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Lena Eliasson

Lena Eliasson

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
18747
World Ranking
8120
National Ranking
108

Overview

Lena Eliasson is affiliated with Lund University in Sweden and has a research focus primarily in Medicine and Biochemistry, Genetics and Molecular Biology. Their work encompasses a range of studies related to pancreatic function, diabetes, and molecular mechanisms underlying these conditions.

The scientist's research contributions include key topics such as:

  • Pancreatic function and diabetes
  • Diabetes and associated disorders
  • MicroRNA in disease regulation
  • Metabolism, diabetes, and cancer
  • Cancer-related molecular mechanisms research
  • Diabetes treatment and management
  • Diabetes management and research

They have frequently published in journals such as:

  • Diabetes
  • iScience
  • Nature Communications
  • Acta Physiologica
  • bioRxiv (Cold Spring Harbor Laboratory)

Some of the recent papers authored or co-authored by Lena Eliasson include:

  • "A circular RNA generated from an intron of the insulin gene controls insulin secretion" (2020), published in Nature Communications
  • "TIGER: The gene expression regulatory variation landscape of human pancreatic islets" (2021), published in Cell Reports
  • "A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells" (2022), published in Nature Communications
  • "Pancreatic α-cells - The unsung heroes in islet function" (2020), published in Seminars in Cell and Developmental Biology
  • "MicroRNA Networks in Pancreatic Islet Cells: Normal Function and Type 2 Diabetes" (2020), published in Diabetes

Within their collaborative network, Lena Eliasson has frequently worked with co-authors including:

  • Jonathan L.S. Esguerra
  • Alexandros Karagiannopoulos
  • Anna Wendt
  • Elaine Cowan
  • Mototsugu Nagao

Their main fields of study focus extensively on medical and molecular biological aspects of pancreatic and metabolic diseases, with subfields concentrating on surgery, molecular biology, cancer research, genetics, and endocrinology related to diabetes and metabolism.

Best Publications

  • A pancreatic islet-specific microRNA regulates insulin secretion

    Matthew N. Poy;Lena Eliasson;Jan Krutzfeldt;Satoru Kuwajima

  • Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion

    Tasnim Dayeh;Petr Volkov;Sofia Salö;Elin Hall

  • Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

    João Fadista;Petter Vikman;Emilia Ottosson Laakso;Inês Guerra Mollet

  • The Cell Physiology of Biphasic Insulin Secretion

    Patrik Rorsman;Lena Eliasson;Erik Renström;Jesper Gromada

  • Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells

    Erik Renström;Lena Eliasson;Patrik Rorsman

  • Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.

    K Bokvist;Lena Eliasson;C Ammala;Erik Renström

  • Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes

    Anders H. Rosengren;Ramunas Jokubka;Damon Tojjar;Charlotte Granhall

  • Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells.

    Charlotta S. Olofsson;Sven O. Göpel;Sebastian Barg;Juris Galvanovskis

  • Exocytosis elicited by action potentials and voltage‐clamp calcium currents in individual mouse pancreatic B‐cells.

    C Ammälä;L Eliasson;K Bokvist;O Larsson

  • MicroRNA-7a regulates pancreatic β cell function

    Mathieu Latreille;Jean Hausser;Ina Stützer;Quan Zhang

  • GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis.

    Yang Z. De Marinis;Albert Salehi;Caroline E. Ward;Quan Zhang

  • SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells.

    Lena Eliasson;Xiaosong Ma;Erik Renström;Sebastian Barg

  • A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

    Patrick E. MacDonald;Patrick E. MacDonald;Yang Zhang De Marinis;Reshma Ramracheya;S Albert Salehi

  • A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells.

    Sebastian Barg;Lena Eliasson;Erik Renström;Patrik Rorsman

  • Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells.

    Sebastian Barg;Xiaosong Ma;Lena Eliasson;Juris Galvanovskis

  • Rapid ATP-dependent Priming of Secretory Granules Precedes Ca(2+)-induced Exocytosis in Mouse Pancreatic B-cells

    Lena Eliasson;Erik Renström;Wei-Guang Ding;Peter Proks

  • Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes

    Anders H. Rosengren;Matthias Braun;Taman Mahdi;Sofia A. Andersson

  • Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

    Carina Ämmälä;Lena Eliasson;Krister Bokvist;Per Olof Berggren

  • Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets

    Elin Hall;Petr Volkov;Tasnim Dayeh;Jonathan Lou S Esguerra

  • Novel aspects of the molecular mechanisms controlling insulin secretion

    Lena Eliasson;Fernando Abdulkader;Fernando Abdulkader;Matthias Braun;Juris Galvanovskis

Frequent Co-Authors

Patrik Rorsman
Patrik Rorsman University of Oxford
Erik Renström
Erik Renström Lund University
L. M. Kistler
L. M. Kistler University of New Hampshire
Matthew D. McCarthy
Matthew D. McCarthy University of California, Santa Cruz
Rickard Lundin
Rickard Lundin Swedish Institute of Space Physics
H. Rème
H. Rème Paul Sabatier University
B. Klecker
B. Klecker Max Planck Society
A. Korth
A. Korth Max Planck Society
Leif Groop
Leif Groop Lund University
C. W. Carlson
C. W. Carlson University of California, Berkeley

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