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Piet Herdewijn

Piet Herdewijn

KU Leuven
Belgium

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Chemistry
Belgium
2025
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Biology and Biochemistry
Belgium
2023

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Chemistry 89 2144 1923 25 24 1043 32026
Biology and Biochemistry 89 2530 2319 39 38 1030 32078

Piet Herdewijn publications per year

The chart shows the history of publications by Piet Herdewijn between 1981 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Piet Herdewijn published across 45 years, from 1981 to 2025, averaging 24.7 papers a year. Output peaked at 50 publications in 2007. 15 of the 1,112 publications appeared in the last two years.

No. of publications
10 20 30 40 50
Bar chart. Horizontal axis: year, 1981 to 2025. Vertical axis: number of publications, 0 to 50. Peak 50 publications in 2007. 1981: 1 publication 1982: 3 publications 1983: 2 publications 1984: 5 publications 1985: 9 publications 1986: 8 publications 1987: 17 publications 1988: 17 publications 1989: 27 publications 1990: 20 publications 1991: 40 publications 1992: 16 publications 1993: 28 publications 1994: 24 publications 1995: 46 publications 1996: 41 publications 1997: 43 publications 1998: 30 publications 1999: 49 publications 2000: 31 publications 2001: 27 publications 2002: 31 publications 2003: 34 publications 2004: 34 publications 2005: 29 publications 2006: 34 publications 2007: 50 publications 2008: 35 publications 2009: 26 publications 2010: 47 publications 2011: 27 publications 2012: 28 publications 2013: 22 publications 2014: 23 publications 2015: 27 publications 2016: 20 publications 2017: 17 publications 2018: 30 publications 2019: 27 publications 2020: 20 publications 2021: 19 publications 2022: 11 publications 2023: 22 publications 2024: 8 publications 2025: 7 publications
1981 2025

1,112 publications in total across all disciplines

View publications per year as a table
Piet Herdewijn: publications per year, 1981 to 2025
Year Publications
1981 1
1982 3
1983 2
1984 5
1985 9
1986 8
1987 17
1988 17
1989 27
1990 20
1991 40
1992 16
1993 28
1994 24
1995 46
1996 41
1997 43
1998 30
1999 49
2000 31
2001 27
2002 31
2003 34
2004 34
2005 29
2006 34
2007 50
2008 35
2009 26
2010 47
2011 27
2012 28
2013 22
2014 23
2015 27
2016 20
2017 17
2018 30
2019 27
2020 20
2021 19
2022 11
2023 22
2024 8
2025 7
Total 1,112
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Piet Herdewijn publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Piet Herdewijn sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 63 bars. Horizontal axis: publications, 61–80 to 1,295+. Vertical axis: number of scientists, 0 to 1,350. Most scientists, 1,350, have 161–180 publications. The last bar groups every scientist with 1,295 publications or more. The highlighted bar, 1,041–1,060 publications, is where this scientist sits. 61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61–80 publications 1,295+

This scientist: 1,043 publications — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

View publications distribution as a table
Number of Chemistry scientists by publication count, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
Publications Scientists This scientist
61–80 66
81–100 302
101–120 623
121–140 918
141–160 1,218
161–180 1,350
181–200 1,344
201–220 1,281
221–240 1,216
241–260 1,100
261–280 979
281–300 939
301–320 764
321–340 643
341–360 628
361–380 522
381–400 459
401–420 397
421–440 327
441–460 270
461–480 265
481–500 252
501–520 201
521–540 185
541–560 148
561–580 148
581–600 132
601–620 114
621–640 104
641–660 91
661–680 92
681–700 73
701–720 57
721–740 54
741–760 67
761–780 45
781–800 46
801–820 39
821–840 32
841–860 36
861–880 29
881–900 26
901–920 24
921–940 14
941–960 23
961–980 28
981–1,000 15
1,001–1,020 29
1,021–1,040 12
1,041–1,060 19 1,043
1,061–1,080 12
1,081–1,100 6
1,101–1,120 8
1,121–1,140 12
1,141–1,160 5
1,161–1,180 6
1,181–1,200 14
1,201–1,220 7
1,221–1,240 2
1,241–1,260 6
1,261–1,280 4
1,281–1,294 6
1,295+ 100
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Piet Herdewijn D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Piet Herdewijn sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 61 bars. Horizontal axis: D-Index, 40–41 to 159+. Vertical axis: number of scientists, 0 to 1,051. Most scientists, 1,051, have 56–57 D-Index. The last bar groups every scientist with 159 D-Index or more. The highlighted bar, 88–89 D-Index, is where this scientist sits. 40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40–41 D-Index 159+

