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Yukihiro Akao

Yukihiro Akao

Gifu University
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
20379
World Ranking
3757
National Ranking
244

Yukihiro Akao publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Yukihiro Akao sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 285 publications — 75th percentile

75% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Yukihiro Akao D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Yukihiro Akao sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 82 D-Index — 82nd percentile

82% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Yukihiro Akao is affiliated with Gifu University in Japan and has a research focus spanning biochemistry, genetics, molecular biology, and medicine. Their work concentrates extensively on molecular biology and cancer research, with additional contributions in oncology, pathology, forensic medicine, and epidemiology.

Their research topics include:

  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Circular RNAs in diseases
  • Extracellular vesicles in disease
  • RNA modifications and cancer
  • Cancer mechanisms and therapy
  • RNA interference and gene delivery

Yukihiro Akao has published in a variety of scientific journals, frequently contributing to:

  • Cancer Science
  • Scientific Reports
  • International Journal of Molecular Sciences
  • Molecular Therapy - Nucleic Acids
  • Journal of Clinical Medicine

Some recent papers authored or co-authored by Yukihiro Akao include:

  • PTBP1-targeting microRNAs regulate cancer-specific energy metabolism through the modulation of PKM1/M2 splicing (2020), Cancer Science
  • Comparative lipidomics of 5-Fluorouracil-sensitive and -resistant colorectal cancer cells reveals altered sphingomyelin and ceramide controlled by acid sphingomyelinase (SMPD1) (2020), Scientific Reports
  • High Expression of microRNA-143 is Associated with Favorable Tumor Immune Microenvironment and Better Survival in Estrogen Receptor Positive Breast Cancer (2020), International Journal of Molecular Sciences
  • High Expression of miR-34a Associated with Less Aggressive Cancer Biology but Not with Survival in Breast Cancer (2020), International Journal of Molecular Sciences
  • Downregulation of miR-122-5p Activates Glycolysis via PKM2 in Kupffer Cells of Rat and Mouse Models of Non-Alcoholic Steatohepatitis (2022), International Journal of Molecular Sciences

Yukihiro Akao frequently collaborates with several co-authors, including:

  • Nobuhiko Sugito (14 collaborations)
  • Kazuki Heishima (14 collaborations)
  • Yuko Ito (6 collaborations)
  • Kohei Taniguchi (5 collaborations)
  • Yoshihisa Tokumaru (5 collaborations)

Best Publications

  • let-7 microRNA functions as a potential growth suppressor in human colon cancer cells.

    Yukihiro Akao;Yoshihito Nakagawa;Tomoki Naoe

  • Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells.

    Yasunori Fujita;Keitaro Kojima;Nanako Hamada;Riyako Ohhashi

  • MicroRNAs 143 and 145 are possible common onco-microRNAs in human cancers

    Yukihiro Akao;Yoshihito Nakagawa;Tomoki Naoe

  • Decreased expression of microRNA-143 and -145 in human gastric cancers.

    Takeshi Takagi;Akio Iio;Yoshihito Nakagawa;Tomoki Naoe

  • Anti-cancer effects of xanthones from pericarps of mangosteen.

    Yukihiro Akao;Yoshihito Nakagawa;Munekazu Iinuma;Yoshinori Nozawa

  • Downregulation of microRNAs-143 and -145 in B-cell malignancies

    Yukihiro Akao;Yoshihito Nakagawa;Yukio Kitade;Tomohiro Kinoshita

  • Microvesicle-mediated RNA Molecule Delivery System Using Monocytes/Macrophages

    Yukihiro Akao;Akio Iio;Tomohiro Itoh;Shunsuke Noguchi

  • Role of anti-oncomirs miR-143 and -145 in human colorectal tumors

    Y Akao;Y Akao;Y Nakagawa;I Hirata;A Iio

  • Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines.

    Kenji Matsumoto;Yukihiro Akao;Emi Kobayashi;Kenji Ohguchi

  • MicroRNA-143 and -145 in colon cancer.

