World's Best Scientists 2026 revealed!
Yoshimi Takai

Yoshimi Takai

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
152
Citations
94185
World Ranking
165
National Ranking
4

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2022 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Yoshimi Takai is affiliated with Kobe University in Japan, where their research encompasses various aspects of biochemistry, genetics, and molecular biology, with a significant focus on neuroscience. Their work spans multiple subfields including molecular biology, cellular and molecular neuroscience, cell biology, neurology, and immunology.

The scientist's research topics are diverse, including neuroscience and neuropharmacology, Wnt/β-catenin signaling in development and cancer, retinal development and disorders, galectins and cancer biology, barrier structure and function studies, neurogenesis and neuroplasticity mechanisms, as well as cellular transport and secretion.

Their recent published papers include:

  • "Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors" (2020), published in Neuron
  • "Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells" (2021), published in Developmental Cell
  • "Afadin regulates actomyosin organization through αE-catenin at adherens junctions" (2020), published in The Journal of Cell Biology
  • "Nectin-2 in general and in the brain" (2021), published in Molecular and Cellular Biochemistry
  • "Nectins and Nectin-like molecules in synapse formation and involvement in neurological diseases" (2021), published in Molecular and Cellular Neuroscience

Yoshimi Takai frequently collaborates with several co-authors including Kiyohito Mizutani, Muneaki Miyata, Takeshi Kameyama, Hajime Shiotani, and Tomohiko Maruo.

Their research contributions have appeared multiple times in key scientific journals. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), The Journal of Cell Biology, iScience, Journal of Biological Chemistry, and Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature.

Best Publications

  • Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters

    M Castagna;Y Takai;K Kaibuchi;K Sano

  • Small GTP-Binding Proteins

    Yoshimi Takai;Takuya Sasaki;Takashi Matozaki

  • Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

    A. Kishimoto;Y. Takai;T. Mori;U. Kikkawa

  • Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.

    Y Takai;A Kishimoto;Y Iwasa;Y Kawahara

  • Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

    U Kikkawa;Y Takai;R Minakuchi;S Inohara

  • Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

    U Kikkawa;Y Takai;Y Tanaka;R Miyake

  • Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

    M Inoue;A Kishimoto;Y Takai;Y Nishizuka

  • Binding of neuroligins to PSD-95

    M. Irie;Y. Hata;Y. Hata;M. Takeuchi;M. Takeuchi;K. Ichtchenko;K. Ichtchenko

  • Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.

    K Kaibuchi;Y Takai;M Sawamura;M Hoshijima

  • Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system

    Yoshimi Takai;Akira Kishimoto;Ushio Kikkawa;Terutoshi Mori

  • Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

    Hiroaki Miki;Takuya Sasaki;Yoshimi Takai;Tadaomi Takenawa

  • Nectin and afadin: novel organizers of intercellular junctions.

    Yoshimi Takai;Hiroyuki Nakanishi

  • Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells

    Kenji Takaishi;Takuya Sasaki;Hirokazu Kotani;Hideo Nishioka

  • Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway.

    M Hirao;N Sato;T Kondo;S Yonemura

  • Small GTP-binding proteins.

    Yoshimi Takai;Kozo Kaibuchi;Akira Kikuchi;Masahito Kawata

  • Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation

    Yoshimi Takai;Jun Miyoshi;Wataru Ikeda;Hisakazu Ogita

  • Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein.

    Kenichi Takahashi;Hiroyuki Nakanishi;Masako Miyahara;Kenji Mandai

  • Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein

    Kazuo Takahashi;Takuya Sasaki;Akiko Mammoto;Kenji Takaishi

  • cAMP-GEFII is a direct target of cAMP in regulated exocytosis.

    Nobuaki Ozaki;Tadao Shibasaki;Yasushige Kashima;Takashi Miki

  • Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease

    Shigeru Shibata;Miki Nagase;Shigetaka Yoshida;Wakako Kawarazaki

Frequent Co-Authors

Kozo Kaibuchi
Kozo Kaibuchi Nagoya University
Hiroyuki Nakanishi
Hiroyuki Nakanishi Kumamoto University
Akira Kikuchi
Akira Kikuchi Osaka University
Akira Mizoguchi
Akira Mizoguchi Mie University
Yasutomi Nishizuka
Yasutomi Nishizuka Kobe University
Kenji Irie
Kenji Irie University of Tsukuba
Yutaka Hata
Yutaka Hata Tokyo Medical and Dental University
Shinya Kuroda
Shinya Kuroda University of Tokyo
Yoshiharu Matsuura
Yoshiharu Matsuura Osaka University
Ushio Kikkawa
Ushio Kikkawa Kobe University

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