What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in RNA, Biochemistry, Nucleic acid, Oligonucleotide and Nuclease.
His biological study deals with issues like Potency, which deal with fields such as Toxicity and Nucleotide.
His study in the field of Gene expression, Ribosomal RNA and Internal ribosome entry site also crosses realms of Therapeutic gene modulation.
Eric E. Swayze combines subjects such as Molecular biology, Antisense RNA and RNase H with his study of Oligonucleotide.
He has researched Nuclease in several fields, including Bicyclic molecule and Stereochemistry.
His research integrates issues of Ring and Hepatitis C virus in his study of Stereochemistry.
His most cited work include:
- RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform (906 citations)
- 6-modified bicyclic nucleic acid analogs (409 citations)
- Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA. (385 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Stereochemistry, RNA, Biochemistry, Nucleic acid and Oligonucleotide.
His study looks at the relationship between Stereochemistry and fields such as Combinatorial chemistry, as well as how they intersect with chemical problems.
Eric E. Swayze interconnects Double stranded and Cell biology in the investigation of issues within RNA.
His work on Nucleotide, Potency and Gene expression as part of his general Biochemistry study is frequently connected to Conjugate, thereby bridging the divide between different branches of science.
His Nucleic acid research incorporates elements of Nucleoside analogue, DNA and Therapeutic index.
His study on Oligonucleotide also encompasses disciplines like
- Molecular biology which is related to area like Gene silencing,
- Messenger RNA which connect with Pharmacology.
He most often published in these fields:
- Stereochemistry (36.28%)
- RNA (27.44%)
- Biochemistry (25.61%)
What were the highlights of his more recent work (between 2018-2021)?
- Oligonucleotide (22.87%)
- Pharmacology (5.79%)
- In vivo (7.62%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Oligonucleotide, Pharmacology, In vivo, Messenger RNA and Cell biology.
His Oligonucleotide research includes themes of Cleavage, Nucleobase, Biophysics, Sequence and Albumin.
His Cell biology research includes elements of RNA, Gene and Gene isoform.
His biological study spans a wide range of topics, including Phosphate, Medicinal chemistry and Function.
His research investigates the connection between Cancer research and topics such as Transthyretin that intersect with problems in Biochemistry.
His work on Stereochemistry is being expanded to include thematically relevant topics such as Nuclease.
Between 2018 and 2021, his most popular works were:
- Antisense oligonucleotides extend survival of prion-infected mice (42 citations)
- Characterization of the interactions of chemically-modified therapeutic nucleic acids with plasma proteins using a fluorescence polarization assay. (39 citations)
- Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle (36 citations)
In his most recent research, the most cited papers focused on:
- Gene
- DNA
- Organic chemistry
The scientist’s investigation covers issues in Plasma protein binding, Oligonucleotide, Pharmacology, Albumin and Blood proteins.
Many of his studies involve connections with topics such as RNA and Plasma protein binding.
His Oligonucleotide study combines topics in areas such as Biophysics, Cleavage and Protein–protein interaction.
His research in Biophysics intersects with topics in Nucleic acid, Glycoprotein and Nuclease.
His Pharmacology study integrates concerns from other disciplines, such as Potency, Spinal muscular atrophy, Cell type and Mechanism of action.
His Blood proteins course of study focuses on Cholesterol and Skeletal muscle, Cardiac muscle, Molecular biology and Myocyte.
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