    Yukihiro Akao;Yoshihito Nakagawa;Tomoki Naoe

  • Gene therapy for mitochondrial disease by delivering restriction endonuclease SmaI into mitochondria.

    Masashi Tanaka;Harm-Jan Borgeld;Jin Zhang;Shin-ichi Muramatsu

  • Arsenic trioxide induces apoptosis in neuroblastoma cell lines through the activation of caspase 3 in vitro

    Yukihiro Akao;Yoshihito Nakagawa;Kiyotaka Akiyama

  • Preferential target is mitochondria in α-mangostin-induced apoptosis in human leukemia HL60 cells

    Kenji Matsumoto;Yukihiro Akao;Hong Yi;Kenji Ohguchi

  • MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5.

    Tomohiro Itoh;Yoshinori Nozawa;Yukihiro Akao

  • Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol.

    Wakako Maruyama;Yukihiro Akao;Moussa B. H. Youdim;Bruce A. Davis

  • Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells

    Yukihiro Akao;Shunsuke Noguchi;Akio Iio;Keitaro Kojima

  • Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl-2 and rasagiline, N-propargyl-1(R)-aminoindan.

    Yukihiro Akao;Wakako Maruyama;Shigeomi Shimizu;Hong Yi

  • Cell growth inhibitory effect of cinnamic acid derivatives from propolis on human tumor cell lines.

    Yukihiro Akao;Hiroe Maruyama;Kenji Matsumoto;Kenji Ohguchi

  • Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells.

    Kenji Matsumoto;Yukihiro Akao;Kenji Ohguchi;Tetsuro Ito

  • Neuroprotection by propargylamines in Parkinson's disease : suppression of apoptosis and induction of prosurvival genes

    Wakako Maruyama;Yukihiro Akao;Maria Chrisina Carrillo;Ken-ichi Kitani

Frequent Co-Authors

Munekazu Iinuma
Munekazu Iinuma Gifu Pharmaceutical University
Tomoki Naoe
Tomoki Naoe Nagoya University
Yoshinori Nozawa
Yoshinori Nozawa Gifu University
Makoto Naoi
Makoto Naoi Nagoya Institute of Technology
Yoshiko Banno
Yoshiko Banno Gifu University
Toshiyuki Tanaka
Toshiyuki Tanaka Hyogo University of Health Sciences
Yoshiji Yamada
Yoshiji Yamada Mie University
Masao Seto
Masao Seto Kurume University
Ryuzo Ueda
Ryuzo Ueda Nagoya University
Masashi Tanaka
Masashi Tanaka Juntendo University

External Links

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Best Scientists Citing Yukihiro Akao

Moussa B.H. Youdim

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Publications: 55

Tamar Amit

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Technion – Israel Institute of Technology

Publications: 46

Carlo M. Croce

Carlo M. Croce

The Ohio State University

Publications: 45

Munekazu Iinuma

Munekazu Iinuma

Gifu Pharmaceutical University

Publications: 35

George A. Calin

George A. Calin

The University of Texas MD Anderson Cancer Center

Publications: 32

Yoshiko Banno

Yoshiko Banno

Gifu University

Publications: 28

Behzad Baradaran

Behzad Baradaran

Tabriz University of Medical Sciences

Publications: 19

Do Sik Min

Do Sik Min

Yonsei University

Publications: 18

Kazuaki Takabe

Kazuaki Takabe

Roswell Park Cancer Institute

Publications: 18

Ajay Goel

Ajay Goel

City Of Hope National Medical Center

Publications: 18

Peter Riederer

Peter Riederer

University of Würzburg

Publications: 18

Fazlul H. Sarkar

Fazlul H. Sarkar

Wayne State University

Publications: 17

Tetsuhito Kojima

Tetsuhito Kojima

Nagoya University

Publications: 17

Carlos T. Moraes

Carlos T. Moraes

University of Miami

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Lina M. Obeid

Lina M. Obeid

Stony Brook University

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