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Medicine

D-Index
87
Citations
28473
World Ranking
13626
National Ranking
6925

Overview

Rohit N. Kulkarni is affiliated with Harvard Medical School in the United States. Their research primarily focuses on pancreatic function and diabetes, with contributions to topics such as ionosphere and magnetosphere dynamics, geophysics and gravity measurements, methane hydrates and related phenomena, solar and space plasma dynamics, astrophysics and cosmic phenomena, and seismic waves and analysis.

Frequently publishing in a range of scientific venues, Kulkarni has numerous papers in prestigious journals and platforms. The most common publication venues include:

  • OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
  • Diabetes
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the Endocrine Society
  • Nature Communications

Some recent papers authored or co-authored by Kulkarni illustrate the scope and focus of their research. These include:

  • Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention, 2020, Cell Metabolism
  • Monogenic diabetes, 2023, Nature Reviews Disease Primers
  • Abnormal exocrine-endocrine cell cross-talk promotes β-cell dysfunction and loss in MODY8, 2022, Nature Metabolism
  • A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism, 2020, Nature Communications
  • Maternal and paternal exercise regulate offspring metabolic health and beta cell phenotype, 2020, BMJ Open Diabetes Research & Care

Throughout their career, Kulkarni has collaborated with various researchers with significant co-authorship counts, including:

  • Weijun Qian
  • Jon Jacobs
  • Tujin Shi
  • Christina Stevenson
  • Zhangyang Xu

Their academic work spans a variety of fields of study, predominantly within physical sciences and biological sciences intersections. Key main fields of study are:

  • Physics and Astronomy
  • Earth and Planetary Sciences

Within these fields, Kulkarni has contributed to notable subfields such as:

  • Astronomy and Astrophysics
  • Oceanography
  • Environmental Chemistry
  • Nuclear and High Energy Physics
  • Molecular Biology

Best Publications

  • Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction

    M.Dodson Michael;Rohit N. Kulkarni;Catherine Postic;Steven F. Previs

  • Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes

    R N Kulkarni;J C Brüning;J N Winnay;C Postic

  • New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

    Yu Hua Tseng;Efi Kokkotou;Tim J. Schulz;Tian Lian Huang

  • TRB3: A tribbles Homolog That Inhibits Akt/PKB Activation by Insulin in Liver

    Keyong Du;Stephan Herzig;Rohit N. Kulkarni;Marc Montminy

  • Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

    David S. Ludwig;Nicholas A. Tritos;Jason W. Mastaitis;Rohit Kulkarni

  • cAMP promotes pancreatic β-cell survival via CREB-mediated induction of IRS2

    Ulupi S. Jhala;Gianluca Canettieri;Robert A. Screaton;Rohit N. Kulkarni

  • PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3

    Seung Hoi Koo;Hiroaki Satoh;Stephan Herzig;Chih Hao Lee

  • Loss of ARNT/HIF1β Mediates Altered Gene Expression and Pancreatic-Islet Dysfunction in Human Type 2 Diabetes

    Jenny E. Gunton;Rohit N. Kulkarni;Sun Hee Yim;Terumasa Okada

  • beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.

    R N Kulkarni;M Holzenberger;D Q Shih;U Ozcan

  • Abnormal glucose homeostasis in skeletal muscle–specific PGC-1α knockout mice reveals skeletal muscle–pancreatic β cell crosstalk

    Christoph Handschin;Cheol Soo Choi;Sherry Chin;Sheene Kim

  • Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance.

    Terumasa Okada;Chong Wee Liew;Jiang Hu;Charlotte Hinault

  • Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic β cells

    Barbara Leibiger;Ingo B. Leibiger;Tilo Moede;Sabine Kemper

  • Insulin Signaling in α Cells Modulates Glucagon Secretion In Vivo

    Dan Kawamori;Amarnath J. Kurpad;Jiang Hu;Chong Wee Liew

  • TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.

    Ling Qi;Jose E. Heredia;Judith Y. Altarejos;Robert Screaton

  • Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice.

    Rohit N. Kulkarni;Zhi Li Wang;Ren Ming Wang;James D. Hurley

  • Upregulation of insulin receptor substrate-2 in pancreatic β cells prevents diabetes

    Anita M. Hennige;Deborah J. Burks;Umut Ozcan;Rohit N. Kulkarni

  • Altered function of insulin receptor substrate-1–deficient mouse islets and cultured β-cell lines

    Rohit N. Kulkarni;Jonathon N. Winnay;Molly Daniels;Jens C. Brüning

  • Total insulin and IGF-I resistance in pancreatic β cells causes overt diabetes

    Kohjiro Ueki;Terumasa Okada;Jiang Hu;Chong Wee Liew

  • Disruption of leptin receptor expression in the pancreas directly affects β cell growth and function in mice

    Tomoaki Morioka;Esra Asilmaz;Jiang Hu;John F. Dishinger

  • PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance

    Rohit N. Kulkarni;Ulupi S. Jhala;Jonathon N. Winnay;Stan Krajewski

Frequent Co-Authors

C. Ronald Kahn
C. Ronald Kahn Harvard University
Wei-Jun Qian
Wei-Jun Qian Pacific Northwest National Laboratory
Pål R. Njølstad
Pål R. Njølstad University of Bergen
Anders Molven
Anders Molven University of Bergen
Richard D. Smith
Richard D. Smith Pacific Northwest National Laboratory
Amy J. Wagers
Amy J. Wagers Harvard University
Robert T. Kennedy
Robert T. Kennedy University of Michigan–Ann Arbor
Marina A. Gritsenko
Marina A. Gritsenko Pacific Northwest National Laboratory
Yu-Hua Tseng
Yu-Hua Tseng Harvard University
Kohjiro Ueki
Kohjiro Ueki National Center For Global Health and Medicine

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