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Christoph Handschin

Christoph Handschin

University of Basel
Switzerland

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
26849
World Ranking
11670
National Ranking
209

Christoph Handschin publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Christoph Handschin sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 162 publications — 32nd percentile

32% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Christoph Handschin D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Christoph Handschin sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 60 D-Index — 41st percentile

41% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Christoph Handschin is affiliated with the University of Basel in Switzerland and has an extensive research background primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work encompasses molecular biology, physiology, aging, rehabilitation, and genetics, reflecting a broad focus within the life sciences.

The scientist's research covers several main topics, including adipose tissue and metabolism, muscle physiology and disorders, genetics, aging, and longevity in model organisms, exercise and physiological responses, mitochondrial function and pathology, circadian rhythm and melatonin, and genetics and physical performance.

Christoph Handschin has published numerous papers in reputable venues. Some recent publications include:

  • The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia, 2020, published in Nature Communications
  • The molecular athlete: exercise physiology from mechanisms to medals, 2023, published in Physiological Reviews
  • Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle, 2022, published in Nature Communications
  • The Role of the Skeletal Muscle Secretome in Mediating Endurance and Resistance Training Adaptations, 2021, published in Frontiers in Physiology
  • Molecular control of endurance training adaptation in male mouse skeletal muscle, 2023, published in Nature Metabolism

Frequent publication venues for Handschin include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, The Journal of Physiology, Molecular Metabolism, and Physiological Reviews. These venues reflect a focus on both molecular and physiological aspects of biomedical research.

The scientist has collaborated frequently with several co-authors, notably Regula Furrer, Danilo Ritz, Julien Delezie, Aurel B. Leuchtmann, and Bettina Karrer-Cardel, indicating a collaborative research environment.

Best Publications

  • AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

    Sibylle Jäger;Christoph Handschin;Julie St-Pierre;Bruce M Spiegelman

  • Metabolic control through the PGC-1 family of transcription coactivators.

    Jiandie D. Lin;Christoph Handschin;Bruce M Spiegelman

  • Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

    Julie St-Pierre;Stavit Drori;Marc Uldry;Jessica M. Silvaggi

  • The role of exercise and PGC1α in inflammation and chronic disease

    Christoph Handschin;Bruce M. Spiegelman

  • Peroxisome Proliferator-Activated Receptor γ Coactivator 1 Coactivators, Energy Homeostasis, and Metabolism

    Christophe Handschin;Bruce M Spiegelman

  • PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

    Marco Sandri;Jiandie Lin;Christoph Handschin;Wenli Yang

  • An autoregulatory loop controls peroxisome proliferator-activated receptor γ coactivator 1α expression in muscle

    Christoph Handschin;James Rhee;Jiandie Lin;Paul T. Tarr

  • Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

    Vamsi K. Mootha;Christoph Handschin;Dan Arlow;Xiaohui Xie

  • Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle

    Zoltan Arany;Huamei He;Jiandie Lin;Kirsten Hoyer

  • Hyperlipidemic Effects of Dietary Saturated Fats Mediated through PGC-1β Coactivation of SREBP

    Jiandie Lin;Ruojing Yang;Paul T. Tarr;Pei Hsuan Wu

  • Skeletal Muscle Fiber-type Switching, Exercise Intolerance, and Myopathy in PGC-1α Muscle-specific Knock-out Animals

    Christoph Handschin;Sherry Chin;Ping Li;Fenfen Liu

  • Induction of Drug Metabolism: The Role of Nuclear Receptors

    Christoph Handschin;Urs A. Meyer

  • Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise

    Svenia Schnyder;Christoph Handschin

  • Nutritional Regulation of Hepatic Heme Biosynthesis and Porphyria through PGC-1α

    Christoph Handschin;Jiandie Lin;James Rhee;Anne Kathrin Peyer

  • Abnormal glucose homeostasis in skeletal muscle–specific PGC-1α knockout mice reveals skeletal muscle–pancreatic β cell crosstalk

    Christoph Handschin;Cheol Soo Choi;Sherry Chin;Sheene Kim

  • PGC-1α regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy

    Christoph Handschin;Yvonne M. Kobayashi;Sherry Chin;Patrick Seale

  • Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α: modulation by p38 MAPK

    Melina Fan;James Rhee;Julie St-Pierre;Christoph Handschin

  • Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1α transcription and mitochondrial biogenesis in muscle cells

    Zhidan Wu;Xueming Huang;Yajun Feng;Christoph Handschin

  • Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

    Cheol Soo Choi;Douglas E. Befroy;Roberto Codella;Sheene Kim

  • Endocrine Crosstalk Between Skeletal Muscle and the Brain.

    Julien Delezie;Christoph Handschin

Frequent Co-Authors

Bruce M. Spiegelman
Bruce M. Spiegelman Harvard University
Jiandie D. Lin
Jiandie D. Lin University of Michigan–Ann Arbor
Francesco Zorzato
Francesco Zorzato University of Ferrara
Erik van Nimwegen
Erik van Nimwegen University of Basel
Alexander Schmidt
Alexander Schmidt University of Basel
Julie St-Pierre
Julie St-Pierre McGill University
Markus A. Rüegg
Markus A. Rüegg University of Basel
Susan Treves
Susan Treves University Hospital of Basel
Vamsi K. Mootha
Vamsi K. Mootha Harvard Medical School
Christoph Hess
Christoph Hess University of Cambridge

External Links

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