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Yoshinori Nozawa

Yoshinori Nozawa

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
30070
World Ranking
2544
National Ranking
159

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His main research concerns Biochemistry, Molecular biology, Phospholipase C, Phosphatidylinositol and Protein kinase C. His study in Biochemistry concentrates on Membrane, Phosphatidylcholine, Tetrahymena, Membrane fluidity and Arachidonic acid. His Molecular biology research includes elements of Protein kinase A, Phospholipase, Phospholipase D, Pertussis toxin and Inositol.

His work investigates the relationship between Phospholipase C and topics such as EGTA that intersect with problems in Phosphoinositide phospholipase C. Yoshinori Nozawa works mostly in the field of Phosphatidylinositol, limiting it down to topics relating to Phosphatidic acid and, in certain cases, Platelet activation, as a part of the same area of interest. Yoshinori Nozawa focuses mostly in the field of Protein kinase C, narrowing it down to matters related to Cytosol and, in some cases, Keratinocyte.

His most cited work include:

  • Further studies of the lipid composition and biochemical properties of Tetrahymena pyriformis membrane systems. (638 citations)
  • Characterization of Two Alternately Spliced Forms of Phospholipase D1 ACTIVATION OF THE PURIFIED ENZYMES BY PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE, ADP-RIBOSYLATION FACTOR, AND RHO FAMILY MONOMERIC GTP-BINDING PROTEINS AND PROTEIN KINASE C-α (487 citations)
  • Cloning and Disruption of caPLB1, a Phospholipase B Gene Involved in the Pathogenicity of Candida albicans (211 citations)

What are the main themes of his work throughout his whole career to date?

Yoshinori Nozawa mainly investigates Biochemistry, Molecular biology, Internal medicine, Cell biology and Membrane. Tetrahymena, Tetrahymena pyriformis, Phospholipid, Phosphatidylcholine and Phosphatidylinositol are the primary areas of interest in his Biochemistry study. His work carried out in the field of Phosphatidylinositol brings together such families of science as Platelet, Arachidonic acid and Phosphatidic acid.

The various areas that he examines in his Molecular biology study include GTP-binding protein regulators, G protein, Phospholipase D, Protein kinase C and Phospholipase C. His Protein kinase C research is multidisciplinary, incorporating perspectives in Protein kinase A and Cytosol. As a part of the same scientific study, he usually deals with the Internal medicine, concentrating on Endocrinology and frequently concerns with Intracellular and Inositol.

He most often published in these fields:

  • Biochemistry (52.31%)
  • Molecular biology (17.49%)
  • Internal medicine (15.10%)

What were the highlights of his more recent work (between 1994-2020)?

  • Molecular biology (17.49%)
  • Biochemistry (52.31%)
  • Phospholipase D (8.27%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Molecular biology, Biochemistry, Phospholipase D, Internal medicine and Cell biology. His work in Molecular biology addresses subjects such as Peptide sequence, which are connected to disciplines such as Nucleic acid sequence. His research in Tetrahymena pyriformis, Tetrahymena, Phosphatidylcholine, Extracellular and Diacylglycerol kinase are components of Biochemistry.

His research integrates issues of Phosphatidic acid, Tyrosine phosphorylation, Protein kinase C, Phospholipase C and RHOA in his study of Phospholipase D. His Internal medicine study integrates concerns from other disciplines, such as Endocrinology and Cardiology. His biological study spans a wide range of topics, including Cell culture, Membrane and Ceramide.

Between 1994 and 2020, his most popular works were:

  • Characterization of Two Alternately Spliced Forms of Phospholipase D1 ACTIVATION OF THE PURIFIED ENZYMES BY PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE, ADP-RIBOSYLATION FACTOR, AND RHO FAMILY MONOMERIC GTP-BINDING PROTEINS AND PROTEIN KINASE C-α (487 citations)
  • Cloning and Disruption of caPLB1, a Phospholipase B Gene Involved in the Pathogenicity of Candida albicans (211 citations)
  • Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines. (161 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

Yoshinori Nozawa mainly focuses on Molecular biology, Biochemistry, Phospholipase D, Protein kinase C and Protein kinase A. His Molecular biology research incorporates themes from Cell culture, Phospholipase, Candida albicans, Phospholipase C and MAP kinase kinase kinase. His Phospholipase C study incorporates themes from Tyrosine kinase and Thrombin.

His is involved in several facets of Biochemistry study, as is seen by his studies on Extracellular, Phosphatidylcholine, Cytosol, HL60 and Apoptosis. He has included themes like Phosphatidylinositol, Phosphorylation, Diacylglycerol kinase and RHOA in his Phospholipase D study. His Protein kinase C study combines topics from a wide range of disciplines, such as PLD2, Isozyme and MAP2K7.

