World's Best Scientists 2026 revealed!
Carlo Federico Perno

Carlo Federico Perno

D-Index & Metrics

Immunology

D-Index
82
Citations
26270
World Ranking
1497
National Ranking
60

Medicine

D-Index
82
Citations
26301
World Ranking
16050
National Ranking
634

Overview

Carlo Federico Perno is affiliated with the University of Milan in Italy. Their research focuses predominantly on the field of Medicine, with particular attention to Infectious Diseases, Epidemiology, and Virology. Their work also extends into related subfields such as Hepatology and Immunology.

The scientist has contributed extensively to studies on viral infections and treatment developments in the context of HIV/AIDS and SARS-CoV-2. Their research covers several main topics, including:

  • HIV/AIDS drug development and treatment
  • HIV Research and Treatment
  • SARS-CoV-2 and COVID-19 Research
  • HIV/AIDS Research and Interventions
  • COVID-19 Clinical Research Studies
  • Respiratory viral infections research
  • SARS-CoV-2 detection and testing

Their publication record includes work in a variety of scientific journals. The venues where they frequently publish encompass:

  • Journal of Antimicrobial Chemotherapy
  • Viruses
  • PLoS ONE
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators in their research include Francesca Ceccherini-Silberstein, Luna Colagrossi, Maria Mercedes Santoro, Vittorio Colizzi, and Joseph Fokam, with coauthoring counts ranging from over 50 to more than 80 joint works.

Selected recent papers by Carlo Federico Perno include:

  • "Multicenter Evaluation of the Cepheid Xpert Xpress SARS-CoV-2 Test," 2020, Journal of Clinical Microbiology
  • "Exploring predictors of HIV-1 virologic failure to long-acting cabotegravir and rilpivirine: a multivariable analysis," 2021, AIDS
  • "Clinical and Analytical Performance of an Automated Serological Test That Identifies S1/S2-Neutralizing IgG in COVID-19 Patients Semiquantitatively," 2020, Journal of Clinical Microbiology
  • "Genomic epidemiology of SARS-CoV-2 reveals multiple lineages and early spread of SARS-CoV-2 infections in Lombardy, Italy," 2021, Nature Communications
  • "Safety and efficacy of anti-il6-receptor tocilizumab use in severe and critical patients affected by coronavirus disease 2019: A comparative analysis," 2020, Journal of Infection

Best Publications

  • 1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D- ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"-oxathiole 2",2"-dioxide) (TSAO) analogues: synthesis and anti-HIV-1 activity.

    Rosa Alvarez;Sonsoles Velázquez;Ana San-Félix;Stefano Aquaro

  • PHASE I STUDIES OF 2',3'-DIDEOXYCYTIDINE IN SEVERE HUMAN IMMUNODEFICIENCY VIRUS INFECTION AS A SINGLE AGENT AND ALTERNATING WITH ZIDOVUDINE (AZT)

    Robert Yarchoan;Rose V. Thomas;Jean Pierre Allain;Nanette Mcatee

  • In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine

    Robert Yarchoan;Hiroaki Mitsuya;Rose V. Thomas;James M. Pluda

  • Response of human-immunodeficiency-virus-associated neurological disease to 3'-azido-3'-deoxythymidine.

    Robert Yarchoan;Robert Yarchoan;Pim Brouwers;Pim Brouwers;A. Robert Spitzer;A. Robert Spitzer;Jordan Grafman;Jordan Grafman;Jordan Grafman

  • Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.

    C.-F. Perno;R. Yarchoan;D. A. Cooney;N. R. Hartman

  • Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative.

    M. Baba;H. Tanaka;E. De Clercq;R. Pauwels

  • Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides.

    C F Perno;R Yarchoan;D A Cooney;N R Hartman

  • European guidelines on the clinical management of HIV-1 tropism testing

    L.P.R. Vandekerckhove;Annemarie Wensing;Rolf Kaiser;F. Brun-Vézinet

  • Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study

    John Gregson;Michele Tang;Nicaise Ndembi;Raph L Hamers

  • Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir.

    Stefano Aquaro;Raffaele Caliò;Jan Balzarini;Maria Concetta Bellocchi

  • 2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.

    Jan Balzarini;María Jesús Pérez-Pérez;Ana San-Félix;Dominique Schols

  • Factors determining the activity of 2',3'-dideoxynucleosides in suppressing human immunodeficiency virus in vitro.

    Z Hao;D A Cooney;N R Hartman;C F Perno

  • Therapeutic drug monitoring in HIV infection: current status and future directions.

    David J. Back;Giorgio Gatti;Courtney Fletcher;Rodolphe Garaffo

  • HIV-1 Genetic Variability and Clinical Implications.

    Maria Mercedes Santoro;Carlo Federico Perno

  • Cytomegalovirus Coinfection Is Associated With an Increased Risk of Severe Non–AIDS-Defining Events in a Large Cohort of HIV-Infected Patients

    Miriam Lichtner;Paola Cicconi;Serena Vita;Alessandro Cozzi-Lepri

  • Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants

    Vincenzo Mollace;Hans S.L.M. Nottet;Pascal Clayette;Maria C. Turco

  • Mannose-Specific Plant Lectins from the Amaryllidaceae Family Qualify as Efficient Microbicides for Prevention of Human Immunodeficiency Virus Infection

    Jan Balzarini;Sigrid Hatse;Kurt Vermeire;Katrien Princen

  • Hepatitis C virus drug resistance associated substitutions and their clinical relevance: Update 2018.

    Maria C. Sorbo;Valeria Cento;Velia C. Di Maio;Anita Y.M. Howe

  • Relative Potency of Protease Inhibitors in Monocytes/Macrophages Acutely and Chronically Infected with Human Immunodeficiency Virus

    Carlo Federico Perno;Fonda M. Newcomb;David A. Davis;Stefano Aquaro

  • A genotypic drug resistance interpretation algorithm that significantly predicts therapy response in HIV-1-infected patients.

    Kristel Van Laethem;Andrea De Luca;Andrea Antinori;Antonello Cingolani

Frequent Co-Authors

Francesca Ceccherini-Silberstein
Francesca Ceccherini-Silberstein University of Rome Tor Vergata
Andrea Antinori
Andrea Antinori Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani
Massimo Andreoni
Massimo Andreoni University of Rome Tor Vergata
Massimo Ciccozzi
Massimo Ciccozzi Università Campus Bio-Medico
Antonella d'Arminio Monforte
Antonella d'Arminio Monforte University of Milan
Cristina Mussini
Cristina Mussini University of Modena and Reggio Emilia
Jan Balzarini
Jan Balzarini KU Leuven
Claudio Maria Mastroianni
Claudio Maria Mastroianni Sapienza University of Rome
Adriana Ammassari
Adriana Ammassari Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani
Adriano Lazzarin
Adriano Lazzarin Vita-Salute San Raffaele University

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