What is he best known for?
The fields of study he is best known for:
His primary areas of study are Cell biology, Receptor, Apoptosis, Signal transduction and Ceramide.
His Cell biology research is multidisciplinary, incorporating elements of Cell culture, Biochemistry, N-Acetylneuraminic acid and Cell adhesion, Neural cell adhesion molecule.
His work deals with themes such as Cell and Molecular biology, which intersect with Receptor.
His research integrates issues of Cell surface receptor and Intracellular in his study of Signal transduction.
His studies in Intracellular integrate themes in fields like Lymphocyte and Ligand.
His study in Ceramide is interdisciplinary in nature, drawing from both Sphingomyelin, Programmed cell death, Mitochondrial permeability transition pore, Apoptosis-inducing factor and Mitochondrion.
His most cited work include:
- Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. (538 citations)
- Potential Involvement of Fas and Its Ligand in the Pathogenesis of Hashimoto's Thyroiditis (513 citations)
- The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells (411 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Cell biology, Apoptosis, Frataxin, Ataxia and Cancer research.
His studies deal with areas such as Ceramide and Biochemistry as well as Cell biology.
As part of the same scientific family, Roberto Testi usually focuses on Apoptosis, concentrating on Immunology and intersecting with In vivo, Secretion and Aminosalicylic acid.
His Frataxin study combines topics in areas such as Ubiquitin, Aconitase and Iron-binding proteins.
In his study, which falls under the umbrella issue of Cancer research, Tyrosine kinase is strongly linked to Proto-oncogene tyrosine-protein kinase Src.
His research integrates issues of Receptor and Cell type in his study of Signal transduction.
He most often published in these fields:
- Cell biology (45.08%)
- Apoptosis (31.15%)
- Frataxin (21.31%)
What were the highlights of his more recent work (between 2011-2020)?
- Ataxia (18.85%)
- Frataxin (21.31%)
- Cell biology (45.08%)
In recent papers he was focusing on the following fields of study:
Ataxia, Frataxin, Cell biology, Cancer research and Gene silencing are his primary areas of study.
The various areas that Roberto Testi examines in his Ataxia study include Clinical trial, Mutation, Gene, Immunology and Interferon gamma.
His Frataxin study is concerned with the larger field of Mitochondrion.
The study incorporates disciplines such as Downregulation and upregulation and Proto-oncogene tyrosine-protein kinase Src in addition to Cancer research.
His Downregulation and upregulation research includes elements of Molecular biology and Cell type.
Ubiquitin is a subfield of Biochemistry that he tackles.
Between 2011 and 2020, his most popular works were:
- Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans (49 citations)
- Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model (43 citations)
- Highly specific ubiquitin-competing molecules effectively promote frataxin accumulation and partially rescue the aconitase defect in Friedreich ataxia cells. (25 citations)
In his most recent research, the most cited papers focused on:
Roberto Testi mainly focuses on Frataxin, Ataxia, Cell biology, Ubiquitin and Biochemistry.
Roberto Testi interconnects Protein degradation, Caenorhabditis elegans, Interferon gamma and Iron-binding proteins in the investigation of issues within Frataxin.
His Caenorhabditis elegans research is multidisciplinary, incorporating perspectives in Autophagy, Cellular adaptation, Lipid metabolism, RNA interference and Gene silencing.
His Ataxia research is multidisciplinary, incorporating elements of Peripheral blood mononuclear cell and Pathology.
His Ubiquitin study incorporates themes from HEK 293 cells, Aconitase, Programmed cell death and Proteasome.
His work deals with themes such as Molecular biology, Cancer research, Downregulation and upregulation and Cell type, which intersect with Mitochondrion.
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