This scientist: 89 D-Index — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

View D-Index distribution as a table
Number of Chemistry scientists by D-index, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
D-Index Scientists This scientist
40–41 289
42–43 612
44–45 808
46–47 776
48–49 835
50–51 861
52–53 872
54–55 933
56–57 1,051
58–59 930
60–61 882
62–63 834
64–65 731
66–67 775
68–69 683
70–71 646
72–73 561
74–75 501
76–77 437
78–79 388
80–81 354
82–83 292
84–85 275
86–87 254
88–89 235 89
90–91 185
92–93 192
94–95 155
96–97 163
98–99 125
100–101 105
102–103 105
104–105 112
106–107 88
108–109 68
110–111 69
112–113 65
114–115 79
116–117 61
118–119 44
120–121 37
122–123 40
124–125 33
126–127 26
128–129 34
130–131 35
132–133 25
134–135 27
136–137 17
138–139 16
140–141 20
142–143 20
144–145 15
146–147 9
148–149 9
150–151 16
152–153 11
154–155 9
156–157 3
158 3
159+ 98
Download as CSV

Research.com Recognitions

  • 2025 - Research.com Chemistry in Belgium Leader Award
  • 2023 - Research.com Biology and Biochemistry in Belgium Leader Award
  • 2022 - Research.com Chemistry in Belgium Leader Award

Overview

Piet Herdewijn is affiliated with KU Leuven in Belgium and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with significant work also intersecting medicine. Their research portfolio includes over a hundred publications, reflecting a sustained focus on molecular biology and related subfields such as infectious diseases, organic chemistry, epidemiology, and virology.

Their main topics of study encompass:

  • DNA and Nucleic Acid Chemistry
  • HIV/AIDS drug development and treatment
  • Advanced biosensing and bioanalysis techniques
  • RNA and protein synthesis mechanisms
  • HIV Research and Treatment
  • Bacteriophages and microbial interactions
  • Biochemical and Molecular Research

Frequently publishing in scientific venues, Herdewijn has multiple articles in the European Journal of Medicinal Chemistry and the journal Nucleic Acids Research. Other common publication venues include UNC Libraries, ACS Medicinal Chemistry Letters, and the Journal of Medicinal Chemistry.

Several coauthors have frequently collaborated with Herdewijn, including Elisabetta Groaz, Steven De Jonghe, Mikhail Abramov, Eveline Lescrinier, and Dominique Schols.

Selected recent papers illustrate the range of Herdewijn's research outputs:

  • Noncanonical DNA polymerization by aminoadenine-based siphoviruses, 2021, Science
  • A two-residue nascent-strand steric gate controls synthesis of 2'-O-methyl- and 2'-O-(2-methoxyethyl)-RNA, 2022, Nature Chemistry
  • Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc-siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5'-exonuclease, 2020, Nucleic Acids Research
  • Functional Comparison of Laboratory-Evolved XNA Polymerases for Synthetic Biology, 2021, ACS Synthetic Biology
  • An Overview of Marketed Nucleoside and Nucleotide Analogs, 2022, Current Protocols

Best Publications

  • Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

    Rudi Pauwels;Jan Balzarini;Masanori Baba;Robert Snoeck

  • Synthetic genetic polymers capable of heredity and evolution

    Vitor B. Pinheiro;Alexander I. Taylor;Christopher Cozens;Mikhail Abramov

  • Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro

    Masanori Baba;Rudi Pauwels;Piet Herdewijn;Erik De Clercq

  • Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.

    J Balzarini;P Herdewijn;E De Clercq

  • 3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.

    P Herdewijn;J Balzarini;E De Clercq;R Pauwels

  • A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

    Jesper B. Bramsen;Maria B. Laursen;Anne F. Nielsen;Thomas B. Hansen

  • Modifications in Lignin and Accumulation of Phenolic Glucosides in Poplar Xylem upon Down-regulation of Caffeoyl-Coenzyme A O-Methyltransferase, an Enzyme Involved in Lignin Biosynthesis

    Hugo Meyermans;Kris Morreel;Catherine Lapierre;Brigitte Pollet

  • The anti-HTLV-III (anti-HIV) and cytotoxic activity of 2',3'-didehydro-2',3'-dideoxyribonucleosides: a comparison with their parental 2',3'-dideoxyribonucleosides.

    J Balzarini;G J Kang;M Dalal;P Herdewijn

  • Catalysts from synthetic genetic polymers

    Alexander I. Taylor;Vitor B. Pinheiro;Vitor B. Pinheiro;Matthew J. Smola;Alexey S. Morgunov

  • Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound.

