D-Index & Metrics Best Publications
Carlo Federico Perno

Carlo Federico Perno

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 78 Citations 20,560 517 World Ranking 1107 National Ranking 37
Medicine D-index 78 Citations 21,166 595 World Ranking 12912 National Ranking 454

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Virus
  • Gene

His main research concerns Virology, Immunology, Virus, Internal medicine and Reverse transcriptase. His work carried out in the field of Virology brings together such families of science as Molecular biology and Genotype. His Immunology study incorporates themes from HIV drug resistance and Acquired immunodeficiency syndrome.

His Virus research incorporates elements of Cytotoxic T cell and Microbiology. His study in Internal medicine is interdisciplinary in nature, drawing from both Gastroenterology and Lamivudine. Carlo Federico Perno has included themes like Nevirapine, DNA polymerase, Drug resistance and Nucleotidyltransferase in his Reverse transcriptase study.

His most cited work include:

  • 1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D- ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"-oxathiole 2",2"-dioxide) (TSAO) analogues: synthesis and anti-HIV-1 activity. (626 citations)
  • PHASE I STUDIES OF 2',3'-DIDEOXYCYTIDINE IN SEVERE HUMAN IMMUNODEFICIENCY VIRUS INFECTION AS A SINGLE AGENT AND ALTERNATING WITH ZIDOVUDINE (AZT) (415 citations)
  • In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine (369 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Virology, Immunology, Internal medicine, Virus and Drug resistance. His Virology research includes themes of Mutation, Reverse transcriptase and Genotype. His research in Immunology intersects with topics in Transmission, Acquired immunodeficiency syndrome and Intensive care medicine.

His Internal medicine research is multidisciplinary, incorporating elements of Gastroenterology, Viral load and Oncology. His Virus research integrates issues from Cell culture and In vitro. His Drug resistance research incorporates themes from Integrase inhibitor, HIV drug resistance and Antiretroviral therapy.

He most often published in these fields:

  • Virology (52.96%)
  • Immunology (25.66%)
  • Internal medicine (25.99%)

What were the highlights of his more recent work (between 2018-2021)?

  • Internal medicine (25.99%)
  • Virology (52.96%)
  • Viral load (11.35%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Internal medicine, Virology, Viral load, Gastroenterology and Severe acute respiratory syndrome coronavirus 2. The various areas that Carlo Federico Perno examines in his Internal medicine study include NS5A, Drug resistance and Antiretroviral therapy. His studies in Drug resistance integrate themes in fields like Transmission, Adverse effect and Resistance mutation.

His Virology study integrates concerns from other disciplines, such as In vitro, In vivo and Ritonavir. The Viral load study combines topics in areas such as HIV drug resistance, Viral suppression and Raltegravir. His Gastroenterology study combines topics in areas such as NS5B and Sofosbuvir.

Between 2018 and 2021, his most popular works were:

  • Safety and efficacy of anti-il6-receptor tocilizumab use in severe and critical patients affected by coronavirus disease 2019: A comparative analysis. (46 citations)
  • Clinical and Analytical Performance of an Automated Serological Test That Identifies S1/S2-Neutralizing IgG in COVID-19 Patients Semiquantitatively. (43 citations)
  • Detection and quantification of SARS-CoV-2 by droplet digital PCR in real-time PCR negative nasopharyngeal swabs from suspected COVID-19 patients. (29 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Virus
  • Gene

Carlo Federico Perno mainly focuses on Internal medicine, Virology, Severe acute respiratory syndrome coronavirus 2, Gastroenterology and Viral load. His Internal medicine research includes themes of Viremia and Chronic infection. Carlo Federico Perno studies Virology, focusing on Virus in particular.

His research on Severe acute respiratory syndrome coronavirus 2 also deals with topics like

  • Coronavirus which intersects with area such as RNA, Hospital discharge and Pandemic,
  • 2019-20 coronavirus outbreak which intersects with area such as Phylogenetics, Prevention control, Single-nucleotide polymorphism and Epidemiology. Within one scientific family, Carlo Federico Perno focuses on topics pertaining to Digital polymerase chain reaction under Gastroenterology, and may sometimes address concerns connected to Antiretroviral treatment and Stage. His Viral load study incorporates themes from Resistance mutation, Reverse transcriptase, Regimen and Lamivudine, Emtricitabine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D- ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"-oxathiole 2",2"-dioxide) (TSAO) analogues: synthesis and anti-HIV-1 activity.

Rosa Alvarez;Sonsoles Velázquez;Ana San-Félix;Stefano Aquaro.
Journal of Medicinal Chemistry (1994)

1024 Citations

PHASE I STUDIES OF 2',3'-DIDEOXYCYTIDINE IN SEVERE HUMAN IMMUNODEFICIENCY VIRUS INFECTION AS A SINGLE AGENT AND ALTERNATING WITH ZIDOVUDINE (AZT)

Robert Yarchoan;Rose V. Thomas;Jean Pierre Allain;Nanette Mcatee.
The Lancet (1988)

649 Citations

In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine

Robert Yarchoan;Hiroaki Mitsuya;Rose V. Thomas;James M. Pluda.
Science (1989)

575 Citations

Response of human-immunodeficiency-virus-associated neurological disease to 3'-azido-3'-deoxythymidine.

Robert Yarchoan;Robert Yarchoan;Pim Brouwers;Pim Brouwers;A. Robert Spitzer;A. Robert Spitzer;Jordan Grafman;Jordan Grafman;Jordan Grafman.
The Lancet (1987)

463 Citations

Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.

C.-F. Perno;R. Yarchoan;D. A. Cooney;N. R. Hartman.
Journal of Experimental Medicine (1989)

407 Citations

Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative.

M. Baba;H. Tanaka;E. De Clercq;R. Pauwels.
Biochemical and Biophysical Research Communications (1989)

391 Citations

Inhibition of human immunodeficiency virus (HIV-1/HTLV-IIIBa-L) replication in fresh and cultured human peripheral blood monocytes/macrophages by azidothymidine and related 2',3'-dideoxynucleosides.

C F Perno;R Yarchoan;D A Cooney;N R Hartman.
Journal of Experimental Medicine (1988)

335 Citations

European guidelines on the clinical management of HIV-1 tropism testing

L.P.R. Vandekerckhove;Annemarie Wensing;Rolf Kaiser;F. Brun-Vézinet.
Lancet Infectious Diseases (2011)

312 Citations

Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir.

Stefano Aquaro;Raffaele Caliò;Jan Balzarini;Maria Concetta Bellocchi.
Antiviral Research (2002)

251 Citations

2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.

Jan Balzarini;María Jesús Pérez-Pérez;Ana San-Félix;Dominique Schols.
Proceedings of the National Academy of Sciences of the United States of America (1992)

246 Citations

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