2023 - Research.com Chemistry in Belgium Leader Award
2023 - Research.com Microbiology in Belgium Leader Award
2022 - Research.com Microbiology in Belgium Leader Award
2003 - Member of the European Academy of Sciences
Jan Balzarini focuses on Stereochemistry, Virology, Virus, Biochemistry and In vitro. His biological study spans a wide range of topics, including Biological activity, Structure–activity relationship, Chemical synthesis and Cytotoxicity. His research links Cell culture with Virology.
His work carried out in the field of Virus brings together such families of science as Reverse transcriptase, Microbiology and Mechanism of action. His research investigates the link between Biochemistry and topics such as Molecular biology that cross with problems in Kinase. The various areas that he examines in his In vitro study include RNA, DNA, In vivo and Pharmacology.
His primary areas of study are Stereochemistry, Biochemistry, Virology, Nucleoside and Virus. His Stereochemistry study combines topics in areas such as Biological activity, In vitro, Structure–activity relationship and Chemical synthesis. His Structure–activity relationship research integrates issues from Moiety and Cytotoxicity.
His Biochemistry study frequently draws connections between adjacent fields such as Molecular biology. His Virology research is multidisciplinary, incorporating elements of Cell culture, Reverse transcriptase and Mutant. His Nucleoside research includes themes of Prodrug and Thymidine kinase.
His main research concerns Stereochemistry, Biochemistry, Nucleoside, Prodrug and Structure–activity relationship. His work deals with themes such as Cell culture, In vitro, Reverse transcriptase and DNA, which intersect with Stereochemistry. Biochemistry is often connected to Molecular biology in his work.
His Nucleoside research includes elements of Nucleobase, Nucleotide, Deoxyuridine and Enzyme. His Prodrug study integrates concerns from other disciplines, such as Protide, Nucleoside triphosphate, Phosphoramidate, Biological activity and Dipeptidyl peptidase. His Structure–activity relationship research is multidisciplinary, relying on both Apoptosis, Tubulin, Cell growth and Cytotoxicity.
Jan Balzarini mainly investigates Stereochemistry, Biochemistry, Structure–activity relationship, In vitro and DNA. Jan Balzarini combines subjects such as Molecule, Prodrug and Reverse transcriptase with his study of Stereochemistry. The study incorporates disciplines such as Molecular biology and Virus in addition to Biochemistry.
His Virus study is associated with Virology. His research integrates issues of Cell culture, Viral replication, Cell growth, Apoptosis and Cytotoxicity in his study of Structure–activity relationship. His studies deal with areas such as Nucleobase, Thymidine and Uridine as well as Nucleoside.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds
Rudi Pauwels;Jan Balzarini;Masanori Baba;Robert Snoeck.
Journal of Virological Methods (1988)
A novel selective broad-spectrum anti-DNA virus agent.
Erik De Clercq;Antonin Holý;Ivan Rosenberg;Takashi Sakuma.
Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines.
Erik De Clercq;Takashi Sakuma;Masanori Baba;Rudi Pauwels.
Antiviral Research (1987)
Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro.
M Baba;R Pauwels;J Balzarini;J Arnout.
Proceedings of the National Academy of Sciences of the United States of America (1988)
Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs
J Wijnholds;C A Mol;L van Deemter;M de Haas.
Proceedings of the National Academy of Sciences of the United States of America (2000)
A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.
Tadashi Miyasaka;Hiromichi Tanaka;Masanori Baba;Hiroyuki Hayakawa.
Journal of Medicinal Chemistry (1989)
Early restaging positron emission tomography with 18F-fluorodeoxyglucose predicts outcome in patients with aggressive non-Hodgkin’s lymphoma
K. Spaepen;S. Stroobants;P. Dupont;P. Vandenberghe.
Annals of Oncology (2002)
Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.
J Balzarini;P Herdewijn;E De Clercq.
Journal of Biological Chemistry (1989)
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
P Herdewijn;J Balzarini;E De Clercq;R Pauwels.
Journal of Medicinal Chemistry (1987)
Characterization of the Transport of Nucleoside Analog Drugs by the Human Multidrug Resistance Proteins MRP4 and MRP5
Glen Reid;Peter Wielinga;Noam Zelcer;Marcel de Haas.
Molecular Pharmacology (2003)
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