    J. Balzarini;Zhang Hao;P. Herdewijn;D. G. Johns

  • Marked in vivo antiretrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine, a selective anti-human immunodeficiency virus agent.

    J Balzarini;L Naesens;P Herdewijn;I Rosenberg

  • Sensitive and rapid assay on MT-4 cells for detection of antiviral compounds against the AIDS virus.

    Rudi Pauwels;Erik De Clercq;Jan Desmyter;Jan Balzarini

  • The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3′-azido-2′,3′-dideoxythymidine and 2′,3′-dideoxycytidine are highly dependent on the cell species

    Jan Balzarini;Rudi Pauwels;Masanori Baba;Piet Herdewijn

  • Anti-retrovirus activity of 3′-fluoro- and 3′-azido-substituted pyrimidine 2′,3′-dideoxynucleoside analogues

    Jan Balzarini;Masanori Baba;Rudi Pauwels;Piet Herdewijn

  • Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral

    Leen Delang;Nidya Segura Guerrero;Ali Tas;Gilles Quérat

  • Potent and selective anti-HTLV-III/LAV activity of 2',3'-dideoxycytidinene, the 2',3'-unsaturated derivative of 2',3'-dideoxycytidine.

    Jan Balzarini;Rudi Pauwels;Piet Herdewijn;Erik De Clercq

  • Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects

    Elena Bekerman;Gregory Neveu;Ana Shulla;Jennifer Brannan

  • α-l-ribo-Configured Locked Nucleic Acid (α-L-LNA): Synthesis and Properties

    Mads D. Sørensen;Lisbet Kvaernø;Torsten Bryld;Anders E. Hakansson

  • Ribavirin antagonizes inhibitory effects of pyrimidine 2',3'-dideoxynucleosides but enhances inhibitory effects of purine 2',3'-dideoxynucleosides on replication of human immunodeficiency virus in vitro.

    M Baba;R Pauwels;J Balzarini;P Herdewijn

  • Chemical Evolution of a Bacterium’s Genome

    Philippe Marlière;Julien Patrouix;Volker Döring;Piet Herdewijn

  • Strategies in the Design of Antiviral Drugs

    Erik De Clercq;Piet Herdewijn

Frequent Co-Authors

Erik De Clercq
Erik De Clercq Rega Institute for Medical Research
Jan Balzarini
Jan Balzarini KU Leuven
Christophe Pannecouque
Christophe Pannecouque Rega Institute for Medical Research
Johan Neyts
Johan Neyts Rega Institute for Medical Research
Robert Snoeck
Robert Snoeck KU Leuven
Denis De Keukeleire
Denis De Keukeleire Ghent University
Rudi Pauwels
Rudi Pauwels Tibotec
Jos Hoogmartens
Jos Hoogmartens KU Leuven
Erik De Clercq
Erik De Clercq KU Leuven
Jozef Anné
Jozef Anné KU Leuven

External Links

Personal website of Piet Herdewijn

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Best Scientists Citing Piet Herdewijn

Erik De Clercq

Erik De Clercq

Rega Institute for Medical Research

Publications: 332

Jan Balzarini

Jan Balzarini

KU Leuven

Publications: 269

Christophe Pannecouque

Christophe Pannecouque

Rega Institute for Medical Research

Publications: 201

Johan Neyts

Johan Neyts

Rega Institute for Medical Research

Publications: 122

Jesper Wengel

Jesper Wengel

Aalborg University

Publications: 102

Paolo La Colla

Paolo La Colla

University of Cagliari

Publications: 92

Dominique Schols

Dominique Schols

KU Leuven

Publications: 90

Myriam Witvrouw

Myriam Witvrouw

KU Leuven

Publications: 86

Masanori Baba

Masanori Baba

Kagoshima University

Publications: 81

Eric E. Swayze

Eric E. Swayze

Ionis Pharmaceuticals (United States)

Publications: 68

John Ralph

John Ralph

Great Lakes Bioenergy Research Center

Publications: 66

Graciela Andrei

Graciela Andrei

KU Leuven

Publications: 58

Robert Snoeck

Robert Snoeck

KU Leuven

Publications: 58

Punit P. Seth

Punit P. Seth

Ionis Pharmaceuticals (United States)

Publications: 56

Erik De Clercq

Erik De Clercq

KU Leuven

Publications: 55

Erik B. Pedersen

Erik B. Pedersen

University of Southern Denmark

Publications: 55

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