Diabetes

Significant recent papers include:

  • New insights into KATP channel gene mutations and neonatal diabetes mellitus, 2020, Nature Reviews Endocrinology
  • Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells, 2022, Nature Communications
  • Glucokinase activity in diabetes: too much of a good thing?, 2022, Trends in Endocrinology and Metabolism
  • Monitoring glycolytic dynamics in single cells using a fluorescent biosensor for fructose 1,6-bisphosphate, 2022, Proceedings of the National Academy of Sciences
  • KATP Channels and the Metabolic Regulation of Insulin Secretion in Health and Disease: The 2022 Banting Medal for Scientific Achievement Award Lecture, 2023, Diabetes

Publication venues where Frances M. Ashcroft has contributed multiple articles include bioRxiv (Cold Spring Harbor Laboratory), Diabetes, Biophysical Journal, Wellcome Open Research, and Nature Reviews Endocrinology.

Ashcroft has been recognized with memberships and fellowships in scientific organizations such as the Royal Society, the Academia Europaea, and the European Molecular Biology Organization (EMBO).

Best Publications

  • The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate–Dependent Nucleic Acid Demethylase

    Thomas Gerken;Christophe A. Girard;Yi-Chun Loraine Tung;Celia J. Webby

  • Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells.

    Frances M. Ashcroft;Donna E. Harrison;Stephen J. H. Ashcroft

  • Activating Mutations in the Gene Encoding the ATP-Sensitive Potassium-Channel Subunit Kir6.2 and Permanent Neonatal Diabetes

    Anna L Gloyn;Ewan R. Pearson;Jennifer F. Antcliff;Peter Proks

  • Electrophysiology of the pancreatic beta-cell.

    Frances M. Ashcroft;Patrik Rorsman

  • Adenosine 5'-triphosphate-sensitive potassium channels

    F M Ashcroft

  • Diabetes Mellitus and the β Cell: The Last Ten Years

    Frances M. Ashcroft;Patrik Rorsman;Patrik Rorsman

  • Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations.

    Ewan R Pearson;Isabelle Flechtner;Pål R Njølstad;Maciej T Malecki

  • Truncation of Kir6.2 produces ATP-sensitive K + channels in the absence of the sulphonylurea receptor

    Stephen J. Tucker;Fiona M. Gribble;Chao Zhao;Stefan Trapp

  • Overexpression of Fto leads to increased food intake and results in obesity.

    Chris Church;Lee Moir;Fiona McMurray;Christophe Girard

  • The essential role of the Walker A motifs of SUR1 in K‐ATP channel activation by Mg‐ADP and diazoxide

    Fiona M. Gribble;Stephen J. Tucker;Frances M. Ashcroft

  • ATP-sensitive potassium channelopathies: focus on insulin secretion.

    Frances M. Ashcroft

  • Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K(ATP) channels.

    F M Gribble;S J Tucker;S Seino;F M Ashcroft

  • Insulin Action in AgRP-Expressing Neurons Is Required for Suppression of Hepatic Glucose Production

    A Christine Konner;Ruth Janoschek;Leona Plum;Sabine Jordan

  • Ion channels and disease

    Frances Ashcroft

  • Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men

    Patrik Rorsman;Patrik Rorsman;Frances M. Ashcroft;Frances M. Ashcroft

  • A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland.

    Timo Otonkoski;Carina Ämmälä;Hanna Huopio;Hanna Huopio;Gilbert J. Cote

  • ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.

    Takashi Miki;Birgit Liss;Kohtaro Minami;Tetsuya Shiuchi

  • Sulfonylurea Stimulation of Insulin Secretion

    Peter Proks;Frank Reimann;Nick Green;Fiona Gribble

  • ATP-sensitive K+ channels and insulin secretion: their role in health and disease.

    F. M. Ashcroft;F. M. Gribble

  • Correlating structure and function in ATP-sensitive K+ channels

    Frances M. Ashcroft;Fiona M. Gribble

Frequent Co-Authors

Fiona M. Gribble
Fiona M. Gribble University of Cambridge
Patrik Rorsman
Patrik Rorsman University of Oxford
Stephen J. Tucker
Stephen J. Tucker University of Oxford
Roger D. Cox
Roger D. Cox Medical Research Council
Frank Reimann
Frank Reimann University of Cambridge
Andrew T. Hattersley
Andrew T. Hattersley University of Exeter
Mark S.P. Sansom
Mark S.P. Sansom University of Oxford
Sian Ellard
Sian Ellard University of Exeter
Phillip J. Stansfeld
Phillip J. Stansfeld University of Warwick
Pål R. Njølstad
Pål R. Njølstad University of Bergen

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