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Per-Olof Berggren

Per-Olof Berggren

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Biology and Biochemistry
Sweden
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
105
Citations
33445
World Ranking
1221
National Ranking
22

Medicine

D-Index
105
Citations
33481
World Ranking
6852
National Ranking
141

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award
  • 2017 - Fellow of the American Academy of Arts and Sciences
  • 2016 - Member of the National Academy of Medicine (NAM)
  • 2009 - Member of Academia Europaea

Overview

Per-Olof Berggren is affiliated with the Karolinska Institute in Sweden. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, contributing to 108 and 90 publications respectively. Within these broad domains, Berggren's work concentrates on several subfields, including Surgery, Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, and Physiology.

The researcher's work covers various topics with a strong focus on diabetes and pancreatic function, reflecting in the main topics of their publications. These include pancreatic function and diabetes, diabetes and associated disorders, diabetes management and research, metabolism related to diabetes and cancer, adipose tissue and metabolism, RNA interference and gene delivery, and endoplasmic reticulum stress and disease.

Some of the recent papers authored in collaboration with other scientists illustrate the scope of their research interests and contributions:

  • Alpha cell regulation of beta cell function, 2020, Diabetologia
  • Biodegradable and Antioxidant DNA Hydrogel as a Cytokine Delivery System for Diabetic Wound Healing, 2022, Advanced Healthcare Materials
  • HIF-1α inhibitor PX-478 preserves pancreatic β cell function in diabetes, 2022, Science Translational Medicine
  • A DNA Nanoraft-Based Cytokine Delivery Platform for Alleviation of Acute Kidney Injury, 2021, ACS Nano
  • Physically Cross-Linked DNA Hydrogel-Based Sustained Cytokine Delivery for In Situ Diabetic Alveolar Bone Rebuilding, 2022, ACS Applied Materials & Interfaces

Frequent coauthors collaborating with Berggren include:

  • Ingo B. Leibiger (18 collaborations)
  • Noah Moruzzi (15 collaborations)
  • Barbara Leibiger (15 collaborations)
  • Xiaofeng Zheng (13 collaborations)
  • Ismael Valladolid-Acebes (12 collaborations)

Berggren's research has been published repeatedly in several scientific venues, with frequent publications in the following journals:

  • International Journal of Molecular Sciences (5 publications)
  • Cell Transplantation (5 publications)
  • Nature Communications (3 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (3 publications)
  • Diabetologia (2 publications)

Over the course of their career, Berggren has received recognition including election as a Fellow of the American Academy of Arts and Sciences in 2017, membership in the National Academy of Medicine in 2016, and membership of Academia Europaea since 2009.

Best Publications

  • The unique cytoarchitecture of human pancreatic islets has implications for islet cell function

    Over Cabrera;Dora M. Berman;Norma S. Kenyon;Camillo Ricordi

  • Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels.

    Patrik Rorsman;Per Olof Berggren;Krister Bokvist;Hans Ericson

  • Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

    Ioulia B. Efanova;Sergei V. Zaitsev;Sergei V. Zaitsev;Boris Zhivotovsky;Martin Köhler

  • Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes

    José P. Silva;Martin Köhler;Caroline Graff;Anders Oldfors

  • Exocytosis of Insulin Promotes Insulin Gene Transcription via the Insulin Receptor/PI-3 Kinase/p70 s6 Kinase and CaM Kinase Pathways

    Ingo B. Leibiger;Barbara Leibiger;Tilo Moede;Per Olof Berggren

  • Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic β cells

    Barbara Leibiger;Ingo B. Leibiger;Tilo Moede;Sabine Kemper

  • Innervation Patterns of Autonomic Axons in the Human Endocrine Pancreas

    Rayner Rodriguez-Diaz;Midhat H. Abdulreda;Alexander L. Formoso;Itai Gans

  • Adipsin is an Adipokine that Improves β Cell Function in Diabetes

    James C. Lo;James C. Lo;Sanda Ljubicic;Barbara Leibiger;Matthias Kern

  • The Role of Voltage-Gated Calcium Channels in Pancreatic β-Cell Physiology and Pathophysiology

    Shao Nian Yang;Per Olof Berggren

  • Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans

    Rayner Rodriguez-Diaz;Rayner Rodriguez-Diaz;Robin Dando;M. Caroline Jacques-Silva;Alberto Fachado

  • Noninvasive in vivo imaging of pancreatic islet cell biology

    Stephan Speier;Daniel Nyqvist;Over Cabrera;Jia Yu

  • Dopamine-induced Endocytosis of Na+,K+-ATPase Is Initiated by Phosphorylation of Ser-18 in the Rat α Subunit and Is Responsible for the Decreased Activity in Epithelial Cells

    Alexander V. Chibalin;Goichi Ogimoto;Carlos H. Pedemonte;Thomas A. Pressley

  • SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells.

    Lena Eliasson;Xiaosong Ma;Erik Renström;Sebastian Barg

  • Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose.

    Chiyo Shiota;Olof Larsson;Kathy D. Shelton;Masakazu Shiota

  • Insulin Signaling in the Pancreatic β-Cell

    Ingo B. Leibiger;Barbara Leibiger;Per Olof Berggren

  • Increased activity of L-type Ca2+ channels exposed to serum from patients with type I diabetes

    Lisa Juntti-Berggren;Olof Larsson;Patrik Rorsman;Carina Ämmälä

  • Identification of synaptic proteins and their isoform mRNAs in compartments of pancreatic endocrine cells.

    Gunilla Jacobsson;Andrew J. Bean;Richard H. Scheller;Lisa Juntti-Berggren

  • Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action

    F. Thomas Wunderlich;Peter Ströhle;A. Christine Könner;Sabine Gruber

  • Acute Stimulation with Long Chain Acyl-CoA Enhances Exocytosis in Insulin-secreting Cells (HIT T-15 and NMRI β-Cells)

    Jude T. Deeney;Jude T. Deeney;Jesper Gromada;Marianne Høy;Hervør L. Olsen

  • Glutamate Is a Positive Autocrine Signal for Glucagon Release

    Over Cabrera;Over Cabrera;M. Caroline Jacques-Silva;Stephan Speier;Shao Nian Yang

Frequent Co-Authors

Patrik Rorsman
Patrik Rorsman University of Oxford
Suad Efendic
Suad Efendic Karolinska Institute
Camillo Ricordi
Camillo Ricordi University of Miami
Sung Ho Ryu
Sung Ho Ryu Pohang University of Science and Technology
Barbara E. Corkey
Barbara E. Corkey Boston University
Björn Meister
Björn Meister Karolinska Institute
Michael Welsh
Michael Welsh Uppsala University
Peter R. Flatt
Peter R. Flatt University of Ulster
Thomas Mandrup-Poulsen
Thomas Mandrup-Poulsen University of Copenhagen
Hans Jörnvall
Hans Jörnvall Karolinska Institute

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