Best Publications

  • Further studies of the lipid composition and biochemical properties of Tetrahymena pyriformis membrane systems.

    Guy A. Thompson;Raymond J. Bambery;Yoshinori Nozawa

  • Characterization of Two Alternately Spliced Forms of Phospholipase D1 ACTIVATION OF THE PURIFIED ENZYMES BY PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE, ADP-RIBOSYLATION FACTOR, AND RHO FAMILY MONOMERIC GTP-BINDING PROTEINS AND PROTEIN KINASE C-α

    Scott M. Hammond;John M. Jenco;Shigeru Nakashima;Karen Cadwallader

  • Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells.

    Yasunori Fujita;Keitaro Kojima;Nanako Hamada;Riyako Ohhashi

  • Anti-cancer effects of xanthones from pericarps of mangosteen.

    Yukihiro Akao;Yoshihito Nakagawa;Munekazu Iinuma;Yoshinori Nozawa

  • Cloning and Disruption of caPLB1, a Phospholipase B Gene Involved in the Pathogenicity of Candida albicans

    Steven D. Leidich;Ashraf S. Ibrahim;Yue Fu;Anjni Koul

  • Ceramide Formation Leads to Caspase-3 Activation during Hypoxic PC12 Cell Death INHIBITORY EFFECTS OF Bcl-2 ON CERAMIDE FORMATION AND CASPASE-3 ACTIVATION

    Shin-ichi Yoshimura;Yoshiko Banno;Shigeru Nakashima;Katsunobu Takenaka

  • Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines.

    Kenji Matsumoto;Yukihiro Akao;Emi Kobayashi;Kenji Ohguchi

  • Bradykinin-induced rapid breakdown of phosphatidylinositol 4,5-bisphosphate in neuroblastoma X glioma hybrid NG108-15 cells.

    K Yano;H Higashida;R Inoue;Y Nozawa

  • Preferential target is mitochondria in α-mangostin-induced apoptosis in human leukemia HL60 cells

    Kenji Matsumoto;Yukihiro Akao;Hong Yi;Kenji Ohguchi

  • MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5.

    Tomohiro Itoh;Yoshinori Nozawa;Yukihiro Akao

  • Biochemical Characterization and Biologic Actions of Two Toxins (D-l and D-2) from Clostridium difficile

    Yoshiko Banno;Toyoko Kobayashi;Hideki Kono;Kunitomo Watanabe

  • MiR‐34a attenuates paclitaxel‐resistance of hormone‐refractory prostate cancer PC3 cells through direct and indirect mechanisms

    Keitaro Kojima;Yasunori Fujita;Yoshinori Nozawa;Yoshinori Nozawa;Takashi Deguchi

  • MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression

    Yasunori Fujita;Keitaro Kojima;Keitaro Kojima;Riyako Ohhashi;Nanako Hamada

  • Cell growth inhibitory effect of cinnamic acid derivatives from propolis on human tumor cell lines.

    Yukihiro Akao;Hiroe Maruyama;Kenji Matsumoto;Kenji Ohguchi

  • Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells.

    Kenji Matsumoto;Yukihiro Akao;Kenji Ohguchi;Tetsuro Ito

  • Characterized mechanism of α-mangostin-induced cell death : Caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells

    Yoshihito Nakagawa;Munekazu Iinuma;Tomoki Naoe;Yoshinori Nozawa

  • A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells.

    Keitaro Kojima;Riyako Ohhashi;Yasunori Fujita;Nanako Hamada

  • Molecular control of membrane properties during temperature acclimation. Fatty acid desaturase regulation of membrane fluidity in acclimating Tetrahymena cells.

    Charles E. Martin;Kayoko Hiramitsu;Yasuo Kitajima;Yoshinori Nozawa

  • Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11

    Koh-ichi Nagata;Tomiko Asano;Yoshinori Nozawa;Masaki Inagaki

  • Inhibitory action of cyclic GMP on secretion, polyphosphoinositide hydrolysis and calcium mobilization in thrombin-stimulated human platelets.

    Shigeru Nakashima;Toyohiko Tohmatsu;Hiroaki Hattori;Yukio Okano

Frequent Co-Authors

Shigeru Nakashima
Shigeru Nakashima Gifu University
Yoshiko Banno
Yoshiko Banno Gifu University
Kei Satoh
Kei Satoh Hirosaki University
Yoshiji Yamada
Yoshiji Yamada Mie University
Haruhiro Higashida
Haruhiro Higashida Kanazawa University
Yukihiro Akao
Yukihiro Akao Gifu University
Hideki Mori
Hideki Mori Gifu University
Hideo Kanoh
Hideo Kanoh Sapporo Medical University
Keizo Inoue
Keizo Inoue University of Tokyo
Mahmoud A. Ghannoum
Mahmoud A. Ghannoum Case Western Reserve University

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