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Biology and Biochemistry

D-Index
68
Citations
15268
World Ranking
7856
National Ranking
3569

Overview

Jifeng Zhang is affiliated with the University of Michigan-Ann Arbor in the United States, contributing to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans multiple subfields, including Molecular Biology, Pulmonary and Respiratory Medicine, Surgery, Genetics, and Immunology.

Their work notably covers a range of topics with a focus on cardiovascular and metabolic diseases. Key research areas include:

  • Aortic aneurysm repair treatments
  • CRISPR and Genetic Engineering
  • Aortic Disease and Treatment Approaches
  • Connective tissue disorders research
  • Kruppel-like factors research
  • Liver Disease Diagnosis and Treatment
  • Atherosclerosis and Cardiovascular Diseases

Jifeng Zhang has published extensively in several prominent scientific journals. Frequent publication venues include:

  • Arteriosclerosis Thrombosis and Vascular Biology
  • Circulation
  • JCI Insight
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cells

Some of the recent papers published by Zhang are:

  • "Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome" (2020, Science Translational Medicine)
  • "Single-cell RNA sequencing reveals the cellular heterogeneity of aneurysmal infrarenal abdominal aorta" (2020, Cardiovascular Research)
  • "Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection" (2021, European Heart Journal)
  • "Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB" (2020, Circulation)
  • "Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease" (2020, Nature Communications)

Zhang frequently collaborates with several coauthors, including:

  • Y. Eugene Chen
  • Guizhen Zhao
  • Yanhong Guo
  • Dongshan Yang
  • Lin Chang

Best Publications

  • Nitrolinoleic acid: An endogenous peroxisome proliferator-activated receptor γ ligand

    Francisco J. Schopfer;Yiming Lin;Paul R. S. Baker;Taixing Cui

  • RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency.

    Jun Song;Dongshan Yang;Jie Xu;Tianqing Zhu

  • Nitrated Fatty Acids: Endogenous Anti-inflammatory Signaling Mediators

    Taixing Cui;Francisco J. Schopfer;Jifeng Zhang;Kai Chen

  • Loss of Perivascular Adipose Tissue on Peroxisome Proliferator–Activated Receptor-γ Deletion in Smooth Muscle Cells Impairs Intravascular Thermoregulation and Enhances Atherosclerosis

    Lin Chang;Luis Villacorta;Rongxia Li;Milton Hamblin

  • miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia

    Ke Jie Yin;Zhen Deng;Huarong Huang;Milton Hamblin

  • Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine.

    Jianglin Fan;Shuji Kitajima;Teruo Watanabe;Jie Xu

  • Perivascular Adipose Tissue in Vascular Function and Disease: A Review of Current Research and Animal Models

    Nicholas K. Brown;Zhou Zhou;Jifeng Zhang;Rong Zeng

  • Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

    Oddgeir L Holmen;He-Ming Zhang;Yanbo Fan;Daniel H. Hovelson

  • PPARs and the cardiovascular system.

    Milton Hamblin;Lin Chang;Yanbo Fan;Jifeng Zhang

  • Peroxisome Proliferator-activated Receptor γ Inhibits Transforming Growth Factor β-induced Connective Tissue Growth Factor Expression in Human Aortic Smooth Muscle Cells by Interfering with Smad3

    Mingui Fu;Jifeng Zhang;Xiaojun Zhu;David E. Myles

  • Molecular recognition of nitrated fatty acids by PPAR gamma.

    Yong Li;Yong Li;Jifeng Zhang;Francisco J Schopfer;Dariusz Martynowski

  • Peroxisome proliferator-activated receptor delta regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury.

    Ke Jie Yin;Zhen Deng;Zhen Deng;Milton Hamblin;Yi Xiang

  • Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning

    Dongshan Yang;Huaqiang Yang;Wei Li;Bentian Zhao

  • Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome

    Oren Rom;Yuhao Liu;Zhipeng Liu;Ying Zhao

  • Covalent Peroxisome Proliferator-activated Receptor γ Adduction by Nitro-fatty Acids SELECTIVE LIGAND ACTIVITY AND ANTI-DIABETIC SIGNALING ACTIONS

    Francisco J. Schopfer;Marsha P. Cole;Alison L. Groeger;Chen Shan Chen

  • Effective gene targeting in rabbits using RNA-guided Cas9 nucleases

    Dongshan Yang;Jie Xu;Tianqing Zhu;Jianglin Fan

  • MicroRNA-1 regulates smooth muscle cell differentiation by repressing Kruppel-like factor 4.

    Changqing Xie;Huarong Huang;Xuan Sun;Yanhong Guo

  • Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated Receptors

    Raghu R. V. Malapaka;Sok Kean Khoo;Jifeng Zhang;Jang Hyun Choi

  • Nitro-linoleic acid inhibits vascular smooth muscle cell proliferation via the Keap1/Nrf2 signaling pathway

    Luis Villacorta;Jifeng Zhang;Minerva T. Garcia-Barrio;Xi Lin Chen

  • Macrophage polarization in atherosclerosis.

    Sai Yang;Hou-Qin Yuan;Ya-Meng Hao;Zhong Ren

Frequent Co-Authors

Y. Eugene Chen
Y. Eugene Chen University of Michigan–Ann Arbor
Jianglin Fan
Jianglin Fan University of Yamanashi
Bruce A. Freeman
Bruce A. Freeman University of Pittsburgh
Francisco J. Schopfer
Francisco J. Schopfer University of Pittsburgh
Cristen J. Willer
Cristen J. Willer University of Michigan–Ann Arbor
Kristian Hveem
Kristian Hveem Norwegian University of Science and Technology
Jiandie D. Lin
Jiandie D. Lin University of Michigan–Ann Arbor
Yixue Li
Yixue Li Chinese Academy of Sciences
Gonçalo R. Abecasis
Gonçalo R. Abecasis University of Michigan–Ann Arbor
Peter X. Ma
Peter X. Ma University of Michigan–Ann Arbor

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