D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 80 Citations 23,743 285 World Ranking 11867 National Ranking 6209

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Enzyme

His main research concerns Internal medicine, Endocrinology, Insulin, Insulin receptor and Insulin resistance. His study in Insulin oscillation, Islet, Glucose homeostasis, IRS2 and Pancreatic islets is carried out as part of his Internal medicine studies. His studies in Endocrinology integrate themes in fields like Receptor, Protein kinase B and Cell biology.

His research in the fields of Beta cell overlaps with other disciplines such as Calcium metabolism. His study in Insulin receptor is interdisciplinary in nature, drawing from both Knockout mouse and Hyperinsulinemia. In his research, TRIB3, Incretin and Diabetes mellitus genetics is intimately related to Glucose uptake, which falls under the overarching field of Insulin resistance.

His most cited work include:

  • Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction (1050 citations)
  • Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes (998 citations)
  • New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure (843 citations)

What are the main themes of his work throughout his whole career to date?

Rohit N. Kulkarni focuses on Internal medicine, Endocrinology, Insulin, Insulin resistance and Cell biology. All of his Endocrinology and Insulin receptor, Glucose homeostasis, Islet, Diabetes mellitus and Insulin oscillation investigations are sub-components of the entire Endocrinology study. His work carried out in the field of Insulin receptor brings together such families of science as PI3K/AKT/mTOR pathway, Downregulation and upregulation and Glucagon secretion.

The various areas that Rohit N. Kulkarni examines in his Insulin study include Adipose tissue, Protein kinase B, Knockout mouse and Carbohydrate metabolism. The study incorporates disciplines such as Epigenetics and Type 2 diabetes in addition to Insulin resistance. His Cell biology research incorporates themes from Cell, Receptor and Induced pluripotent stem cell.

He most often published in these fields:

  • Internal medicine (63.73%)
  • Endocrinology (60.46%)
  • Insulin (44.44%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (29.08%)
  • Insulin resistance (32.68%)
  • Internal medicine (63.73%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cell biology, Insulin resistance, Internal medicine, Endocrinology and Insulin. His Cell biology research is multidisciplinary, incorporating elements of Cell, Proteomics, Induced pluripotent stem cell, Translation and Islet. He interconnects Gene expression, FOXO1, Gene silencing, Epigenetics and Type 2 diabetes in the investigation of issues within Insulin resistance.

His Insulin receptor, Steatosis and Thiamine study in the realm of Internal medicine interacts with subjects such as Nonalcoholic fatty liver disease. His work in the fields of Diabetes mellitus genetics overlaps with other areas such as Solute carrier family. He has included themes like Diabetes mellitus, Messenger RNA, Transdifferentiation and Pharmacology in his Insulin study.

Between 2018 and 2021, his most popular works were:

  • m 6 A mRNA Methylation Regulates Human β-Cell Biology in Physiological States and in Type 2 Diabetes (42 citations)
  • RADAR: differential analysis of MeRIP-seq data with a random effect model (34 citations)
  • β-Cell Fate in Human Insulin Resistance and Type 2 Diabetes: A Perspective on Islet Plasticity (31 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His scientific interests lie mostly in Insulin resistance, Islet, Internal medicine, Endocrinology and Cell. His Insulin resistance study results in a more complete grasp of Insulin. He has researched Islet in several fields, including Inflammation, Secretion, Cancer research and Cytokine.

His study in the field of Steatosis, Metabolic syndrome and Insulin receptor also crosses realms of Nonalcoholic fatty liver disease. His Endocrinology research incorporates elements of Downregulation and upregulation and Epigenetics. Rohit N. Kulkarni combines subjects such as MAPK/ERK pathway, Cell growth, Pancreas and Cell biology with his study of Cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction

M.Dodson Michael;Rohit N. Kulkarni;Catherine Postic;Steven F. Previs.
Molecular Cell (2000)

1478 Citations

Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes

R N Kulkarni;J C Brüning;J N Winnay;C Postic.
Cell (1999)

1424 Citations

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

Yu Hua Tseng;Efi Kokkotou;Tim J. Schulz;Tian Lian Huang.
Nature (2008)

1195 Citations

TRB3: A tribbles Homolog That Inhibits Akt/PKB Activation by Insulin in Liver

Keyong Du;Stephan Herzig;Rohit N. Kulkarni;Marc Montminy.
Science (2003)

1162 Citations

Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance

David S. Ludwig;Nicholas A. Tritos;Jason W. Mastaitis;Rohit Kulkarni.
Journal of Clinical Investigation (2001)

710 Citations

cAMP promotes pancreatic β-cell survival via CREB-mediated induction of IRS2

Ulupi S. Jhala;Gianluca Canettieri;Robert A. Screaton;Rohit N. Kulkarni.
Genes & Development (2003)

657 Citations

PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3

Seung Hoi Koo;Hiroaki Satoh;Stephan Herzig;Chih Hao Lee.
Nature Medicine (2004)

646 Citations

Loss of ARNT/HIF1β Mediates Altered Gene Expression and Pancreatic-Islet Dysfunction in Human Type 2 Diabetes

Jenny E. Gunton;Rohit N. Kulkarni;Sun Hee Yim;Terumasa Okada.
Cell (2005)

554 Citations

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.

R N Kulkarni;M Holzenberger;D Q Shih;U Ozcan.
Nature Genetics (2002)

424 Citations

Abnormal glucose homeostasis in skeletal muscle–specific PGC-1α knockout mice reveals skeletal muscle–pancreatic β cell crosstalk

Christoph Handschin;Cheol Soo Choi;Sherry Chin;Sheene Kim.
Journal of Clinical Investigation (2007)

397 Citations

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