His main research concerns Virology, Immunology, Virus, Internal medicine and Reverse transcriptase. His work carried out in the field of Virology brings together such families of science as Molecular biology and Genotype. His Immunology study incorporates themes from HIV drug resistance and Acquired immunodeficiency syndrome.
His Virus research incorporates elements of Cytotoxic T cell and Microbiology. His study in Internal medicine is interdisciplinary in nature, drawing from both Gastroenterology and Lamivudine. Carlo Federico Perno has included themes like Nevirapine, DNA polymerase, Drug resistance and Nucleotidyltransferase in his Reverse transcriptase study.
His primary areas of investigation include Virology, Immunology, Internal medicine, Virus and Drug resistance. His Virology research includes themes of Mutation, Reverse transcriptase and Genotype. His research in Immunology intersects with topics in Transmission, Acquired immunodeficiency syndrome and Intensive care medicine.
His Internal medicine research is multidisciplinary, incorporating elements of Gastroenterology, Viral load and Oncology. His Virus research integrates issues from Cell culture and In vitro. His Drug resistance research incorporates themes from Integrase inhibitor, HIV drug resistance and Antiretroviral therapy.
His scientific interests lie mostly in Internal medicine, Virology, Viral load, Gastroenterology and Severe acute respiratory syndrome coronavirus 2. The various areas that Carlo Federico Perno examines in his Internal medicine study include NS5A, Drug resistance and Antiretroviral therapy. His studies in Drug resistance integrate themes in fields like Transmission, Adverse effect and Resistance mutation.
His Virology study integrates concerns from other disciplines, such as In vitro, In vivo and Ritonavir. The Viral load study combines topics in areas such as HIV drug resistance, Viral suppression and Raltegravir. His Gastroenterology study combines topics in areas such as NS5B and Sofosbuvir.
Carlo Federico Perno mainly focuses on Internal medicine, Virology, Severe acute respiratory syndrome coronavirus 2, Gastroenterology and Viral load. His Internal medicine research includes themes of Viremia and Chronic infection. Carlo Federico Perno studies Virology, focusing on Virus in particular.
His research on Severe acute respiratory syndrome coronavirus 2 also deals with topics like
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1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D- ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"-oxathiole 2",2"-dioxide) (TSAO) analogues: synthesis and anti-HIV-1 activity.
Rosa Alvarez;Sonsoles Velázquez;Ana San-Félix;Stefano Aquaro.
Journal of Medicinal Chemistry (1994)
PHASE I STUDIES OF 2',3'-DIDEOXYCYTIDINE IN SEVERE HUMAN IMMUNODEFICIENCY VIRUS INFECTION AS A SINGLE AGENT AND ALTERNATING WITH ZIDOVUDINE (AZT)
Robert Yarchoan;Rose V. Thomas;Jean Pierre Allain;Nanette Mcatee.
The Lancet (1988)
In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine
Robert Yarchoan;Hiroaki Mitsuya;Rose V. Thomas;James M. Pluda.
Science (1989)
Response of human-immunodeficiency-virus-associated neurological disease to 3'-azido-3'-deoxythymidine.
Robert Yarchoan;Robert Yarchoan;Pim Brouwers;Pim Brouwers;A. Robert Spitzer;A. Robert Spitzer;Jordan Grafman;Jordan Grafman;Jordan Grafman.
The Lancet (1987)
Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.
C.-F. Perno;R. Yarchoan;D. A. Cooney;N. R. Hartman.
Journal of Experimental Medicine (1989)
Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative.
M. Baba;H. Tanaka;E. De Clercq;R. Pauwels.
Biochemical and Biophysical Research Communications (1989)
Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides.
C F Perno;R Yarchoan;D A Cooney;N R Hartman.
Journal of Experimental Medicine (1988)
European guidelines on the clinical management of HIV-1 tropism testing
L.P.R. Vandekerckhove;Annemarie Wensing;Rolf Kaiser;F. Brun-Vézinet.
Lancet Infectious Diseases (2011)
Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir.
Stefano Aquaro;Raffaele Caliò;Jan Balzarini;Maria Concetta Bellocchi.
Antiviral Research (2002)
2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.
Jan Balzarini;María Jesús Pérez-Pérez;Ana San-Félix;Dominique Schols.
Proceedings of the National Academy of Sciences of the United States of America (1992)
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