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Yukihiro Akao

Yukihiro Akao

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
20379
World Ranking
3757
National Ranking
244

Overview

Yukihiro Akao is affiliated with Gifu University in Japan and has a research focus spanning biochemistry, genetics, molecular biology, and medicine. Their work concentrates extensively on molecular biology and cancer research, with additional contributions in oncology, pathology, forensic medicine, and epidemiology.

Their research topics include:

  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Circular RNAs in diseases
  • Extracellular vesicles in disease
  • RNA modifications and cancer
  • Cancer mechanisms and therapy
  • RNA interference and gene delivery

Yukihiro Akao has published in a variety of scientific journals, frequently contributing to:

  • Cancer Science
  • Scientific Reports
  • International Journal of Molecular Sciences
  • Molecular Therapy - Nucleic Acids
  • Journal of Clinical Medicine

Some recent papers authored or co-authored by Yukihiro Akao include:

  • PTBP1-targeting microRNAs regulate cancer-specific energy metabolism through the modulation of PKM1/M2 splicing (2020), Cancer Science
  • Comparative lipidomics of 5-Fluorouracil-sensitive and -resistant colorectal cancer cells reveals altered sphingomyelin and ceramide controlled by acid sphingomyelinase (SMPD1) (2020), Scientific Reports
  • High Expression of microRNA-143 is Associated with Favorable Tumor Immune Microenvironment and Better Survival in Estrogen Receptor Positive Breast Cancer (2020), International Journal of Molecular Sciences
  • High Expression of miR-34a Associated with Less Aggressive Cancer Biology but Not with Survival in Breast Cancer (2020), International Journal of Molecular Sciences
  • Downregulation of miR-122-5p Activates Glycolysis via PKM2 in Kupffer Cells of Rat and Mouse Models of Non-Alcoholic Steatohepatitis (2022), International Journal of Molecular Sciences

Yukihiro Akao frequently collaborates with several co-authors, including:

  • Nobuhiko Sugito (14 collaborations)
  • Kazuki Heishima (14 collaborations)
  • Yuko Ito (6 collaborations)
  • Kohei Taniguchi (5 collaborations)
  • Yoshihisa Tokumaru (5 collaborations)

Best Publications

  • let-7 microRNA functions as a potential growth suppressor in human colon cancer cells.

    Yukihiro Akao;Yoshihito Nakagawa;Tomoki Naoe

  • Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells.

    Yasunori Fujita;Keitaro Kojima;Nanako Hamada;Riyako Ohhashi

  • MicroRNAs 143 and 145 are possible common onco-microRNAs in human cancers

    Yukihiro Akao;Yoshihito Nakagawa;Tomoki Naoe

  • Decreased expression of microRNA-143 and -145 in human gastric cancers.

    Takeshi Takagi;Akio Iio;Yoshihito Nakagawa;Tomoki Naoe

  • Anti-cancer effects of xanthones from pericarps of mangosteen.

    Yukihiro Akao;Yoshihito Nakagawa;Munekazu Iinuma;Yoshinori Nozawa

  • Downregulation of microRNAs-143 and -145 in B-cell malignancies

    Yukihiro Akao;Yoshihito Nakagawa;Yukio Kitade;Tomohiro Kinoshita

  • Microvesicle-mediated RNA Molecule Delivery System Using Monocytes/Macrophages

    Yukihiro Akao;Akio Iio;Tomohiro Itoh;Shunsuke Noguchi

  • Role of anti-oncomirs miR-143 and -145 in human colorectal tumors

    Y Akao;Y Akao;Y Nakagawa;I Hirata;A Iio

  • Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines.

    Kenji Matsumoto;Yukihiro Akao;Emi Kobayashi;Kenji Ohguchi

  • MicroRNA-143 and -145 in colon cancer.

    Yukihiro Akao;Yoshihito Nakagawa;Tomoki Naoe

  • Gene therapy for mitochondrial disease by delivering restriction endonuclease SmaI into mitochondria.

    Masashi Tanaka;Harm-Jan Borgeld;Jin Zhang;Shin-ichi Muramatsu

  • Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro

    Yukihiro Akao;Yoshihito Nakagawa;Kiyotaka Akiyama

  • Preferential target is mitochondria in α-mangostin-induced apoptosis in human leukemia HL60 cells

    Kenji Matsumoto;Yukihiro Akao;Hong Yi;Kenji Ohguchi

  • MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5.

    Tomohiro Itoh;Yoshinori Nozawa;Yukihiro Akao

  • Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol.

    Wakako Maruyama;Yukihiro Akao;Moussa B. H. Youdim;Bruce A. Davis

  • Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells

    Yukihiro Akao;Shunsuke Noguchi;Akio Iio;Keitaro Kojima

  • Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl-2 and rasagiline, N-propargyl-1(R)-aminoindan.

    Yukihiro Akao;Wakako Maruyama;Shigeomi Shimizu;Hong Yi

  • Cell growth inhibitory effect of cinnamic acid derivatives from propolis on human tumor cell lines.

    Yukihiro Akao;Hiroe Maruyama;Kenji Matsumoto;Kenji Ohguchi

  • Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells.

    Kenji Matsumoto;Yukihiro Akao;Kenji Ohguchi;Tetsuro Ito

  • Neuroprotection by propargylamines in Parkinson's disease : suppression of apoptosis and induction of prosurvival genes

    Wakako Maruyama;Yukihiro Akao;Maria Chrisina Carrillo;Ken-ichi Kitani

Frequent Co-Authors

Munekazu Iinuma
Munekazu Iinuma Gifu Pharmaceutical University
Tomoki Naoe
Tomoki Naoe Nagoya University
Yoshinori Nozawa
Yoshinori Nozawa Gifu University
Makoto Naoi
Makoto Naoi Nagoya Institute of Technology
Yoshiko Banno
Yoshiko Banno Gifu University
Toshiyuki Tanaka
Toshiyuki Tanaka Hyogo University of Health Sciences
Yoshiji Yamada
Yoshiji Yamada Mie University
Masao Seto
Masao Seto Kurume University
Ryuzo Ueda
Ryuzo Ueda Nagoya University
Masashi Tanaka
Masashi Tanaka Juntendo University

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