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Biology and Biochemistry

D-Index
67
Citations
52377
World Ranking
8009
National Ranking
3626

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jiandie D. Lin is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several specialized subfields including Molecular Biology, Epidemiology, Physiology, Immunology, and Surgery.

The scientist's main research topics encompass:

  • Adipose Tissue and Metabolism
  • Liver Disease Diagnosis and Treatment
  • Adipokines, Inflammation, and Metabolic Diseases
  • Pancreatic function and diabetes
  • Regulation of Appetite and Obesity
  • Immune cells in cancer
  • Lipid metabolism and disorders

Jiandie D. Lin has contributed to several publication venues, with frequent publications in:

  • Hepatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Metabolism
  • Cell Reports
  • Journal of Clinical Investigation

Recent significant papers include:

  • "Neuregulin 4 suppresses NASH-HCC development by restraining tumor-prone liver microenvironment," 2022, Cell Metabolism
  • "Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis," 2020, Cell Reports
  • "Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling," 2020, Journal of Clinical Investigation
  • "The obesity-induced adipokine sST2 exacerbates adipose T reg and ILC2 depletion and promotes insulin resistance," 2020, Science Advances
  • "DT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates," 2023, Cell Metabolism

Frequent coauthors in their research include Zhimin Chen, Tongyu Liu, Henry Kuang, Linkang Zhou, and Ziyi Meng.

Jiandie D. Lin was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2018.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

    Jiandie Lin;Hai Wu;Paul T. Tarr;Chen Yu Zhang

  • TEAD mediates YAP-dependent gene induction and growth control

    Bin Zhao;Xin Ye;Jindan Yu;Li Li;Li Li

  • Metabolic control through the PGC-1 family of transcription coactivators.

    Jiandie D. Lin;Christoph Handschin;Bruce M Spiegelman

  • Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

    Julie St-Pierre;Stavit Drori;Marc Uldry;Jessica M. Silvaggi

  • Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway

    Christiane D. Wrann;James P. White;John Salogiannnis;Dina Laznik-Bogoslavski

  • Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice

    Jiandie Lin;Pei Hsuan Wu;Paul T. Tarr;Katrin S. Lindenberg

  • PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

    Marco Sandri;Jiandie Lin;Christoph Handschin;Wenli Yang

  • Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPARγ Coactivator-1

    Pere Puigserver;James Rhee;Jiandie Lin;Zhidan Wu

  • An autoregulatory loop controls peroxisome proliferator-activated receptor γ coactivator 1α expression in muscle

    Christoph Handschin;James Rhee;Jiandie Lin;Paul T. Tarr

  • Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle

    Zoltan Arany;Huamei He;Jiandie Lin;Kirsten Hoyer

  • Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation

    Marc Uldry;Wenli Yang;Julie St-Pierre;Jiandie Lin

  • Hyperlipidemic Effects of Dietary Saturated Fats Mediated through PGC-1β Coactivation of SREBP

    Jiandie Lin;Ruojing Yang;Paul T. Tarr;Pei Hsuan Wu

  • Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism

    Chang Liu;Siming Li;Tiecheng Liu;Jimo Borjigin

  • Bioenergetic Analysis of Peroxisome Proliferator-activated Receptor γ Coactivators 1α and 1β (PGC-1α and PGC-1β) in Muscle Cells

    Julie St-Pierre;Jiandie Lin;Stefan Krauss;Paul T. Tarr

  • Peroxisome Proliferator-activated Receptor γ Coactivator 1β (PGC-1β), A Novel PGC-1-related Transcription Coactivator Associated with Host Cell Factor

    Jiandie Lin;Pere Puigserver;Jerry Donovan;Paul Tarr

  • Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis.

    Xuelian Xiong;Xuelian Xiong;Henry Kuang;Sahar Ansari;Tongyu Liu

  • Functions of autophagy in normal and diseased liver

    Mark J. Czaja;Wen Xing Ding;Terrence M. Donohue;Scott L. Friedman

  • Muscle-specific expression of PPARγ coactivator-1α improves exercise performance and increases peak oxygen uptake

    Jennifer Ann Calvo;Thomas G. Daniels;Xiaomei Wang;Angelika C. Paul

Frequent Co-Authors

Bruce M. Spiegelman
Bruce M. Spiegelman Harvard University
Christoph Handschin
Christoph Handschin University of Basel
Daniel I. H. Linzer
Daniel I. H. Linzer Research Corporation for Science Advancement
Y. Eugene Chen
Y. Eugene Chen University of Michigan–Ann Arbor
Paul L. Carson
Paul L. Carson University of Michigan–Ann Arbor
Jifeng Zhang
Jifeng Zhang University of Michigan–Ann Arbor
Pere Puigserver
Pere Puigserver Harvard University
Philippe Pierre
Philippe Pierre Aix-Marseille University
Sergio Lavandero
Sergio Lavandero University of Chile
Bradford B. Lowell
Bradford B. Lowell Beth Israel Deaconess Medical Center

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