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Erik Renström

Erik Renström

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
15026
World Ranking
9645
National Ranking
134

Overview

Erik Renström is affiliated with Lund University in Sweden and focuses primarily on research in biochemistry, genetics, and molecular biology, as well as medicine. Their scholarly output includes a significant number of publications that explore pancreatic function and diabetes, metabolism, and genetics.

Their recent research contributions include work published in high-impact journals, addressing key topics in the regulation of insulin secretion and the molecular mechanisms underlying diabetes. Notable recent papers include:

  • "A circular RNA generated from an intron of the insulin gene controls insulin secretion" (2020, Nature Communications)
  • "A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells" (2022, Nature Communications)
  • "Elevated circulating follistatin associates with an increased risk of type 2 diabetes" (2021, Nature Communications)
  • "Islet Gene View-a tool to facilitate islet research" (2022, Life Science Alliance)
  • "The MafA-target gene PPP1R1A regulates GLP1R-mediated amplification of glucose-stimulated insulin secretion in β-cells" (2021, Metabolism)

Their research fields branch into several subfields including molecular biology, surgery, genetics, cancer research, and endocrinology, diabetes, and metabolism. This multidisciplinary approach supports a research portfolio centered on pancreatic function and diabetes, with additional work focusing on diabetes-associated disorders, metabolism related to diabetes and cancer, epigenetics and DNA methylation, and circular RNAs involved in diseases.

Frequent co-authors collaborating with Erik Renström include:

  • Cheng Luan
  • Lena Eliasson
  • Enming Zhang
  • Mohammad Barghouth
  • Claes B. Wollheim

The scientist's work has been published repeatedly in key venues like Nature Communications, which contains three of their recent papers, as well as Biomedicines, Life Science Alliance, Metabolism, and the Proceedings of the National Academy of Sciences. Their consistent presence in these journals reflects ongoing contributions to the fields of molecular biology and medicine.

Best Publications

  • Insulin granule dynamics in pancreatic beta cells

    Patrik Rorsman;Patrik Rorsman;Erik Renström

  • Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

    João Fadista;Petter Vikman;Emilia Ottosson Laakso;Inês Guerra Mollet

  • The Cell Physiology of Biphasic Insulin Secretion

    Patrik Rorsman;Lena Eliasson;Erik Renström;Jesper Gromada

  • A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.

    Jalal Taneera;Stefan Lang;Amitabh Sharma;Amitabh Sharma;Joao Fadista

  • Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells

    Erik Renström;Lena Eliasson;Patrik Rorsman

  • Redox Control of Exocytosis: Regulatory Role of NADPH, Thioredoxin, and Glutaredoxin

    Rosita Ivarsson;Roel Quintens;Sandra Dejonghe;Katsura Tsukamoto

  • Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.

    K Bokvist;Lena Eliasson;C Ammala;Erik Renström

  • The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery

    Ofer Wiser;Michael Trus;Ana Hernández;Erik Renström

  • Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes

    Anders H. Rosengren;Ramunas Jokubka;Damon Tojjar;Charlotte Granhall

  • Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes.

    Beatrice T. Yang;Tasnim A. Dayeh;Petr A. Volkov;Clare L. Kirkpatrick

  • Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice.

    Verena Schulla;Erik Renström;Robert Feil;Susanne Feil

  • GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis.

    Yang Z. De Marinis;Albert Salehi;Caroline E. Ward;Quan Zhang

  • SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells.

    Lena Eliasson;Xiaosong Ma;Erik Renström;Sebastian Barg

  • A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells.

    Sebastian Barg;Lena Eliasson;Erik Renström;Patrik Rorsman

  • Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells.

    Sebastian Barg;Xiaosong Ma;Lena Eliasson;Juris Galvanovskis

  • Neurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin.

    Erik Renström;Wei-Guang Ding;Krister Bokvist;Patrik Rorsman

  • Rapid ATP-dependent Priming of Secretory Granules Precedes Ca(2+)-induced Exocytosis in Mouse Pancreatic B-cells

    Lena Eliasson;Erik Renström;Wei-Guang Ding;Peter Proks

  • Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes

    Anders H. Rosengren;Matthias Braun;Taman Mahdi;Sofia A. Andersson

  • CaV2.3 calcium channels control second-phase insulin release.

    Xingjun Jing;Dai-Qing Li;Charlotta S. Olofsson;Albert Salehi

  • Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca 2+ channels.

    Martina J. Sinnegger-Brauns;Alfred Hetzenauer;Irene G. Huber;Erik Renström

Frequent Co-Authors

Patrik Rorsman
Patrik Rorsman University of Oxford
Lena Eliasson
Lena Eliasson Lund University
Leif Groop
Leif Groop Lund University
Anna M. Blom
Anna M. Blom Lund University
Claes B. Wollheim
Claes B. Wollheim University of Geneva
Valeriya Lyssenko
Valeriya Lyssenko University of Bergen
Hindrik Mulder
Hindrik Mulder Lund University
Gunilla T. Westermark
Gunilla T. Westermark Uppsala University
Olle Korsgren
Olle Korsgren Uppsala University
Tiinamaija Tuomi
Tiinamaija Tuomi University of Helsinki

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