D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 55 Citations 11,309 269 World Ranking 6661 National Ranking 85
Microbiology D-index 68 Citations 15,866 293 World Ranking 689 National Ranking 14

Overview

What is he best known for?

The fields of study he is best known for:

  • Virus
  • Enzyme
  • Organic chemistry

His scientific interests lie mostly in Virology, Virus, Stereochemistry, Chemical synthesis and Structure–activity relationship. All of his Virology and Human cytomegalovirus, Cidofovir, Viral replication, Thymidine kinase and Ganciclovir investigations are sub-components of the entire Virology study. His work carried out in the field of Virus brings together such families of science as Vaccinia and Microbiology.

His research in Stereochemistry intersects with topics in Biological activity, DNA, Purine and Stereoisomerism. His Chemical synthesis study combines topics from a wide range of disciplines, such as Phosphonate, Bicyclic molecule and Pyrimidine. His Structure–activity relationship research focuses on subjects like Deoxyribonucleoside, which are linked to Deoxyuridine and Substituent.

His most cited work include:

  • Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds (1426 citations)
  • Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus. (445 citations)
  • Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine. (290 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Virology, Stereochemistry, Virus, Nucleoside and Cidofovir. His Virology study is mostly concerned with Herpes simplex virus, Human cytomegalovirus, Thymidine kinase, Viral replication and Foscarnet. His Stereochemistry research incorporates themes from Biological activity, Structure–activity relationship and Chemical synthesis.

Robert Snoeck has included themes like Vaccinia, In vitro and Cell culture in his Virus study. His Nucleoside research is multidisciplinary, incorporating elements of Prodrug and Cytotoxicity. Robert Snoeck regularly links together related areas like Cytosine in his Cidofovir studies.

He most often published in these fields:

  • Virology (39.68%)
  • Stereochemistry (35.69%)
  • Virus (26.70%)

What were the highlights of his more recent work (between 2014-2021)?

  • Stereochemistry (35.69%)
  • Virology (39.68%)
  • Virus (26.70%)

In recent papers he was focusing on the following fields of study:

His main research concerns Stereochemistry, Virology, Virus, DNA and RNA. He interconnects Cell culture, HeLa, Uracil, Nucleotide and Prodrug in the investigation of issues within Stereochemistry. His studies in Prodrug integrate themes in fields like Protide, Guanine, Pyrimidine, Phosphoramidate and Nucleoside.

Virology is represented through his Herpes simplex virus, Human cytomegalovirus, Varicella zoster virus, Viral replication and Cidofovir research. Robert Snoeck studies Virus, focusing on Thymidine kinase in particular. His DNA study integrates concerns from other disciplines, such as Phosphonate, IC50, Structure–activity relationship and Nitrone.

Between 2014 and 2021, his most popular works were:

  • Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma (116 citations)
  • Mouse Cytomegalovirus Infection in BALB/c Mice Resembles Virus-Associated Secondary Hemophagocytic Lymphohistiocytosis and Shows a Pathogenesis Distinct from Primary Hemophagocytic Lymphohistiocytosis (33 citations)
  • Insights into the mechanism of action of cidofovir and other acyclic nucleoside phosphonates against polyoma- and papillomaviruses and non-viral induced neoplasia. (31 citations)

In his most recent research, the most cited papers focused on:

  • Virus
  • Enzyme
  • DNA

His primary areas of study are Stereochemistry, Virology, DNA, Virus and RNA. His Stereochemistry research is multidisciplinary, incorporating perspectives in Phosphonate, IC50, Prodrug, HeLa and Structure–activity relationship. Virology is closely attributed to Macrophage activation syndrome in his research.

His studies deal with areas such as Thymidine kinase and Potency as well as DNA. His research integrates issues of Combinatorial chemistry, Amino acid and Gene in his study of Virus. His Herpes simplex virus study which covers Human cytomegalovirus that intersects with DNA polymerase, Varicella zoster virus and Pyrimidine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

Rudi Pauwels;Jan Balzarini;Masanori Baba;Robert Snoeck.
Journal of Virological Methods (1988)

2327 Citations

Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus.

M Baba;R Snoeck;R Pauwels;E de Clercq.
Antimicrobial Agents and Chemotherapy (1988)

695 Citations

Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine.

J Balzarini;A Holy;J Jindrich;L Naesens.
Antimicrobial Agents and Chemotherapy (1993)

440 Citations

Synthesis and antiviral activity of new pyrazole and thiazole derivatives

Osama I. El-Sabbagh;Mohamed M. Baraka;Samy M. Ibrahim;Christophe Pannecouque.
European Journal of Medicinal Chemistry (2009)

336 Citations

Treatment of Severe Laryngeal Papillomatosis With Intralesional Injections of Cidofovir ((S)-1-(3-Hydroxy-2-Phosphonylmethoxypropyl) Cytosine)

Robert Snoeck;Willy Wellens;Christian Desloovere;Mark Van Ranst.
Journal of Medical Virology (1998)

330 Citations

HPMPC (cidofovir), PMEA (adefovir) and related acyclic nucleoside phosphonate analogues: a review of their pharmacology and clinical potential in the treatment of viral infections

L Naesens;R Snoeck;G Andrei;J Balzarini.
Antiviral Chemistry & Chemotherapy (1997)

303 Citations

(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication.

R Snoeck;T Sakuma;E De Clercq;I Rosenberg.
Antimicrobial Agents and Chemotherapy (1988)

297 Citations

Activities of various compounds against murine and primate polyomaviruses.

G Andrei;R Snoeck;M Vandeputte;E De Clercq.
Antimicrobial Agents and Chemotherapy (1997)

273 Citations

Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base.

Christopher McGuigan;Christopher J. Yarnold;Garry Jones;Sonsoles Velázquez.
Journal of Medicinal Chemistry (1999)

240 Citations

Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base

Antonín Holý;Jaroslav Günter;Hana Dvořáková;Milena Masojídková.
Journal of Medicinal Chemistry (1999)

235 Citations

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